Echinops telfairi (small Madagascar hedgehog): 101638317
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Entry
101638317 CDS
T08707
Symbol
BACE1
Name
(RefSeq) beta-secretase 1 isoform X1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101638317 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
etf01002
]
101638317 (BACE1)
Enzymes [BR:
etf01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
101638317 (BACE1)
Peptidases and inhibitors [BR:
etf01002
]
Aspartic peptidases
Family A1: pepsin family
101638317 (BACE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
101638317
NCBI-ProteinID:
XP_004712848
LinkDB
All DBs
Position
Unknown
AA seq
498 aa
AA seq
DB search
MARALPWLLLWVGAGVLPAQCTPHGIRLPLRSGLGGTPLGLRLPRDTDEEPDEPSPRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDNSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVQVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRQQHDDFADDISLLK
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atggctcgggccctgccctggctcctgctgtgggtgggcgcgggagtgctgcccgcccag
tgcaccccacatggcattcggctgcctctgcggagcgggttaggggggacccccctgggg
ctccggctgcctcgggacaccgacgaggagccggacgagcccagcccgaggggcagcttt
gtggagatggtggacaacctgaggggcaagtcgggccagggctactacgtggagatgact
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagcagtaactttgcg
gtgggggctgccccccaccctttcctgcatcgctactaccagaggcagctgtccagcacg
taccgggacctccgcaagggcgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatcccccacggccccaacgtcaccgtgcgtgccaacatt
gctgccatcacagaatcagacaagttcttcatcaatggctccaactgggagggcatcctg
gggctggcctatgcggagattgccaggcctgacaactcactggagcccttctttgactcc
ctggtaaagcagacgcacgtgcccaacctcttctccctgcagctctgtggggccggcttc
cccctcaaccagtccgaggtgctggcctccgtgggagggagcatgatcatcggcggtatc
gaccactcgctgtacacaggcagtctctggtacactcccatccggcgagaatggtattac
gaagtgatcattgtgcaggtggaaatcaacggacaagatctgaaaatggactgcaaggag
tacaactacgacaagagcatcgtggacagcggcaccaccaacctccgtctgcccaagaaa
gtgtttgaggctgcagtcaaatccatcaaggcggcctcctcgacagagaagttcccagac
ggtttctggctaggggagcagctggtgtgctggcaagctggcaccaccccgtggaacatc
ttcccagtcatctccctctacctaatgggcgaggtcaccaaccagtccttccgcatcacc
atcctcccccagcaatacctgcggcccgtggaagatgtggccacatcccaggatgactgt
tacaagttcgccatctcccagtcctccacgggcactgtcatgggagctgtcatcatggag
ggcttctatgttgtcttcgaccgggcccgaaagagaattggctttgctgtcagcgcttgc
cacgtgcacgatgagttccggacggcggcggtggaaggcccctttgtcacgccggacatg
gaagactgtggctacaacatcccgcagacagacgagtcgaccctcatgaccatcgcctac
gtcatggctgccatctgcgccctcttcatgctgccactctgcctcatggtgtgccagtgg
cgctgcctgcgccagcaacacgacgactttgcggacgacatctccctgctcaagtga
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