Echinops telfairi (small Madagascar hedgehog): 101644688
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Entry
101644688 CDS
T08707
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101644688 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
etf03032
]
101644688 (TOP2A)
03036 Chromosome and associated proteins [BR:
etf03036
]
101644688 (TOP2A)
Enzymes [BR:
etf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
101644688 (TOP2A)
DNA replication proteins [BR:
etf03032
]
Eukaryotic type
DNA Topoisomerases
101644688 (TOP2A)
Chromosome and associated proteins [BR:
etf03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
101644688 (TOP2A)
Centrosome formation proteins
Centriole proteins
101644688 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
101644688
NCBI-ProteinID:
XP_045155799
LinkDB
All DBs
Position
Unknown
AA seq
1531 aa
AA seq
DB search
MEVAPLQPLNDNMQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQP
MWVYDEDVGINYRDVTYVPGLYKIFDEILVNAADNKQRDPKMSCIRITIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASKEYKKKFKQTWMDNMGKAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTRDVKVFLNGSTLPVKGFRSYVDMYLKDKVDETGNSLKVIHEQVNHRWEVC
LTMSEKGFQQMSFVNSIATSKGGRHVDYVVDQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKNFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSADCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKSLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKKKQEMAFYSLPEFEEWKS
STSNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPTKDDYTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERAGLHKIFKLQTSLTCNSMVLFDHVGCLKKYDTPLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIVIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSATDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLATFVDELEIVEAKEKEDEQVGLSGKAGKG
KGKKIQKVEVLPSPCGKRVIPRVTTEMKAEAEKKIKRKIKSENTEGSPQEGNMEPDSLKQ
RLEKKQKKELGTKTKKQTTLPFKPIKKGKKRNPWSDSESDMSGDDSNFDVPPREREPRKA
ARSKFTMDLDSDEDFSDFNDTQDEDFTPSDATSPPKAKTSPKHANKGLKTQKSAKSVIDL
DVEDAMDNVPLSSNTPADLPADTEIINPVAKQNVTMKKATTKSQSATSTTGTKKRAAPKG
TKKGPGLNSDESPKKPAPAKSKNPRKRKPSTSDDSDSTFEKIISKAVTNKKSKGEDFQLD
LDSAVAPRAKSGRAKKPIKYLEESDEDDDLF
NT seq
4596 nt
NT seq
+upstream
nt +downstream
nt
atggaggtggcacccctgcagcctctcaacgacaatatgcaaatcagcaaaaccaagaaa
aatgaagacgcgaagaaacggctgtcgatcgagaggatctaccagaagaaaacgcaacta
gagcacattctgctgcggccggacacctacattggctccgtggaactggtgacccagcca
atgtgggtttacgatgaagatgttggcattaactatagggacgtcacctacgttcctggt
ttatacaaaatctttgatgagattctagtcaatgctgcagacaacaagcaaagagaccca
aaaatgtcttgtatcagaatcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctcacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaatatattcagtaccaaattcactgtggaa
accgctagtaaagaatataagaaaaagttcaagcagacatggatggataacatggggaaa
gctggcgaaatggaactcaagccctttagtggtgaagattatacgtgtatcaccttccaa
cctgatttgtctaaatttaaaatgcaaagcttggataaagacatcgttgcactgatggtt
agaagagcctatgatattgctggatccaccagagatgttaaagtctttctcaatggaagt
acattgccggttaaaggattccgtagctatgtggacatgtatttgaaggataaggtagat
gaaactggaaactcattgaaagttatccatgaacaagtaaaccacaggtgggaggtgtgt
ttaacaatgagtgaaaagggttttcagcaaatgagtttcgtcaacagcattgctacgtct
aagggtggcagacatgttgattatgtagttgaccagatagtggctaaacttgtcgatgtt
gtgaagaagaagaacaagggtggtgttgccgttaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacttttgactctcagacaaaggaaaac
atgacattacaggtcaagaactttggatcaacatgccaactaagtgaaaaattcatcaaa
gctgcaattggctgtggtattgttgaaagcatactaaactgggttaagtttaaggcccaa
gtccagttaaacaagaagtgttctgctgtaaaacataacagaatcaaggggattcccaaa
cttgatgatgccaatgatgcaggaggccgaaactctgctgattgtacactcatcctgact
gaaggagactcagctaaaactttggctgtttcaggccttggagtggttgggagagacaag
tatggggtttttccacttcgaggaaaaatgctcaatgttcgagaagcttctcataagcag
atcatggaaaatgctgaaattaacaatatcattaagattgtgggtcttcagtataagaaa
aattatgaagatgaagattcattgaagagtctccgttatgggaagataatgattatgaca
gatcaggaccaagatggctcccatattaaaggtttgctgattaattttattcatcacaac
tggccttctcttctaagacatcgttttctggaggaatttatcactcccattgtaaaggta
tctaaaaagaagcaagaaatggctttctatagccttcctgaatttgaagagtggaagagt
tctacttcaaatcataaaaaatggaaagtcaagtactacaaaggtttgggaaccagcaca
tcaaaagaagctaaggaatactttgcagatatgaaaagacatcggattcaattcaaatat
tctggccctgaagatgatgccgcaatcagtctggcctttagcaaaaaacagatagatgat
cgaaaagaatggttaactcatttcatggaggacaggagacagcgaaagttgcttggtctt
ccagaggattatttgtatggacagactaccacatatctaacctacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggac
ggtttgaaaccgggtcagagaaaggttttgtttacttgcttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagccgggtcagtggctgagatgtcctcttatcaccacggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggcagcaataat
ctgaacctgctgcagcctattggtcaatttggtaccaggttgcatggtggcaaggattct
gctagtcctcgatacattttcacaatgctcagccctttggctcggttgctatttccaaca
aaggatgattacacgttaaagttcttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacctatggtcttaataaatggtgctgaaggaatcggtactggatgg
tcctgcaaaatccctaactttgatgtgcgtgaagttgtgaataacatcaggcggttgatg
gatggagaagaaccactgccaatgcttccaagttacaagaatttcaagggaactattgaa
gaattggcttcgaatcaatatgtgattagcggtgaagttgctattcttaattccacaacc
attgagatctctgagcttcccatcagaacatggacccagacatataaagaacaggttcta
gagcccatgttgaatggtactgagaagacgccacctctcataacagactatcgagaatac
catactgataccactgtgaaatttgttgtcaagatgactgaagaaaagttagcagaggca
gaaagagctggattacacaaaatcttcaagctccaaactagtctcacatgcaactcgatg
gtgctttttgaccacgtaggttgtttaaaaaaatatgacacaccattagatattttaaga
gacttctttgaactcaggcttaaatactatggattacgaaaagaatggcttctaggaatg
cttggtgccgaatctgctaaactgaacaatcaagctcgctttatcttagagaaaatagat
ggaaaaatagtcattgaaaataaacctaagaaagaattaattaaagttctgattcagagg
ggatatgattcagatcctgtgaaagcctggaaagaagctcagcagaaggttcctgatgaa
gaagaaaatgaagagagtgacaacgaaaaggaaactgaaaagagtgattctgccaccgat
tctggtccaacattcaattaccttcttgacatgcccctttggtatctaaccaaggagaag
aaagatgaactgtgcaaactgagaaatgagaaagagcaagaactagaaacattaaagagg
aaaagtccatcagatttgtggaaagaagacttggctacttttgttgatgaactagagatt
gttgaagccaaggaaaaagaagatgaacaagtaggactttctgggaaagcagggaaagga
aaggggaaaaaaatacaaaaggtcgaagttttgccttctccgtgtggcaaaagagtcatc
ccccgggtgaccacagagatgaaggcagaggcagaaaagaaaattaaaaggaaaattaag
agtgaaaatactgaaggaagtcctcaagagggcaatatggaaccagacagtctaaaacaa
agactagagaagaaacagaaaaaagaactaggtaccaagacaaagaaacaaactaccttg
ccatttaaaccaattaaaaaagggaagaagagaaatccctggtctgattcagagtcagat
atgagtggtgacgacagtaactttgatgtacctccacgagaaagagagccccggaaagca
gcaagatccaaattcacaatggatttggattcagatgaagatttctcagatttcaatgac
actcaagatgaagattttaccccatcagatgctactagtccacctaaggccaaaacatcc
ccaaaacatgctaacaaaggactgaagacacagaaaagtgccaaatcagtaatagacctt
gatgttgaagatgctatggataatgtcccactttcttcaaatactcctgctgatttacct
gctgacactgagatcataaatcctgttgctaaacagaatgtgactatgaagaaagcaaca
acaaaaagtcagtctgccacctctaccacaggcaccaagaaaagggctgccccaaaagga
accaaaaagggtcctggtttgaattctgatgaatctcccaaaaagcctgctcctgccaaa
tccaaaaatcctcgcaaaagaaagccgtctacttctgatgattctgactctacttttgag
aaaattatctctaaagcagtgacaaacaagaaatccaaaggtgaggacttccagctggat
ctagactcagctgtggctcctcgggcaaaatctggacgggctaagaaaccgataaaatac
cttgaagaatcggatgaagatgatgatctgttttaa
DBGET
integrated database retrieval system
