Escherichia sp. E4742: FEM44_14845
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Entry
FEM44_14845 CDS
T06276
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
esz
Escherichia sp. E4742
Pathway
esz00290
Valine, leucine and isoleucine biosynthesis
esz00660
C5-Branched dibasic acid metabolism
esz01100
Metabolic pathways
esz01110
Biosynthesis of secondary metabolites
esz01210
2-Oxocarboxylic acid metabolism
esz01230
Biosynthesis of amino acids
Module
esz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
esz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
FEM44_14845 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
FEM44_14845 (leuC)
Enzymes [BR:
esz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
FEM44_14845 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
FEM44_14845 (leuC)
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Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
QCT88368
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Position
complement(3047111..3048511)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQAGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDEITF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEIAPQVTWGTNPGQVISV
NENIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattgttcgacgctcacgtagtctacgaagccgaaaac
gaaaccccgctgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggcctgcgcgcccacggtcgcccggtgcgtcaggcggggaaaaccttcgccacc
atggatcacaacgtctcaactcagactaaagacattaatgcctgcggtgaaatggcgcgg
atccagatgcaggagcttattaaaaactgcaaagaatttggcgtcgagctgtatgacctg
aatcacccgtatcaggggatcgtccacgtgatggggccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggtgcgctg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggtcgtgcgaagactatgaaaattgaagtccagggcaaagccgcaccgggcattaccgcg
aaagatatcgtgctggcgatcattggtaaaaccggcagcgcaggcggcaccgggcatgta
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcgaaagccggtctggttgcaccggacgaaatcaccttt
aactatgttaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgatgccgtcgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagagattgccccgcaggtgacctggggaactaacccaggacaggtgatctccgtt
aacgagaatatccctgatcccgcttcatttgccgatccggttgaacgcgcgtcggcagaa
aaagcactggcctatatgggactgaaaccgggtattccgctgactgaagtggctatcgac
aaagtgtttattggttcctgtaccaactcgcgcattgaagatttacgcgcggcagcggaa
atcgccaaagggcgaaaagtcgcgccaggcgtacaggcactggtggttcccggctctggc
ccggtaaaagctcaggcggaagcagaaggtctggacaaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccc
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggt
cgcacgcatctggtcagcccggcaatggctgccgccgctgctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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