Escherichia sp. E4742: FEM44_14915
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Entry
FEM44_14915 CDS
T06276
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
esz
Escherichia sp. E4742
Pathway
esz00300
Lysine biosynthesis
esz00550
Peptidoglycan biosynthesis
esz01100
Metabolic pathways
esz01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
esz00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FEM44_14915 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FEM44_14915 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FEM44_14915 (murF)
Enzymes [BR:
esz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FEM44_14915 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
QCT88380
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Position
3062291..3063649
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELKGEDVTLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
ANAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKSALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaactcttagccaacttaccgatattctcaacggtgaactaaaaggggaa
gatgtcaccctggatgccgtaacgactgacactcggaaactgacgccaggctgtctgttt
gtcgccctgaaaggcgaacgtttcgatgcccacgattttgccgaccaggcgaaagctggc
ggcgcaggtgcattactggtcagccgtccgctggatatcgacctgccgcagttaatcgtt
aaagacacgcgtctggcattcggtgaactggctgcatgggtacgccagcaagttccggcg
cgtgtggttgctctgaccggttcctccggtaaaacctccgttaaagagatgactgcggcg
attttaagccagtgcggtaatacgctttataccgcgggcaatctcaacaacgacatcggc
gtgccaatgacgctgctgcgcttaacgccggaatacgattacgcagttatcgaacttggc
gcgaaccatcagggcgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcggcggcgcatctggaaggtttcggttctttggctggcgtggcaaaa
gcgaaaggcgaaatctttaccggcttgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
gccaatgctgccaacagcgatttcaccgccaccaatatccatgtgacttcgcacggtacg
gaatttacgctacaaaccccaacaggtagtgtcgatgttctgctaccgttgcccgggcgt
cacaatattgcgaatgcgctggcagccgccgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagccgttcccgggcgtctgttccccatt
caactggcggaaaaccagttgttgctcgacgactcctacaacgccaatgtcggttcaatg
accgcagcagtccaggtactggctgaaatgcctggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcgaag
gcagctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacattttgctgataaatccgcattaattgcgcgtcttaaatcactg
attgcagagcaacaggtgattacgattttagttaagggttcacgtagtgccgccatggaa
gaggtggtacgcgctttacaggagaatgggacatgctag
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