Echinops telfairi (small Madagascar hedgehog): 101650459
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Entry
101650459 CDS
T08707
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf03030
DNA replication
etf03410
Base excision repair
etf03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
101650459 (POLE)
03410 Base excision repair
101650459 (POLE)
03420 Nucleotide excision repair
101650459 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
etf03032
]
101650459 (POLE)
03400 DNA repair and recombination proteins [BR:
etf03400
]
101650459 (POLE)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
101650459 (POLE)
DNA replication proteins [BR:
etf03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
101650459 (POLE)
DNA repair and recombination proteins [BR:
etf03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
101650459 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
Motif
Other DBs
NCBI-GeneID:
101650459
NCBI-ProteinID:
XP_045152700
LinkDB
All DBs
Position
Unknown
AA seq
2237 aa
AA seq
DB search
MDLRFGFERLKEPGEKTGWLINMHPTEVLDEDKRLVSAVDYYFIQDDGSRFKVALPYKPY
FYIATRKGCEREVSSFLSKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDL
VKVRKEISPAVRKNREREHANDTYTSMLSSVLQGGGVINDEEEASKKIADQMDNIVDMRE
YDVPYHIRLSIDLKIHVAHWYNIRYRGSASPVEITRRDDLVERPDPVVLAFDIETTKLPL
KFPDAETDQIMMISYMIDGQGYLITNREIVSEDIDDFEFTPKPEYEGPFCVFNEPDEVHL
IQRWFEHVQETKPTIMVTYNGDFFDWPFVEARASVHGLSMYQEIGFQKDGQGEYKAPQCI
HMDCLRWVKRDSYLPVGSHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDA
VATYYMYMKYVHPFIFALCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIVFPNKQEQE
FNKLTDDGHVLDAETYVGGHVEALESGVFRSDIPCRFRMNPVAFDFLLQRVEKTLRHAVE
EEEKVPIEQVTNFQEVCDQIKSRLISLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPS
AMVDEATCAACDFNKPGANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGP
ARAFHELSREEQAKYEKRRLADYCRKAYKKLHVTRVEQRLTTICQRENSFYVDTVRAFRD
RRYEFKGLHKVWKKKLSAAVEAGDAAEVKRCKNMEILYDSLQLAHKCILNSFYGYVMRKG
ARWYSMEMAGIVCFTGANIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVVKTTNV
KKPKVTISYPGAMLNIMVKEGFTNHQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILP
ASKEEGKKLKKRYAVFNEDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVY
GSVAKVADYWLDVLYSKAANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEF
LGDQMVKDAGLSCRYIISRKPEGSPVTERAIPLAIFQAEPMVRKHFLRKWLKSSSLQEFD
IRTILDWDYYIERLGSAIQKIITIPAALQQVKNPVPRVRHPDWLHKKLLEKNDAYKQKKI
SELFVVEGKRQVVMNQAPEGSPSPRAPDMEDIGLAKPPRVAVPVVTKRKRVLLEESQEES
QELTVSWQEVLGQPPPLGTTQEEFLVWLRFHKKKWQLQARQRLARRKRQRHECTEDTLRA
GVRREGPAMGLGSFLQRTARSILDLPWQIVQICETSQPGLFRLWAVIGSDLHCIKLSIPR
VFYVNKQVAKAEEGPSCRKVNRVLPRATVVHNLYEYSVPEDMYQEHINKINTELSAPDVE
GVYETQVPLLFRALVQLGCLCVVNKQLVRHLSGLEVNTFALEHLEMRSLAQFSYLEPGSI
RHLYLYHHLQGHKALFGVFFPTQRRASVFVLDTVRSNQMPSLGTMYSSAHGLLLEQLGPD
FLPPPKHTFEVRAETDLKTICRAIQRLLLAYKEERRGPTLIAVQSSWELRQLVGEVPVLE
EFPLVPVRVAEKVSYAVLDWQRQGARHMIRHYLHLDTCLSQAFEMSRYFHIPVGNLPEDI
STFGSDLFFARHLQRHSHLLWLSPTSRPDLGGREADNSRLVMELDDRTMVEINSSGCYST
VCVELDLQNLAVNTVLQSHRVNDMEGAASVGISFDAIPQASLEDMITGNQGACMPASYDE
TALCSSTFRVLKSMVVGWVKEITQYHNVYADNQVMHFYRWLRSPSSLLHDPALHRTLYSM
MKKLFLQLIAEFKRLGSSIVYANFNRIILCTKKRRIEDALAYVEYITNSIHSKELFRSLT
LSFSRCWDFLLWMDPSNYGGVKGKVPSSVHRGQQRASPGGEDEEEEEEDAADEVEESLEE
ARVEDLLENKWNILQYLPQAASCQSYFLMIVSAYIVAVYHSMKEELRRSAPGSTPVKRRG
ASQFSQETEATAGSLPGMITFSQDYVANELTQNFFTITQKIQKKVTGSRNSTEPSEMFPQ
LPGSHLVLNNPALEFTKYVCKVLSLDTNITNQVNKLRRDLMRLVGVGEFSPEAQFQDPCR
SYVLPEVICHSCNFCRDLDLCKDSAFSQDGAILPRWLCPNCEEPYDPTVIEAALVEALQK
KLMAFMQQDLVCLKCGAVKDTHMPIHCSCAGDFALTIHTAAFLEQMGIFRNIAQHYGMSY
LLETLEWALRKTPPPCC
NT seq
6714 nt
NT seq
+upstream
nt +downstream
nt
atggatctgcggttcggctttgaaagactgaaggagcctggggagaagacaggctggctc
atcaacatgcatcctactgaagtgttagatgaagacaagcgcctcgtcagtgcagtagat
tactactttattcaagacgatggaagcagatttaaggtggcattaccctacaagccatat
ttctacattgcaactaggaagggttgtgaacgagaagtttcatcttttctctccaagaag
tttcagggtaaaattgctaaagtggagactgtccccaaagaagatctggacttgccaaat
cacttggtgggcttgaagcggaattacataaagctgtctttcaacacggtggaggacctg
gtgaaagtgaggaaggagatctcccctgcggtgcggaagaaccgagagcgagaacacgcc
aacgacacctacacgtctatgctctccagtgttctgcaagggggtggagtaattaacgat
gaagaggaagcctctaaaaagatagctgaccagatggacaacatcgtagacatgcgggag
tacgacgtcccgtaccacatccgcctctccatcgacctgaagatccatgtggctcactgg
tacaacatcagataccggggtagtgcctctcctgtggaaatcacccgccgagatgacctc
gttgaacggcctgaccctgttgttttggcatttgacattgaaactaccaaattacccctc
aagttccctgatgctgagactgaccagattatgatgatttcatacatgatcgacgggcag
ggctacctgatcaccaaccgggagattgtgtcagaagatatcgacgactttgagttcacc
cccaagccagagtatgaaggaccattctgtgtcttcaatgagcccgatgaggttcatctc
atccagaggtggtttgagcatgtgcaggagaccaagcccactatcatggtgacctacaac
ggagacttctttgactggccatttgtggaagcccgagcgagcgtgcatggcctgagcatg
taccaggagatagggttccagaaggacggccagggggagtacaaggccccccagtgcatc
cacatggactgcctccggtgggtgaagagagacagctacctccctgtgggcagtcacaac
ctcaaggcggctgccaaagctaagctgggctatgaccctgtggagctggaccccgaggac
atgtgccgcatggccaccgagcagccccagaccctggccacatactccgtgtcagacgcc
gtggccacgtactacatgtacatgaaatacgtgcaccccttcatctttgcactgtgtacc
atcatccccatggagcctgatgaggtgctgcggaagggttccggaactctctgtgaagcc
ttgctgatggtgcaggctttccatgccaacatcgtcttccccaacaagcaagaacaggag
ttcaacaagctgacggatgacggccatgtgctggacgccgagacctacgtgggtggccac
gtggaggccctggaatcaggagtgttccgcagtgacatcccctgtcgcttcaggatgaac
cctgtggccttcgacttcctgctgcagcgggttgagaagaccctgcgccatgctgttgaa
gaagaggagaaggtgcccatcgagcaggtcaccaacttccaagaggtgtgcgatcagatt
aagagcagactcatctccctgaaggatgtccctaatcgaatcgagtgccccctgatctac
cacctggatgtgggagccatgtaccccaacatcatcctcaccaaccgcctgcagccctcc
gccatggtggacgaggccacctgtgccgcctgtgactttaacaagcctggagccaactgt
cagaggaagatggcttggcagtggaggggcgagttcatgccagccagccgcagcgagtac
caccgcatccagcaccagctggagtcggagaagttccctcccctgttcccagagggcccg
gcccgcgcctttcacgagctgtcccgggaggagcaggccaagtatgagaagcggaggctg
gcagactactgccgaaaagcatataagaagctccacgtgacccgggtggagcagcgcctc
accaccatctgccagcgggagaattctttctatgtggacacggtccgcgccttccgggac
cggcgttatgagttcaaggggctgcacaaggtgtggaagaagaaattgtccgcagccgtg
gaggcgggcgacgcagctgaagtgaagcgctgcaagaacatggagatcctgtacgactcc
ctgcagctggcccacaagtgcatcctcaactccttctacggctacgtcatgcgcaagggg
gcacgttggtactccatggagatggctggcatcgtctgcttcacgggggccaacatcatc
acgcaagcccgggagctcatcgagcagatcgggcggcccttagagctggacacagatggg
atatggtgcgtcctgcccaacagcttccctgaaaactttgtcgtcaagacaaccaatgtg
aagaagcccaaggtgaccatctcctacccaggggccatgctgaacatcatggtcaaggag
ggcttcaccaaccaccagtaccaggagctggctgagccctcctcactcacctacgtcacc
cgctctgagaacagcatcttctttgaagtcgatgggccttaccttgccatgatcctgccg
gcctccaaggaagaaggcaagaaactgaagaagagatacgctgtgttcaacgaggacggt
tccctggccgagctcaagggcttcgaggtcaagcggcggggggaactgcagctgatcaag
atcttccagtcctcggtgttcgaggctttcctcaaaggcagcacgctggaggaggtgtat
ggctccgtggccaaggtggccgactactggctggacgtgctatacagcaaggcggccaac
atgccagactcggaactgtttgagctcatctcagagaaccgctccatgtctcggaagctg
gaggactacggggagcagaagtcgacctccatcagcaccgccaaacgcctggctgagttc
ctgggcgaccagatggtcaaggatgcagggctgagctgccgatacatcatctcccgcaag
cccgagggctcacctgtcacggagagggccatcccactggccatcttccaggcagagcca
atggtgaggaagcactttctccggaagtggctcaagagctcgtccttgcaggagtttgat
atccggacgatcctggactgggactactacattgagcggctggggagcgccatccagaag
atcatcaccatccccgcagccctgcagcaggtgaaaaacccggtgcccagagtcagacac
cccgactggctgcataaaaagctgctggagaagaacgacgcctacaagcagaagaagatc
agcgagttgtttgtcgtcgagggcaagagacaggttgtgatgaaccaggctcccgagggt
agcccgagccccagggcccccgacatggaggacatcggccttgcaaagcccccacgcgta
gcagttcctgtggtcactaagaggaagcgggtcctcttggaggagagccaggaggagtct
caggagctgacggtgtcctggcaggaggtcttggggcagccccccccactgggcaccacc
caggaagagtttctggtgtggcttcgcttccacaagaagaagtggcagctgcaggcccgg
cagcgcctggcgcgcaggaagagacagcgtcacgagtgcacggaggacacactgcgggct
ggggtgcgccgagaggggcctgccatggggctggggagcttcctgcagcggaccgcccgc
agcatcctggacctcccctggcagatagtgcagatctgcgagaccagccagccgggcctg
ttcaggctgtgggccgtcattggcagcgacctgcactgcatcaagctgagcattcctcga
gtgttctacgtgaacaagcaggtggcaaaggcagaggaagggccctcttgtcgtaaggtg
aaccgggtgctgcctcgagccactgtggtccacaacttgtacgagtactcggtgcctgag
gacatgtaccaggagcacatcaacaagatcaacacagagctgtccgctcctgacgtcgag
ggcgtctacgagactcaggtgccgctgctgttccgggcccttgtgcagctcggctgcttg
tgtgtggtcaacaagcagttggtgaggcacctctctggcctggaagtaaacacctttgcc
ctggagcacctggagatgcgttctctggcccagttcagctacctggagccaggaagcatc
cgccacctctacctgtatcaccacctgcaaggccacaaggcgctctttggggtcttcttc
cccacgcagcgcagggcctctgtgtttgtgctggacacggtccgcagcaaccagatgccc
agccttggcaccatgtactcctcagcgcacgggctcctcctggagcagctgggccccgac
ttcctgcctccccccaagcatacctttgaggttcgagcagagacagacctgaagaccatc
tgcagagccatccagcgcctcctgctggcgtacaaagaggagcgccgggggcccactctg
atcgctgtgcagtccagctgggagctgaggcagttggtgggcgaggtcccggtgctggag
gagtttcccctggtgccggtgcgggtggccgagaaggtcagctacgcggtcctggactgg
cagcgccaaggggcacggcacatgatccgacattacctccacctggacacctgcctgtcc
caggcctttgagatgagcaggtatttccatattcctgtggggaacctgccagaggacatc
tccaccttcggctccgacctcttctttgctcgccacctccagcgccacagccacctcctg
tggctgtcccccacatcccggcctgacctgggcggcagggaggcagataacagccgcttg
gtcatggagctggacgaccgcaccatggtggagatcaacagctcgggctgctactccaca
gtgtgcgtcgagctggacctccagaacctcgctgtcaacaccgtgctgcagtcacaccgt
gtcaacgacatggagggggcggccagtgtgggcatcagctttgacgccatcccgcaggcc
tccctggaggacatgatcacgggcaaccagggggcctgcatgcctgccagctatgacgag
acggctctctgctccagcactttcagggtcctgaagagcatggtggtgggctgggtgaag
gaaatcacgcagtaccacaacgtctacgccgacaaccaggtgatgcacttctaccggtgg
ctgcggtccccgtcctccctgctccacgaccctgccctgcatcgcaccctgtacagcatg
atgaagaagctcttcctgcagctcatcgctgagttcaagcggctggggtcgtccatcgtc
tatgctaacttcaaccgcatcatcctctgcacgaagaagcgccgcatcgaggacgccctg
gcctacgtggagtacatcaccaacagcatccattccaaggagctcttccgctccctgacc
ctttccttctctcggtgctgggactttcttctctggatggacccgtctaactacggggga
gtcaaagggaaagtcccctcgagtgttcatcgtgggcagcagcgagcatctccaggaggg
gaggacgaggaggaggaggaggaggacgccgccgacgaggtggaagagagcttagaggaa
gccagagtggaggacttactagaaaacaagtggaacattttacagtacctgcctcaggcg
gcctcctgccaaagctacttcctcatgatcgtctcagcctacatcgtggctgtgtaccac
agcatgaaggaggagctgcggcgcagtgccccggggagcacccctgtgaagaggagaggg
gccagccagttctcccaggagacagaggccacggccgggtctctgcctggaatgatcacc
ttctctcaggactacgtggcaaatgagctcacccagaacttcttcaccatcacgcagaag
attcagaagaaagttacgggctcacggaactcgacggagccctcagagatgttcccgcag
ctcccaggttctcacctggtgctcaacaacccggccctggagttcaccaagtacgtgtgc
aaggtgctgtccctggacacgaacatcacgaaccaggtcaacaagctgcgccgggacctg
atgcgcctggtgggtgtcggggagttttcgccagaggcacagttccaagacccttgccgc
tcctacgtgctcccagaggtcatctgccacagctgcaacttctgccgggacctggacctg
tgcaaagactctgccttctcccaggacggggcgatcctccctcggtggctctgccccaac
tgtgaggagccctatgaccccacggtcatcgaggccgccctggtggaagcgctgcagaaa
aagctgatggccttcatgcagcaagacctggtctgcctgaagtgcggcgctgtgaaggac
acccacatgcccatccactgcagctgtgccggcgacttcgccctcaccatccacaccgcg
gccttcttagagcagatgggaatcttccggaacatcgcccagcactacggcatgtcttac
ctcctggagactttggagtgggcactgcggaagacccctcccccatgctgctag
DBGET
integrated database retrieval system
