Echinops telfairi (small Madagascar hedgehog): 101652848
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Entry
101652848 CDS
T08707
Symbol
EGFR
Name
(RefSeq) epidermal growth factor receptor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01521
EGFR tyrosine kinase inhibitor resistance
etf01522
Endocrine resistance
etf03272
Virion - Hepatitis viruses
etf04010
MAPK signaling pathway
etf04012
ErbB signaling pathway
etf04014
Ras signaling pathway
etf04015
Rap1 signaling pathway
etf04020
Calcium signaling pathway
etf04066
HIF-1 signaling pathway
etf04068
FoxO signaling pathway
etf04072
Phospholipase D signaling pathway
etf04144
Endocytosis
etf04151
PI3K-Akt signaling pathway
etf04510
Focal adhesion
etf04520
Adherens junction
etf04540
Gap junction
etf04630
JAK-STAT signaling pathway
etf04810
Regulation of actin cytoskeleton
etf04912
GnRH signaling pathway
etf04915
Estrogen signaling pathway
etf04921
Oxytocin signaling pathway
etf04926
Relaxin signaling pathway
etf04928
Parathyroid hormone synthesis, secretion and action
etf04934
Cushing syndrome
etf05160
Hepatitis C
etf05163
Human cytomegalovirus infection
etf05165
Human papillomavirus infection
etf05171
Coronavirus disease - COVID-19
etf05200
Pathways in cancer
etf05205
Proteoglycans in cancer
etf05206
MicroRNAs in cancer
etf05207
Chemical carcinogenesis - receptor activation
etf05208
Chemical carcinogenesis - reactive oxygen species
etf05210
Colorectal cancer
etf05212
Pancreatic cancer
etf05213
Endometrial cancer
etf05214
Glioma
etf05215
Prostate cancer
etf05218
Melanoma
etf05219
Bladder cancer
etf05223
Non-small cell lung cancer
etf05224
Breast cancer
etf05225
Hepatocellular carcinoma
etf05226
Gastric cancer
etf05230
Central carbon metabolism in cancer
etf05231
Choline metabolism in cancer
etf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
101652848 (EGFR)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101652848 (EGFR)
04012 ErbB signaling pathway
101652848 (EGFR)
04014 Ras signaling pathway
101652848 (EGFR)
04015 Rap1 signaling pathway
101652848 (EGFR)
04630 JAK-STAT signaling pathway
101652848 (EGFR)
04066 HIF-1 signaling pathway
101652848 (EGFR)
04068 FoxO signaling pathway
101652848 (EGFR)
04020 Calcium signaling pathway
101652848 (EGFR)
04072 Phospholipase D signaling pathway
101652848 (EGFR)
04151 PI3K-Akt signaling pathway
101652848 (EGFR)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101652848 (EGFR)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101652848 (EGFR)
04520 Adherens junction
101652848 (EGFR)
04540 Gap junction
101652848 (EGFR)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101652848 (EGFR)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
101652848 (EGFR)
04915 Estrogen signaling pathway
101652848 (EGFR)
04921 Oxytocin signaling pathway
101652848 (EGFR)
04926 Relaxin signaling pathway
101652848 (EGFR)
04928 Parathyroid hormone synthesis, secretion and action
101652848 (EGFR)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101652848 (EGFR)
05206 MicroRNAs in cancer
101652848 (EGFR)
05205 Proteoglycans in cancer
101652848 (EGFR)
05207 Chemical carcinogenesis - receptor activation
101652848 (EGFR)
05208 Chemical carcinogenesis - reactive oxygen species
101652848 (EGFR)
05230 Central carbon metabolism in cancer
101652848 (EGFR)
05231 Choline metabolism in cancer
101652848 (EGFR)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101652848 (EGFR)
09162 Cancer: specific types
05210 Colorectal cancer
101652848 (EGFR)
05212 Pancreatic cancer
101652848 (EGFR)
05225 Hepatocellular carcinoma
101652848 (EGFR)
05226 Gastric cancer
101652848 (EGFR)
05214 Glioma
101652848 (EGFR)
05218 Melanoma
101652848 (EGFR)
05219 Bladder cancer
101652848 (EGFR)
05215 Prostate cancer
101652848 (EGFR)
05213 Endometrial cancer
101652848 (EGFR)
05224 Breast cancer
101652848 (EGFR)
05223 Non-small cell lung cancer
101652848 (EGFR)
09172 Infectious disease: viral
05160 Hepatitis C
101652848 (EGFR)
05171 Coronavirus disease - COVID-19
101652848 (EGFR)
05163 Human cytomegalovirus infection
101652848 (EGFR)
05165 Human papillomavirus infection
101652848 (EGFR)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101652848 (EGFR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101652848 (EGFR)
01522 Endocrine resistance
101652848 (EGFR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101652848 (EGFR)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
etf04147
]
101652848 (EGFR)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101652848 (EGFR)
Protein kinases [BR:
etf01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
101652848 (EGFR)
Exosome [BR:
etf04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
101652848 (EGFR)
Exosomal proteins of pancreatic cancer cells
101652848 (EGFR)
Exosomal proteins of bladder cancer cells
101652848 (EGFR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
GF_recep_IV
Recep_L_domain
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
101652848
NCBI-ProteinID:
XP_012861453
LinkDB
All DBs
Position
Unknown
AA seq
1123 aa
AA seq
DB search
MFNNCEVVLGNLEITYVQRNYDLTFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNLLY
ENTYALAVLSNYATNKTGMRELPMRNLQEILNGAVRFSNNPVLCHVGTVQWRDIVDSHFM
SNMSMDLQNSLDNCQKCDPNCPNGSCWGAGEENCQKLTKTICAQQCSGRCRGKSPSDCCH
NQCAAGCTGPRESDCLICRRFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVK
KCPHNYVVTDHGSCVRFCSADSYEVDEDGVHKCKKCEGLCPKVCNGIGIGEFKDTLSINA
TNIKHFKNCTTISGDLHILPVAFKGDSYTRTPPLDPKELDILKTVKEITGSGQFSLAVVG
LDITSLGLRSLKEISDGDVIISGNQKLCYANTINWKKLFGTTSQNTKIIKNKNKNVCEAM
GHVCDPLCSSEGCWGPGPKDCVTCRNVSRGRECVSKCNILEGEPREFVEKSECIECHPEC
LPQLMNITCTGRGPDNCIKCAHYIDGPHCVKTCPAGILGENNTLVWKYADANHVCHLCHT
NCTFGCAGPGLEGCPTNERKIPSIATGIVGGLLLLVVIALGIGLFLRRRRIIRKRTLRRL
LQERELVEPLTPSGEAPNQALLRILKETEFKKTKVLGSGAFGTVYKGLWIPEGEKVKIPV
AIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYI
REHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL
GAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASE
ISSILEKGERLPQPPICTIDVYMIMVKCWMIDAESRPKFRELINEFSKMARDPQRYLVIQ
GDERMHLPSPTDSNFYRGLMDEEDMEDVVDADEYLIPQQGFFNSPSTSRTPLLNSLSTTS
NNSTVACIDRNGQSCPVKEDSFLQRYSSDPTGALTEANIDDDFLPAPEYINQSIPKRPAG
SVQNPVYHNQPLNPAPGRDPHYQNPHSNAVQNPEYLNTIPPACVNSPAFWAQKGNHQVSL
DNPDYQQDFFPKETKPNGILKGPAAENAEYLRVAPPSSEFIGA
NT seq
3372 nt
NT seq
+upstream
nt +downstream
nt
atgttcaataactgcgaagtggtccttgggaatttggaaattacctatgtgcaaaggaat
tatgaccttaccttcttaaagaccatccaggaggtggctggctacgtactcattgccctc
aacacggtggagaggattcccttggaaaatctgcagatcattagaggaaatttactttat
gaaaacacctatgctttggcagtcttatccaactatgccacaaataaaaccggcatgagg
gagctgcccatgaggaatttacaagagattctgaacggtgctgtgagattcagcaataac
cccgtcctctgccacgtggggaccgtccagtggcgagacattgtggacagtcattttatg
agcaacatgtcgatggacctccagaacagtctggacaactgccaaaagtgtgatccaaac
tgtcccaatggaagttgctggggtgcaggagaggagaactgccagaaattgaccaaaacc
atctgtgcccagcagtgttcgggacgctgtcgaggcaagtcccccagtgattgctgccac
aaccagtgtgccgccggctgcacgggtccccgggagagcgactgcctgatctgccgcagg
tttcgagacgaagccacatgcaaggacacctgtccgccattaatgctctacaaccccacc
acctaccagatggacgttaatccagaggggaaatacagctttggcgccacttgtgtgaaa
aagtgcccacataactatgtggtgacagaccacgggtcctgtgtccgtttctgcagtgct
gacagctacgaggtggacgaggatggcgtgcacaagtgtaaaaagtgtgaggggctgtgt
cctaaagtgtgtaatggaattggaattggtgagtttaaagacacgctttccataaatgct
acaaatattaagcacttcaaaaattgcacgactatcagtggagatcttcatattctgcca
gtagcatttaagggtgactcctacacacgcacgccacctctagatccgaaggaactggac
attctaaaaactgtcaaggaaataacaggttctggccagttttcacttgcggttgtcggc
ctggacataacatccttgggattacgctctctcaaggaaataagtgatggagacgtgatc
atttccggaaaccagaaactgtgctatgccaatacaataaactggaaaaaactatttggg
actacaagtcagaacactaagattataaaaaacaaaaacaaaaatgtctgtgaggccatg
ggccacgtttgtgatcccttgtgctcatcagagggttgctggggcccagggcccaaagac
tgtgtcacctgccgcaatgttagccgaggccgggaatgtgtgagcaagtgcaacattctg
gagggagagccaagggagtttgtggagaagtctgagtgcatcgagtgccatcctgaatgt
ctgccgcagctcatgaacataacctgcacgggacgcgggcctgacaactgcataaagtgt
gcccactacatcgatgggccccattgtgtcaagacctgcccagcaggaatcctgggagaa
aacaatacgttggtctggaagtatgcagatgccaatcacgtgtgtcacctgtgccacaca
aactgcactttcggctgtgctgggccaggtctcgaaggctgtccaacaaatgagcgcaag
atcccatccatcgccactggaattgtgggtggcctcctcttactggtggtgattgccctc
ggtattggcctcttcctgcgcaggcgccgcatcatccggaagcgcacgctgcgccgactg
ctgcaggaaagagagcttgtggagcctctgacccccagtggagaagcgcccaaccaagct
cttctgaggatcttaaaggaaactgaattcaagaagaccaaagtgctgggctctggagca
ttcggcaccgtgtataagggactctggatcccagaaggagagaaagttaaaattcctgta
gctatcaaggaattaagagaggcgacgtctcccaaagccaacaaggaaattcttgatgaa
gcctatgtcatggccagtgtggacaatccccatgtgtgccgcctgctaggcatctgcctg
acctccacagtccagctcatcacgcagctcatgcccttcggctgcctcctggactacatc
cgtgagcacaaggacaacatcggctcccagtatctcctcaactggtgtgtccagatcgca
aagggcatgaactacctggaagaccgccgcctggtgcaccgtgaccttgcggcgaggaac
gtcctggtgaagacgccgcagcacgtcaagatcacggattttgggctggccaagctgctc
ggtgccgaggagaaggagtaccatgccgagggaggcaaagttcctattaaatggatggct
ctggaatcaattttacaccgaatttatacccaccaaagtgatgtctggagctacggtgtg
acagtttgggagttgatgaccttcggatccaagccctatgatggaatccctgccagtgag
atctcgtccatcctggaaaaaggagagcgccttccacagccacccatctgcaccattgat
gtctacatgatcatggttaaatgctggatgatagatgcagaaagtcgcccaaagttccgg
gagttgatcaatgaattctccaaaatggcccgtgaccctcagcgctaccttgtcattcag
ggcgatgagcgaatgcatctgccaagccccacagactcaaacttttaccgcggcctgatg
gacgaagaggacatggaagatgtcgtggacgcggacgagtacctcattccacagcaaggc
ttcttcaacagcccttccacttctcgaaccccccttctcaattctctgagcacaaccagc
aataattccactgtggcctgcatcgacagaaacgggcagagctgccctgtcaaggaggac
agcttcttacagcggtacagctccgatcccacgggcgctttgaccgaagcgaacatcgat
gacgatttcctcccagcgccagagtacataaaccaatccattcccaaaaggcctgcaggt
tctgtgcagaaccctgtctaccacaatcagcctctgaatcctgcccctggccgagaccct
cactaccaaaacccccacagcaacgccgtgcagaatcccgagtatctcaacaccatcccg
cctgcctgtgtcaacagccctgccttctgggcccagaaaggcaaccatcaagtcagtctg
gacaacccggactaccaacaggacttctttcccaaggaaaccaagcccaatggcatcctt
aagggtccggcagctgaaaatgcagaatacctaagggtcgcaccaccgagcagtgagttt
attggagcatga
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