Echinops telfairi (small Madagascar hedgehog): 101655021
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Entry
101655021 CDS
T08707
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00230
Purine metabolism
etf00670
One carbon pool by folate
etf01100
Metabolic pathways
etf01523
Antifolate resistance
Module
etf_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101655021 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101655021 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101655021 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
etf04147
]
101655021 (ATIC)
Enzymes [BR:
etf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
101655021 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
101655021 (ATIC)
Exosome [BR:
etf04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
101655021 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
DUF5938
Motif
Other DBs
NCBI-GeneID:
101655021
NCBI-ProteinID:
XP_004701648
UniProt:
A0ABM0IJW1
LinkDB
All DBs
Position
Unknown
AA seq
546 aa
AA seq
DB search
VFRDVSELTGFPEMLGGRVKTLHPAVHAGILARDIPEDNEDMARLDFNLIRVVVCNLYPF
VKTVASPDVSVEAAVEQIDIGGVTLLRAAAKNHARVTVVCDPGDYEAVSGEMQSSDRKDT
SLETRCQLALKAFTHTAQYDEAISDYFRRQFSKGVSQLPLRYGMNPHQTPAQLYTLQPRL
PLTVVNGAPGFINLCDALNAWQLVKELKEALGLPAAASFKHVSPAGAAVGFPLSEDEAKV
CMVFDLYPTLTPIATAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIVAPGY
EEAALKILSKKKNGNYCVLQMDPSYKPDENEVRTLFGLRLSQKRNNGVIDGSLFSNIVTK
KKELPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANCWW
LRHHPRVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLRKWEALFEEVPAPLTEAEKQQ
WVDTLGEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADQVVTEACNELGIILAHTS
LRLFHH
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
gttttcagagacgtctcggagctgacagggtttccggaaatgttagggggccgggtgaaa
accctgcatcccgcagtccacgcaggaatcttggctcgtgatatcccagaagataatgag
gacatggccagacttgatttcaatctcataagagttgtggtctgcaatctctatccgttc
gtgaaaacggtggcttctccagacgtctctgtggaggcagctgtggagcaaatcgacatt
ggtggcgtcaccttactgagagcagcagccaaaaaccacgcgcgcgtgaccgtcgtgtgt
gacccaggggactacgaggcggtgtccggggagatgcagagctctgaccgtaaagacacc
tccttggagactaggtgccagctagccttgaaggcgttcactcacactgcccagtacgat
gaggcaatttccgattacttcaggaggcagttcagtaaaggagtgtcccagctgcccttg
aggtacgggatgaacccgcatcaaacacctgctcagttgtacacactgcagcccagactt
cccctcacagttgtaaatggagcccctggatttataaacctgtgtgatgcgttgaacgcc
tggcagctggtaaaggagctcaaagaagctttgggcctccccgccgctgcctctttcaaa
cacgtcagtccagcaggtgctgctgttgggtttccactcagtgaagatgaggccaaagtg
tgcatggtcttcgatctctaccccaccctcacgcccattgctaccgcgtatgccagagca
agaggggctgataggatgtcttcatttggtgattttattgcactgtctgatatttgtgat
gtccctactgccaaaatcatctccagagaggtgtctgatggcattgttgcgccaggatat
gaagaagcagccctgaaaattctgtctaaaaagaaaaatggaaactactgtgtgcttcag
atggacccttcgtataaaccagatgaaaatgaagttcgaactctctttggtctgcgttta
agccagaagagaaataacggtgtcatcgacgggtcattatttagcaatattgttaccaag
aagaaagagttgccggagtctgcactcagggacctcatcgtcgccaccattgcagtcaag
tacactcagtctaattccgtgtgctacgccaagaacgggcaggtcatcggcattggagct
gggcagcagtctcgaattcactgcacgcgccttgcaggggataaggcaaactgttggtgg
cttagacaccacccgcgagtgctttcgatgaagtttaaaaccggagtgaagagggcagaa
atctctaatgccatcgatcaatatgttactggaaccattggcgaggatgaagatctgaga
aagtgggaggcgctgtttgaggaagtccccgcaccattgaccgaggccgagaagcagcag
tgggtggacacacttggtgaagtttctatcagttcggatgccttctttcctttcagggat
aatgtagaccgagctaaaaggagtggggtggcctacattgccgctccgtccggttctgcc
gctgaccaagttgtgactgaggcctgcaacgaactggggatcatcctggctcataccagt
ctccgtctctttcatcactga
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