Echinops telfairi (small Madagascar hedgehog): 101643319
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Entry
101643319 CDS
T08707
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01521
EGFR tyrosine kinase inhibitor resistance
etf01522
Endocrine resistance
etf04010
MAPK signaling pathway
etf04014
Ras signaling pathway
etf04015
Rap1 signaling pathway
etf04066
HIF-1 signaling pathway
etf04068
FoxO signaling pathway
etf04081
Hormone signaling
etf04114
Oocyte meiosis
etf04140
Autophagy - animal
etf04144
Endocytosis
etf04150
mTOR signaling pathway
etf04151
PI3K-Akt signaling pathway
etf04152
AMPK signaling pathway
etf04211
Longevity regulating pathway
etf04213
Longevity regulating pathway - multiple species
etf04510
Focal adhesion
etf04520
Adherens junction
etf04550
Signaling pathways regulating pluripotency of stem cells
etf04730
Long-term depression
etf04913
Ovarian steroidogenesis
etf04914
Progesterone-mediated oocyte maturation
etf05200
Pathways in cancer
etf05202
Transcriptional misregulation in cancer
etf05205
Proteoglycans in cancer
etf05214
Glioma
etf05215
Prostate cancer
etf05218
Melanoma
etf05224
Breast cancer
etf05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101643319 (IGF1R)
04014 Ras signaling pathway
101643319 (IGF1R)
04015 Rap1 signaling pathway
101643319 (IGF1R)
04066 HIF-1 signaling pathway
101643319 (IGF1R)
04068 FoxO signaling pathway
101643319 (IGF1R)
04151 PI3K-Akt signaling pathway
101643319 (IGF1R)
04152 AMPK signaling pathway
101643319 (IGF1R)
04150 mTOR signaling pathway
101643319 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
101643319 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101643319 (IGF1R)
04140 Autophagy - animal
101643319 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
101643319 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101643319 (IGF1R)
04520 Adherens junction
101643319 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
101643319 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101643319 (IGF1R)
04914 Progesterone-mediated oocyte maturation
101643319 (IGF1R)
09156 Nervous system
04730 Long-term depression
101643319 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
101643319 (IGF1R)
04213 Longevity regulating pathway - multiple species
101643319 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101643319 (IGF1R)
05202 Transcriptional misregulation in cancer
101643319 (IGF1R)
05205 Proteoglycans in cancer
101643319 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101643319 (IGF1R)
05214 Glioma
101643319 (IGF1R)
05218 Melanoma
101643319 (IGF1R)
05215 Prostate cancer
101643319 (IGF1R)
05224 Breast cancer
101643319 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101643319 (IGF1R)
01522 Endocrine resistance
101643319 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101643319 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
etf04090
]
101643319 (IGF1R)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101643319 (IGF1R)
Protein kinases [BR:
etf01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101643319 (IGF1R)
CD molecules [BR:
etf04090
]
Proteins
101643319 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101643319
NCBI-ProteinID:
XP_045152404
LinkDB
All DBs
Position
Unknown
AA seq
1359 aa
AA seq
DB search
MILVVFEILGADLSASCRPPQHICGPGIDIRNDYQQLRRLENCTVIEGFLHILLISKVED
YRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIG
LYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPQKECGDLCPGSMEEK
SLCEKTSINNEYNYRCWTTDHCQKMCPSVCGKRACSQAGECCHEECLGSCTAPDNATACV
ACRHYYFLGTCVTTCPPNTYKFEGWRCVDRDFCANILNAESTEFEGFVIHNGECMQECPS
GFIRNGTLSMFCVPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNN
IASELENFMGLIEIVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSFYVLDNQNLQ
QLWDWEHRNLTIKEGKMYFAFNPKLCVSEIYRMEEVTGTKGRQNKGDINTRNNGERASCE
SDVLHFTSTNTWKNHIIITWHRYRPPDYRDLISFTVYYKEAPYKNVTEYDGQDACGSNSW
NMVDVDLPTNKDVEPGILLHSLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNAS
VPSVPLDVHSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDGYLYQHNYCSKDKIP
IRKYADGTIDIEEVTENPKTEVCGGQKGPCCACPKTEAEKQTEKEEAEYRKVFENFLHNS
IFVPRPERKRRDVMQVANMSLSGRARNITGGDGYNLTDPDELETEFPFYESRVDNKERTV
ISNLRPFTLYRIDIHSCNHEAEQLGCSASNFVFARTKPADGADDIPGPVTWESRPENSIF
LKWPEPENPNGLILMYEIKYGSLVEDQRECVSRQDYEKYGGAKLNRLNPGNYTARIQATS
LSGNGSWTDPVFFYVPTKIRPYENFMHLIIALPVAVLMVAGGLVIMLYVCHRKRINSRLG
NGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPET
RVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLK
SYLRSLRPEMENNPVLAPPSLTKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFT
VKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWEIATL
AEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKD
EMEPGFEEVSFFYSEENKPPEPEDLDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENG
PGPGMLLLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4080 nt
NT seq
+upstream
nt +downstream
nt
atgatcttggtggtgttcgagatactgggggcagacctctcagcatcatgcagaccgccc
cagcacatctgcgggccgggcattgacatccgcaatgactaccagcagctgcggcgcctg
gagaactgcactgtgatcgagggcttcctgcacatcctgctcatctccaaggtggaggac
taccgcagctaccgcttccccaagctgaccgtcatcaccgagtacttgctgctcttccgt
gtggccggcctggagagccttggcgacctcttcccaaacctcacggtcatccgtggctgg
aagctcttctacaattatgccttggtcatttttgagatgactaacctcaaagatattggg
ctctataacctcaggaacattactcggggggccatcaggattgaaaaaaatgctgacctc
tgttacctctccaccgtggattggtccctgatcctggatgccgtgtccaataactacatc
gtgggcaacaaaccccagaaagagtgtggggacctgtgtccagggtcgatggaagagaag
tcgttgtgtgagaagacctccattaacaatgagtacaactaccgctgctggaccacggat
cactgccagaaaatgtgcccgagtgtgtgtggaaagcgagcgtgctcccaggccggggag
tgctgccatgaggagtgcttgggcagctgcactgcccccgacaacgccaccgcctgcgtg
gcctgccgccactactacttcttagggacctgcgtcaccacctgccctcccaacacctac
aagtttgagggctggcgctgcgtggaccgagacttctgcgccaacattctcaacgccgag
agcactgagttcgagggcttcgtgattcacaatggcgagtgcatgcaggagtgcccttcg
gggttcatccgcaacggcaccctgagcatgttctgcgttccgtgcgaaggcccttgcccc
aaagtctgtgaagaagaaaagaagaccaagaccattgactccgtgacgtctgcgcagatg
ctccaaggttgcaccatcttcaagggcaatctgctcattaacatccggcgaggcaataac
atcgcctcagagctggagaacttcatgggtctcattgagatcgtgaccggctatgtgaag
atccgccactcccacgccttggtctccctgtcttttctgaaaaatcttcgccagatttta
ggggaggagcagctcgaagggaattactccttctatgtccttgacaaccagaacctgcag
cagctgtgggactgggaacaccgaaacctgactatcaaagaggggaaaatgtactttgcc
ttcaatcccaaactgtgcgtttccgaaatctaccgcatggaggaagtgaccgggactaag
ggacgccagaacaaaggggacataaacacaaggaacaacggagaacgggcctcctgtgag
agtgatgtgctgcatttcacctccaccaacacgtggaagaatcacatcatcatcacttgg
caccggtaccgccctcctgactacagggacctcatcagcttcaccgtgtactacaaggaa
gccccctataaaaacgtgaccgagtacgatgggcaggacgcctgtgggtccaacagctgg
aacatggtggacgtggacctccctaccaacaaagatgtggaaccaggcattttactgcac
agcctgaagccctggactcagtacgctgtttatgtcaaggcggtgactctgaccatggtg
gagaacgaccacatccgcggggccaagagtgaaatcttgtacattcgcaccaatgcatca
gtgccctccgttcccctggatgttcactcagcatcaaactcttcctcccagttgattgtg
aagtggaaccctccgtccctgccaaacggcaacctgagctactacattgtgaggtggcag
cagcagccgcaggatggctacctttaccagcacaattactgctccaaagacaaaattccc
atcaggaagtatgccgatggcaccattgacattgaggaggtgacagagaaccccaagacg
gaggtgtgtggtggacagaaagggccttgctgtgcctgccccaagactgaggccgagaag
cagactgagaaggaggaagccgagtaccggaaagtcttcgagaatttcctgcataattcc
atctttgtgcccagacccgaaaggaagcggagggacgtcatgcaagttgccaacatgtcc
ctgtccggccgggccaggaacatcacggggggagatggctacaatctcacagacccggat
gagcttgagacagagttccctttctatgagagcagagtggacaacaaggagaggactgtc
atttcaaacctgcggcctttcacgctgtaccgtatcgacatccacagctgcaaccacgag
gccgagcaactgggctgcagcgcctccaacttcgtctttgccaggaccaagcccgcagac
ggagcggatgacattcccgggccagtgacctgggagtccaggcctgaaaactccatcttc
ctcaagtggccagaacctgagaatcccaatggattgatactaatgtacgagatcaaatac
ggatccctagtcgaggatcaacgggagtgcgtttccagacaggactacgagaagtacgga
ggagccaagctgaataggctcaacccaggaaactacacagcccggattcaggctacttct
ctttctggcaacggctcatggacagatccagtgttcttctatgtcccgaccaaaataaga
ccttatgaaaacttcatgcatttgatcatcgctctgcctgtggccgtcctgatggtagcg
ggagggctggttataatgctctatgtctgccacaggaagagaattaacagcaggctgggc
aatggagtgctgtacgcctctgtgaacccggagtacttcagcgcggctgatgtgtatgtt
ccggatgagtgggaggtagcgcgagagaagatcaccatgagccgagagcttgggcaggga
tctttcggaatggtatacgaaggagttgccaagggagtggttaaagatgagcctgaaacc
agagtggccatcaaaaccgtgaacgaggctgcgagcatgcgagaaaggatcgagtttctc
aacgaggcttccgtgatgaaggagtttaattgtcaccatgtggtgcggctgttgggtgtg
gtgtcccagggccagccaacgctggtcatcatggaactgatgacccggggagatctcaaa
agttatctcaggtctctgagaccagaaatggagaacaatccagtcttggcacctccaagc
ctaaccaagatgatccaaatggcaggtgagattgcagacggcatggcatacctcaacgcc
aacaagtttgtccacagagaccttgctgcccggaactgcatggtggctgaagatttcact
gtcaaaatcggagattttggtatgacgagagatatctatgagactgactactaccgcaaa
ggagggaaggggctgctgccggtgcgctggatgtctcccgagtccctcaaggatggcgtc
ttcaccactcattctgatgtttggtccttcggcgtggtcctctgggagatcgccactctg
gctgagcagccctaccagggtttgtccaatgagcaagttcttcgcttcgtcatggagggc
ggccttctggacaagccggacaactgcccggacatgctgttcgagctgatgcgcatgtgc
tggcagtacaaccccaaaatgaggccttccttcctggagatcatcagcagcatcaaggat
gagatggagcctggcttcgaggaggtctccttcttctatagtgaggagaacaagccccct
gagccggaagacctcgacctggagccagagaatatggaaagtgtccctctggacccctct
gcctcctcgtcctccctgccgctgcccgaccgacactcaggacacaaggctgagaacggc
ccaggccccgggatgctgctgctccgcgccagcttcgacgagcgacagccttacgcgcac
atgaacggggggcgcaagaatgagagggccttgcctctgccccagtcctccacctgctga
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integrated database retrieval system
