KEGG   Escherichia sp. E4742: FEM44_09800
Entry
FEM44_09800       CDS       T06276                                 
Symbol
ilvC
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
esz  Escherichia sp. E4742
Pathway
esz00290  Valine, leucine and isoleucine biosynthesis
esz00770  Pantothenate and CoA biosynthesis
esz01100  Metabolic pathways
esz01110  Biosynthesis of secondary metabolites
esz01210  2-Oxocarboxylic acid metabolism
esz01230  Biosynthesis of amino acids
Module
esz_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
esz_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:esz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    FEM44_09800 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    FEM44_09800 (ilvC)
Enzymes [BR:esz01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     FEM44_09800 (ilvC)
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C NAD_binding_7 ApbA AdoHcyase_NAD Sacchrp_dh_NADP
Other DBs
NCBI-ProteinID: QCT87492
LinkDB
Position
complement(2017237..2018712)
AA seq 491 aa
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSG
LDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQP
LMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPE
NDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKL
VEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLF
QKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVL
MIAMVKAGVEMAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYG
NYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGY
MTDMKRIAVAG
NT seq 1476 nt   +upstreamnt  +downstreamnt
atggctaactacttcaatacactgaatctgcgccagcagctggcacagctgggcaaatgt
cgctttatgggccgcgacgaattcgctgacggcgcgagctaccttcagggtaaaaaagtg
gtcatcgtcggctgtggtgcacagggtctgaaccagggtctgaatatgcgtgattctggt
ctcgatatctcctacgctctgcgtaaagaagcgattgccgagaagcgcgcatcctggcgt
aaagcgaccgaaaacggttttaaagttggtacttacgaagaactgatcccgcaggcggat
ctggtggttaacttgacgccggacaagcagcactctgatgtagtgcgcaccgtacagcca
ctgatgaaagacggagcggcgctgggttactcgcacggtttcaacatcgtcgaagtgggc
gagcagatccgtaaagacatcaccgtagtaatggttgcgccgaaatgccctggcaccgaa
gtacgtgaagagtacaaacgaggattcggcgtaccgacgctgattgccgttcacccggaa
aacgatccgaaaggcgaaggcatggcgatcgctaaagcctgggcggcggcaaccggtggt
catcgtgcgggcgtgctggaatcctccttcgttgcggaagtgaaatctgacctgatgggc
gagcagactattctgtgcggtatgctgcaggccggctctctgctgtgcttcgacaagctg
gtggaagaaggcaccgacccggcatacgcagaaaaactgattcagttcggttgggaaaca
atcaccgaagcactgaaacagggcggcatcaccctgatgatggacaggctctctaacccg
gcaaaactgcgagcttacgcgctgtcagaacaactgaaagagatcatggcaccgctgttc
cagaaacatatggacgacatcatctccggcgaattctcctccggcatgatggcggactgg
gccaacgacgataagaaactgctgacctggcgtgaagaaaccggcaaaaccgcgttcgaa
accgcgccgcagtatgaaggtaaaatcggcgagcaggagtacttcgataaaggcgtactg
atgatcgcaatggtaaaagcgggcgttgaaatggcgttcgaaaccatggttgattccggc
atcattgaagaatctgcttattatgaatcactgcacgaactgccgctgattgccaacacc
atcgcccgtaagcgcctgtacgaaatgaacgtggttatctctgataccgccgagtacggt
aactatctgttctcttacgcttgtgtgccgttgctgaaaccgtttatggcagagctgcaa
ccgggcgacctgggtaaagctattccggaaggtgcggtagataacgcgcagttgcgtgat
gtgaatgaagcgattcgcagccatgcgattgagcaggtaggtaagaaactgcgcggctat
atgacggatatgaaacgtattgctgttgcgggttaa

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