Echinops telfairi (small Madagascar hedgehog): 101649302
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Entry
101649302 CDS
T08707
Symbol
ATM
Name
(RefSeq) serine-protein kinase ATM
KO
K04728
serine-protein kinase ATM [EC:
2.7.11.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01524
Platinum drug resistance
etf03440
Homologous recombination
etf04064
NF-kappa B signaling pathway
etf04068
FoxO signaling pathway
etf04110
Cell cycle
etf04115
p53 signaling pathway
etf04210
Apoptosis
etf04218
Cellular senescence
etf05165
Human papillomavirus infection
etf05166
Human T-cell leukemia virus 1 infection
etf05170
Human immunodeficiency virus 1 infection
etf05202
Transcriptional misregulation in cancer
etf05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
101649302 (ATM)
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
101649302 (ATM)
04068 FoxO signaling pathway
101649302 (ATM)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
101649302 (ATM)
04210 Apoptosis
101649302 (ATM)
04115 p53 signaling pathway
101649302 (ATM)
04218 Cellular senescence
101649302 (ATM)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101649302 (ATM)
05206 MicroRNAs in cancer
101649302 (ATM)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101649302 (ATM)
05170 Human immunodeficiency virus 1 infection
101649302 (ATM)
05165 Human papillomavirus infection
101649302 (ATM)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101649302 (ATM)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101649302 (ATM)
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
etf03032
]
101649302 (ATM)
03036 Chromosome and associated proteins [BR:
etf03036
]
101649302 (ATM)
03400 DNA repair and recombination proteins [BR:
etf03400
]
101649302 (ATM)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101649302 (ATM)
Protein kinases [BR:
etf01001
]
Serine/threonine kinases: Other
PIKK family [OT]
101649302 (ATM)
DNA replication proteins [BR:
etf03032
]
Eukaryotic type
DNA Replication Termination Factors
Other termination factors
101649302 (ATM)
Chromosome and associated proteins [BR:
etf03036
]
Eukaryotic type
Meiosis-specific proteins
DSB formation-related proteins
101649302 (ATM)
DNA repair and recombination proteins [BR:
etf03400
]
Eukaryotic type
Check point factors
Other check point factors
101649302 (ATM)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3_PI4_kinase
FAT
FATC
M-HEAT_ATR
Motif
Other DBs
NCBI-GeneID:
101649302
NCBI-ProteinID:
XP_045153674
LinkDB
All DBs
Position
Unknown
AA seq
2710 aa
AA seq
DB search
MLHILNRLQDVFNENTQFLEISQSYTTTQREFSDCSTPCKRRRIESGWEVIKDHLQKSQN
DFHLVPWLQITTQLISKYPTSLPNCELTPLLIILSQLLPQQRRGERTPYVLRCLMEVALC
QGKTLNLESSQKSDLLKLWMKICSITFRGISSEQIQVENFGLLGAIIKGNLVEVDREFWQ
LFTGSACKPSGPAVCCLAVALTIAVIPERVTAGREQHLCEVNRSFSLRERIMKWLLFYQL
EDDLEDLTELPPVLLSKFPHLSVEKILVSLTLKNCKAAMIFFQSVPECEQHQKDKEESSF
SQVEELFLQTTFDKMDFLTVVKECATEKHRSSPGFSVHQSLKEALDHYLLALSEQLLSNY
SPETADSDALVRCSSVLVGVLGCYCYVGVIAEEEAHKSELFQKAKSLMQCAGESITLFKN
KTNEDPRIDSLRNMMLLCISCLCNCTKHSPNKIASGFFLRLLTSKFMNDIADICKILSSF
IKKPFDSGEVETVEDDPDESGMEVENQSPLNLFGDYSTCPVSDANESGESQSNTGAMNPL
AEEYLSKQDLLFLDMLKFLCMCVTTAQTNTVSFRAADIRRKLLMLIDSSTLDLTKSLHLH
MYLVLIKELPGEDTPLPIEDVVELLKPLSNVCSLYRRDQEVCKTILNHILHIVTNLGQGH
VDNEHTRDAQGQFLTVMGAFWHLAKEGKCTASVRMALVRCLKALLEADPYSKWAILNVMG
KDFPVNEVFPQFLADNHHQVRMLAAGSINRLFQDMKQRESSKLLKALPLTRQRTAFQNAY
QQARDGMRESRNAENLELSDELHNRKAVLLMMVAVVLHCSPVCEKQALFALCKSVKENGL
EPLLIKKVLEKVSEIFGYRHLEDFMTSHLDYLILEWLNQQETERTLSSFPFILLNYTCVE
DFYRSCYKALIPHLVIRSHFDEVKSIANQIQEDWKVLLTDCFPKVLVNILPYFAYESTGD
SEMSQQRETAVNVYDMLKDESLLGKQIDHLFISNLPEIVFELLMTLHEPAKSDGTQNTDL
CGFSGDLDPAPNPPYFPSHVIKATFAYISNCHKTKFKSILEILSKSPDSYQKILLAICEQ
AAETNNVYKKKRILKIYHLFVSLLLKEIKSGLGGAWAFVLRDVIYTLIHYINKRPSHFMD
VSLRTFSLCCDLLSRVCQTAVAFCKDALESHLHVIVGTLIPLVNGQLEVQEQVLDLLKYL
VIDNKDNENLYLTIKLLDPFPDHVVFKDLRITQQKIKYSRGPFLLLEEINHFLSVSVYDA
LPLTRLEGLKELRRQLEQHKDQIKGLTRASQENPQDGILVKLVVSLLQLSKMAVNHPGER
EVLEAVGSCLGELGPIDFSTIAIQHSKDASYNKALELFEDKELQWIFILLTHLNNTLVED
CVKVRSAAATCLKSILATKTGHNFWEVYKTTTDPMLAYLQPFRASRKKFLEVPRLDRRSP
FEDLDETSLWIPQNGNHDVWIKTLTCAFLDSGGIKSEVLQLLKPMCEVESDFCQTVLPYL
IHDILLQDTSECWRNLLSVHIQGFFSSSFRQSSQTSRSTTPANLDSDSEHFVRGGLDKKS
QRTMLAVVDYMRRQKRPLSGTVYDDAFWLDLNYLEVAKVAQSCAAHFTALLYAEIYADQK
NMGDQEKRSPTLEEGSQSTTISSLSEKSKEETGISLQDLLLEIYRSIGEPDSLYGCGGGK
VLQPLTRIRTYEHEAMWGKALITYDLETAISSSTRQAGIIQALQNLGLCHILSTYLRGLD
HENKESCAELQELHYQAAWRNMQWDHCSSVNKGIEGTSYHESLYSALQSLRDREFSTFYE
SLKHARVKEVEELCKGSLESVYSLYPTLSRLQAIGELENIGELFSRSLAERQLSEVYGKW
QKHSQLLKDSDFRFQEPIMALRTVVLELLTEKAMESAQRQCFKDILTKHLVQLSTLARTF
QNTQLPERAIFQIKQYNSTSCGVSEWQLEEAQVFWAKKEQSLALSILKQMIKKLGDSCTE
EPTLKLLYTECLRVCGNWLAETCLESPSVIMQTYLEKAVEVVGNYDGGSSDELRNGKTKA
FLSLARFSDTQYQRIENYMKSSEFENKQALLRKAKEEVGLLREHKIQTNRYTVKVQRELE
LDECALRALKEDRKRFLYKAIENYINCLLSGEEHDMWVFRLCSLWLENAGASEVNGMMKR
VGMKIPSHKCLPLMYQLAARMGTKMMGGLGFHEVLDNLISRISMDHPHHTLFIILALANA
NKDEFLTKPEAAKRSRITKTTPKQNSQLDEDRAAAARKIIHVIKSRRPQMVRNVEALCDA
YILLANLDATQWKMQRKGINIPTDQPITKLKNLEDVVVPTMEIKVDPTGKYESLVTIQSF
RAEFRLAGGINLPKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETR
KRKLTICTYKVVPLSQRSGVLEWCTGTVPIGDFLVHSEDGAHKRYRPQDLSAYQCQKKMM
DVQKKSFEEKYETFMDICQNFQPVFRYFCMEKFLDPAVWFEKRLAYTRSVATSSIVGYIL
GLGDRHVQNILINEQSAKLVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGV
FRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDWTMNPLKALYLQQRPEDETELNSTLNT
VDQECKQNLSGIDQSFNKVAERVLMRLQAKLKGVEEGTVLSVGGQVNLLIQQAMDPKNLS
RLFPGWKAWV
NT seq
8133 nt
NT seq
+upstream
nt +downstream
nt
atgttgcacatactgaatagactacaggatgtttttaatgaaaatacccaatttctggag
atttctcagtcttatactactacacaaagagaatttagtgactgcagtacaccttgcaaa
aggaggagaatcgaatctggctgggaagtaattaaagatcatcttcagaaatcacagaat
gattttcatcttgtgccttggttacagattacaacacaattaatatcaaagtaccctaca
agtttgcctaactgtgagctaacaccattactgataatactctcccagcttctacctcaa
caacgacgtggggaacgcacaccatacgtgttacgatgccttatggaagttgctctgtgt
caaggcaagactttaaacctcgaaagctctcaaaagtcagatcttctgaagctctggatg
aaaatttgttctattacctttcgaggtataagttctgaacaaatacaagttgaaaacttt
ggcttacttggagccataattaaaggcaatctagttgaagttgatagagagttttggcag
ttatttactgggtcagcctgcaaaccttcaggccctgcagtatgctgcttggcagtggca
ctcaccatagctgtaattcctgaaagagtaacagcaggccgagagcagcatctctgtgaa
gtgaatagaagtttttcattaagagaaaggatcatgaaatggctcttattctatcagtta
gaggatgacttagaagaccttaccgagctgccccccgttcttctcagtaagtttcctcac
ctttcagtggagaaaattcttgtgagtctcactctgaaaaactgtaaagctgcaatgatt
tttttccaaagtgtcccagaatgtgagcaacaccaaaaagataaagaagaatcctcattt
tcacaagtagaagaactgtttcttcagacaacttttgacaagatggattttttaaccgtt
gtgaaagaatgtgctacagaaaagcaccgatccagtcctggattttctgtccaccagagt
ctcaaggaagcactggatcactatcttctagcattatcagaacagctgctatctaattac
tcacccgagactgcagattcagacgcgcttgtccggtgttccagtgttttggtgggtgtc
cttggctgctattgttacgtgggtgtaatagctgaagaggaagcacataagtcagaatta
ttccaaaaagccaagtccctaatgcagtgtgcaggggaaagtatcactctgtttaaaaat
aagacaaatgaagaccctagaattgactcgttaagaaacatgatgcttctgtgtataagc
tgcttatgcaactgtaccaagcacagtccaaataagattgcatctggcttttttctgaga
ttgttaacatcaaagttcatgaatgacattgcagatatttgtaaaattttatcatccttt
atcaaaaagccatttgattctggagaagtagagacagtggaagatgatcctgatgaaagt
ggaatggaagtggagaatcagtcacctctgaatctgtttggcgactactctacttgtcct
gttagtgatgcaaatgaatctggagagagccaaagtaatactggtgctatgaacccttta
gcagaagaatatttgtcaaagcaagatctactgtttttagacatgctcaagttcttgtgt
atgtgtgtaactactgcccagaccaacacagtgtcatttagagcagctgatattcggagg
aaactgttaatgttaatagattctagcacactagatcttacaaaatctcttcacctacac
atgtatttagtacttataaaggagctcccaggagaagacactcccttgccaattgaagat
gttgttgagcttctgaaacctctatctaatgtgtgttctttgtatcgccgtgaccaagaa
gtttgcaaaaccattttaaaccacatccttcatatagtaacaaacctgggacaaggccat
gtggacaatgagcacaccagggatgctcaagggcagttcctaacagtgatgggagcattt
tggcacttagccaaggagggaaaatgcacagcatctgtgagaatggcactagtaagatgc
cttaaggctctgcttgaggctgatccttattcaaaatgggcgattctcaatgtaatggga
aaagacttccctgtaaatgaagtattcccacaatttcttgctgataatcatcaccaagta
cgaatgttggctgcagggtcaatcaacagattattccaggatatgaagcagagagagtct
tccaagttattgaaagcccttcctctgacgcgtcaacggacagcgtttcaaaatgcatac
cagcaagcccgggacgggatgagagagtcccgcaatgccgagaacctggaactttcagat
gagcttcataatagaaaagctgtcttactgatgatggtagctgtggttttacactgtagc
cccgtctgtgagaaacaagccttgtttgctctctgcaaatctgtgaaagagaatggatta
gagcctctcctcattaaaaaggttttagagaaagtgtctgaaatttttggctatagacac
ctggaagatttcatgacttctcacttagattatctaattttggagtggctcaatcaacaa
gaaactgaacgcaccttatcttctttcccttttattttactaaactacacatgtgttgag
gatttctacagatcttgctataaggctttgatcccacatctggtgattagaagccatttt
gatgaggtcaagtccattgcgaatcagattcaagaggactggaaagttcttctaacagac
tgcttcccaaaggttcttgtgaatatccttccatattttgcctatgagagtacaggagac
agtgagatgtcacagcaacgagagactgctgtcaatgtgtatgacatgctcaaagatgag
agcttgttagggaaacagattgatcatttattcattagtaatttaccagagattgtgttc
gaattattgatgacattacatgaaccagcaaaatctgatggcacccaaaacactgacctc
tgtggcttttcaggggatttggatcctgctcctaatccaccttattttccatcgcatgta
attaaggcaacatttgcctatatcagcaattgccataaaaccaagtttaagagcatctta
gaaattctttccaaaagccctgattcctatcaaaaaattcttttagctatatgtgaacaa
gcagctgagacaaataatgtatataaaaagaagagaattcttaaaatatatcacctgttt
gttagtttattactgaaggagataaaaagtggcttaggaggagcttgggcctttgttctt
cgagatgttatttatactttgatccactatatcaacaaaaggccctctcacttcatggat
gtgtccttacgcaccttctccctttgttgtgacctcttaagtcgggtttgccagaccgca
gtggcgttctgcaaggatgctttagaaagccatctccatgttatcgttggtactcttatc
cccctggttaatggtcaattggaagttcaggaacaggtcttggacttgttaaaataccta
gtgatagataacaaggataatgaaaacctgtatctcacaattaagcttttagatcctttt
cctgaccacgttgtttttaaggatttgcgtattacgcagcagaaaatcaaatatagtaga
ggaccatttttactcttggaggaaattaatcatttcctctcagtgagtgtttatgatgcg
ctacctttgacaagactcgaaggactgaaggagctccgaaggcagctggagcagcataaa
gatcaaatcaagggtctcacgagagcttctcaggaaaacccacaagatggcattctggtg
aagctggtggtgagcttgttgcagttatccaaaatggcggtaaaccaccctggggaaaga
gaagttttagaggctgttggaagctgcttgggagagttgggccctatcgatttctccacc
atagccatacaacatagtaaagatgcatcttataataaggcccttgagttatttgaagat
aaagaacttcagtggattttcatactgctgacccacctgaataataccctagtagaagat
tgtgtcaaagttcgatcagctgctgctacctgtttgaaaagcattttagccacgaagact
ggacataatttctgggaggtatacaagacaacgactgatcccatgctcgcctatctgcag
cctttcagagcatcaagaaaaaagtttttagaagtacccagactggacagaagaagtcct
ttcgaagacctggatgagacaagtttgtggattcctcaaaacggaaatcatgatgtttgg
ataaaaacactgacttgtgcttttttggacagtggaggcataaaaagtgaagttcttcag
ttgctaaagcccatgtgtgaagtggaaagtgacttttgtcagactgtgctaccgtacttg
attcatgatattttgctgcaagatacaagtgagtgctggaggaatctgctgtctgtgcat
attcagggattcttcagcagttctttcagacagtcctcacaaaccagcaggtccaccacc
ccggcaaacttggattcggactcagaacactttgtccgaggcggtttggataagaaatca
caaagaactatgcttgctgttgtggactacatgagaagacagaagcgacctctctcagga
accgtttacgatgatgctttctggctggatttgaactatctagaagttgccaaagtggct
cagtcttgtgcggctcactttacagcattgctttatgcagaaatctatgccgatcagaaa
aacatgggtgatcaagagaaaaggagccctacattggaagaaggaagccaaagtacaact
atttctagtttgagtgaaaagagtaaagaagaaactggaataagtttacaggatcttctc
ctagagatctacagaagcataggagagccagatagcctgtatggttgtggtggaggaaaa
gtgttacaaccactcactcgaatacgaacatatgaacatgaggcaatgtggggtaaagct
ctgataacatatgaccttgagacagcaattagctcatccactcgccaggccggaattatt
caggccctgcagaatctgggactctgccacattctctccacctacttaagaggattagat
catgaaaataaagagtcgtgtgctgagcttcaggaactgcattaccaagctgcgtggagg
aacatgcagtgggaccactgcagttcggtcaacaaaggaattgaaggaaccagctaccac
gaatccttgtacagcgctctgcagtctctaagagacagagagttttccaccttttatgaa
agtctgaaacatgccagagtgaaagaagtggaagaattgtgtaagggcagccttgagtct
gtatattcactctacccaactctaagcagattgcaggccatcggtgagctggagaacatt
ggagagcttttctcaaggtcactcgccgagcggcagctctcggaagtgtacggtaagtgg
cagaagcactcgcagctcctgaaggacagtgattttcgcttccaggagcccatcatggct
ctgcgcacagtcgttttggagctcctgacggaaaaggcaatggagagcgcccagaggcag
tgttttaaagacatcctcaccaagcaccttgtacagctgtccacactggcccgaacattc
cagaatacccagctccctgaaagggctatatttcaaattaagcagtataattcaacaagt
tgtggagtctctgagtggcagttggaggaagcgcaagtattctgggcgaagaaggaacag
agtcttgctctgagtattctcaagcaaatgatcaagaaattgggtgacagttgtacagag
gaacccaccctcaaactgctgtacacggaatgcttgagggtttgtggcaactggttagca
gaaacttgcttagaaagcccctcagtcatcatgcagacctatctggaaaaggcagtggaa
gttgttggaaattacgatggaggaagcagtgatgagctgagaaatggaaaaacaaaggcg
tttctctcgttagcacggttctcagatactcagtaccagagaattgaaaactatatgaag
tcatccgaatttgaaaacaaacaagctcttctgaggaaggctaaagaggaagtgggcctc
ctcagggaacataaaattcagaccaacaggtacacagtcaaggttcagcgagagctcgag
ctggatgaatgtgcactccgggctctgaaggaagatcgtaagcgcttcttatataaagcg
attgaaaattacatcaactgcttattaagtggagaagagcatgacatgtgggtgttccga
ctctgttctctctggctggaaaatgctggcgcttctgaagtcaatggcatgatgaagcgc
gttggaatgaagattccgtcacataaatgtttgcctcttatgtaccagttggctgctaga
atggggaccaagatgatgggaggcctagggtttcatgaggtcctcgacaatctcatctcc
agaatttcaatggatcatccccatcatactttatttattatactggccttagcaaatgcc
aataaagatgaatttctgaccaaaccagaggcagcaaaaaggagtagaataaccaaaacc
acacccaaacaaaactctcagcttgatgaggatagagctgcagctgcacgtaaaataata
catgttatcaaaagtaggagaccccagatggtcaggaatgttgaggcactttgtgacgct
tatattctgttagcaaacttagatgccactcagtggaagatgcagagaaaaggcataaat
attccaacagaccagccaattactaaattgaagaatttagaagatgttgttgtccccact
atggaaatcaaggtggaccccacaggaaaatatgagagtctggtgacgatacagtcattc
agagcagaatttcgtttagcaggaggtataaatttgccaaaaataatagattgtgtaggc
tctgatggcaaggaaaggcgacagcttgtcaagggccgcgatgacctgcgacaagatgct
gtcatgcagcaggttttccagatgtgtaatacattactgcagagaaacacggaaaccaga
aagaggaaactaaccatctgcacatataaggtggtccccctgtctcagcgaagtggggtt
ctggagtggtgcacagggaccgtgcccattggcgactttctggttcacagtgaagacggt
gctcataaaagatacaggccccaggatctcagtgcgtaccagtgccaaaagaaaatgatg
gatgtgcaaaagaaatcttttgaggagaagtatgaaactttcatggatatctgccaaaat
tttcagcccgttttccgttacttctgcatggaaaagttcttggatccagctgtttggttt
gagaaacgattggcttatactcgcagtgtggctacttcttcgatcgttggttatatactt
ggacttggtgatagacatgtacaaaatatcttgataaatgaacagtcagcaaaacttgta
catattgatctcggggttgcgtttgaacagggtaaaattcttcctactcctgaaacggtt
cctttcagactcaccagagatattgtggacgggatgggcatcactggggtggaaggcgtc
ttcagaaggtgctgtgagaaaacgatggaagtcatgaggagctctcaggaaaccctcctg
accattgtagaggtcctcctctatgatcctctctttgactggaccatgaatccattgaaa
gctttgtatttacagcagaggcccgaagatgaaaccgagctcaactccactctgaataca
gttgaccaagaatgcaaacaaaatctcagtggcatcgaccagagtttcaacaaagtagct
gaacgtgtcttgatgagactccaagcgaagctgaaaggcgtggaggagggcactgtgctc
agcgtggggggacaggtgaacctgctcattcagcaggccatggaccccaaaaatctcagc
cggcttttcccaggatggaaagcatgggtgtga
DBGET
integrated database retrieval system
