Echinops telfairi (small Madagascar hedgehog): 101644765
Help
Entry
101644765 CDS
T08707
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00220
Arginine biosynthesis
etf00330
Arginine and proline metabolism
etf01100
Metabolic pathways
etf04020
Calcium signaling pathway
etf04022
cGMP-PKG signaling pathway
etf04066
HIF-1 signaling pathway
etf04071
Sphingolipid signaling pathway
etf04151
PI3K-Akt signaling pathway
etf04370
VEGF signaling pathway
etf04371
Apelin signaling pathway
etf04611
Platelet activation
etf04915
Estrogen signaling pathway
etf04921
Oxytocin signaling pathway
etf04926
Relaxin signaling pathway
etf04931
Insulin resistance
etf04933
AGE-RAGE signaling pathway in diabetic complications
etf05415
Diabetic cardiomyopathy
etf05417
Lipid and atherosclerosis
etf05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
101644765 (NOS3)
00330 Arginine and proline metabolism
101644765 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
101644765 (NOS3)
04371 Apelin signaling pathway
101644765 (NOS3)
04066 HIF-1 signaling pathway
101644765 (NOS3)
04020 Calcium signaling pathway
101644765 (NOS3)
04071 Sphingolipid signaling pathway
101644765 (NOS3)
04022 cGMP-PKG signaling pathway
101644765 (NOS3)
04151 PI3K-Akt signaling pathway
101644765 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101644765 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
101644765 (NOS3)
04921 Oxytocin signaling pathway
101644765 (NOS3)
04926 Relaxin signaling pathway
101644765 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101644765 (NOS3)
05418 Fluid shear stress and atherosclerosis
101644765 (NOS3)
05415 Diabetic cardiomyopathy
101644765 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101644765 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
101644765 (NOS3)
Enzymes [BR:
etf01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
101644765 (NOS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
DUF6285
Motif
Other DBs
NCBI-GeneID:
101644765
NCBI-ProteinID:
XP_004702531
LinkDB
All DBs
Position
Unknown
AA seq
1198 aa
AA seq
DB search
MGNLKSVAQEPRPPCGLGLGFGLCSKQDPVSPASEPSQAPAPVPPPSPDHSPPLTQSPER
PKFPRVKNWEEGSITYDTLSSQAQQVGPCTPRHCLGSLVFPRKLQSQASLDPASPERLLR
QARDFIHQYYSSIRRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCV
GRIQWGKLQVFDARDCSSAQEMFTYICNHIKYGTNRGNIRSAITVFPQRTPGRGDFRIWN
SQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGHGRFDVLPLLLQAPDEPPEVFPL
PPELVLEVPLEHPTLEWFAALGLRWYALPAVANMLLEIGGLEFPAAPFSGWYMSTEIGTR
NLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDHHAATA
SFMKHLENEQKARGGCPADWAWIVPPLSGSLTPVFHQEMVNYFLSPAFHYQPDPWKGSTA
KGTGITRKKTFKEVANAVKISASLMGTLMAKRVKATILYGSETGRAESYAQQLGRLFRKA
FDPKVLCMDEYDVVSLEHETLVVVVTSTFGNGDPPENGESFAAALMEMSSPYNNSPRPEQ
HKSYKMRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFAR
AVDTRLEELGGERLLQMGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAARDIFS
PKWSWKRQRYRLSAQAKDLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATILVRLDT
EGQQGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPPTEAIAVEQLEKGSPGGPPPGWV
RDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPSEQQELEALSQDPRHYEEWKW
FRCPTLLEVLEQFPSVALPAALLLTQLPLLQPRYYSVSSAPSAYPGEVHLTVAVLAYRTQ
DGLGPLHYGVCSTWLSQLKTGDAVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFW
QERLHDIESKGLQPAPMTLVFGCRCSQLDHLYSEEVRDAQQRGVFDQVLTAFSREPDTPK
TYVQDLLRTELASEVYRVLCLERGHVFVCGDVTMATNVLQTVQRILAAEGEMELDEAGDV
IGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQESQLRSAVPWAIDQPGLDIPCP
NT seq
3597 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtagcccaggagcccagaccaccctgtggcctgggcctgggc
tttgggctgtgcagcaagcaggacccagtctcgccagcctcagagcccagccaggcgcca
gcacccgtgcctccaccttcgccggatcacagccccccgttaacccagagcccggagagg
cccaagttccctcgcgtgaagaactgggaagaggggagcatcacctacgacaccctgagt
tcccaggcgcagcaggttggaccctgcaccccaagacactgcctgggctccctggtgttt
ccgaggaaactacagagccaagcatccctggaccctgcatcccctgagaggcttctgagg
caggcccgggacttcatccaccagtactacagctccatcaggaggagcggctcccaggcc
cacgagcagcgacttcaggaggtagaagctgaggtggcagccacgggcacctaccagctt
cgggagagtgaactggtgttcggggccaagcaggcctggcgcaacgccccccgatgtgtt
ggccgcatccagtggggcaagttacaggtgtttgacgccagagactgcagctctgcccag
gagatgttcacctacatctgtaaccacattaagtatggcaccaaccgcgggaacattcgc
tcggccatcacggtgttcccacaacgcacccctggccgtggagactttcgcatctggaac
agtcagttggtgcgctatgcaggctacaggcagcaggatggctctgtgcggggcgaccct
gccaatgtggagatcactgagctctgcatccagcatggctggaccccaggccacggccgg
ttcgatgtgctgcccctgctgctccaggcccccgatgagccccccgaggtcttccctctg
ccccccgaactggtcctcgaggtgcctctggaacaccccacgctggagtggtttgcagcc
ctgggcctgcgctggtatgccctcccggcagtagccaacatgctgctggaaattgggggg
ctggagttccccgcggctcctttcagcggctggtacatgagcactgagattggcactcgc
aacctgtgtgacccccaccgctacaacattctagaagatgtggccgtctgcatggacctg
gacacacggacaacttcgtccttgtggaaggacaaggcggctgtggaaattaacttggcg
gtgctgcacagttaccagctggccaaagtgaccattgtggaccaccatgctgctacagcc
tccttcatgaagcacctggagaatgagcagaaggcgaggggcgggtgcccagctgactgg
gcctggatcgtgccccctctctctggcagcctcacacctgtcttccatcaagagatggtc
aactatttcctgtccccggctttccactaccagccagatccctggaagggaagcacagcc
aagggcacaggcatcaccaggaaaaagacctttaaggaagtggccaacgcagtgaagatc
tcagcctcgctcatgggcactctgatggcaaagagagtgaaggcaaccatcctgtatggc
tcggagaccggccgggcggagagctacgcccagcagctggggaggctcttccgcaaggct
ttcgatcccaaggtcctgtgcatggatgaatatgacgtggtgtccctggagcatgagacg
ctggtggtggtggtgaccagcacgtttggaaatggcgacccacccgagaatggcgagagc
tttgcggctgcgctgatggagatgtccagcccctacaacaactctcctcggccggaacag
cacaagagttacaagatgcgtttcaacagtgtctcttgctcagaccccctggtctcttcc
tggcggcggaaaagaaaagagtccagtaacacagacagtgctggggcgctgggcaccctc
cggttctgcgtgttcgggctgggctcccgggcatatcctcacttctgtgccttcgcgcgt
gctgtggacactcggctggaggagctgggtggagagcggctgctgcagatgggccagggg
gatgagctgtgtggccaggaggaagccttccgcggctgggcgcaggctgccttccaggcc
tcctgtgagactttctgtgtgggagaagacgccaaggctgccgcccgggacatattcagc
cccaagtggagctggaagcgccagagatacaggctgagtgcccaggccaaagacctccag
ctgttgccaggcctgatccatgtacataggaggaaaatgttccaagcgacggtcctttcg
gtggagaacctgcaaagcagcaagtccacccgggccaccatcttggtgcgcctagacaca
gaaggccagcaggggttacagtaccagccaggggaccacataggcgtgtgcccgcccaac
cggcccggtctcgtcgaggccctgctgagccgtgtagaggacccaccaccacccacagaa
gctatcgcagtggagcagctggagaagggcagtcctggtggtccaccccccggctgggtg
cgggaccccagactgcccccgtgcacgctgcgccaggctctgacattcttcctggacatc
acatccccacccagccctcgccttcttcgactgctcagcaccctagctgaagagcccagc
gaacagcaggagctggaggccctcagccaggacccccggcactatgaggaatggaagtgg
ttccgctgccccacgctactggaagtgctggagcagttcccatcggtggccttgcccgcc
gccttgctcctcacccagctgcccctgctgcagccccggtactactcagtgagctcagca
cccagtgcctacccgggggaagtccacctcacagtagctgtgctggcatacaggacccaa
gatgggttgggcccactgcactatggcgtctgctccacctggctgagtcaactcaagaca
ggagacgctgtgccctgcttcatcaggggggccccctccttccggctgccgcctgacccc
agcttgccctgcatccttgtgggacctggcacgggtattgcccccttccggggattctgg
caggagaggctgcacgacattgaaagcaaagggctgcagcctgcccccatgaccttggtg
tttggctgccgatgctcccaactggaccacctctacagtgaggaggtgcgagacgctcag
cagcgcggggtgtttgaccaagttctcaccgctttctcccgggaaccggacacccccaag
acctacgtgcaggacctcctgcggactgagctggcctccgaggtgtaccgcgtgctgtgc
ctggagcgtggccacgtgtttgtctgcggcgacgtcaccatggcgaccaacgtcctacaa
acggtgcagcgcatcctagcggcggagggggaaatggagctggacgaggccggcgacgtc
atcggcgtgctcagagatcagcaacgctaccacgaggacatttttgggctcaccctgcgc
acccaggaggtgaccagccgcattcgcacccagagcttttccttgcaggagtcgcagttg
cggagcgcagtaccctgggcgattgaccagcctggtctagacatcccctgtccttga
DBGET
integrated database retrieval system
