Echinops telfairi (small Madagascar hedgehog): 101655735
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Entry
101655735 CDS
T08707
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf00760
Nicotinate and nicotinamide metabolism
etf01100
Metabolic pathways
etf04068
FoxO signaling pathway
etf04148
Efferocytosis
etf04152
AMPK signaling pathway
etf04211
Longevity regulating pathway
etf04213
Longevity regulating pathway - multiple species
etf04218
Cellular senescence
etf04310
Wnt signaling pathway
etf04922
Glucagon signaling pathway
etf04936
Alcoholic liver disease
etf05031
Amphetamine addiction
etf05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
101655735 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101655735 (SIRT1)
04068 FoxO signaling pathway
101655735 (SIRT1)
04152 AMPK signaling pathway
101655735 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101655735 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
101655735 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101655735 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
101655735 (SIRT1)
04213 Longevity regulating pathway - multiple species
101655735 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101655735 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
101655735 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101655735 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
etf03036
]
101655735 (SIRT1)
03029 Mitochondrial biogenesis [BR:
etf03029
]
101655735 (SIRT1)
Enzymes [BR:
etf01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
101655735 (SIRT1)
Chromosome and associated proteins [BR:
etf03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
101655735 (SIRT1)
Mitochondrial biogenesis [BR:
etf03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
101655735 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
101655735
NCBI-ProteinID:
XP_004701181
LinkDB
All DBs
Position
Unknown
AA seq
626 aa
AA seq
DB search
MGKCSGARRSPGLGRAAGAKLKDNLLFSDEIITNGFHSCESDEDDRASHASSSDWTPRPR
IGPYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDIN
TIEDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEY
FRKDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQ
CHGSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQ
FHRAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHDVPQILINREPLPHLHFDVELLGD
CDVIINELCHRLGGEYAKLCCNPVKLSEVTEKPPRTQRELVQLSELPPTPLNISEDSSSP
ERTSPPDSSVIVTLLDPTKSNTDSNVSESKEYMEEKSQEVQLSTRNIESMTEQLENADLK
NVGSNIGEKNERTSVAETVRKCWPIRLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDS
EDDVLSSSSCGSNSDSGTCHSPSLEEPLEDESEIEEFYNGLEDDVDVSERPGGPGFGTDG
SDQEAINEALSVKQEAADINYSSTKS
NT seq
1881 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagtgctcgggagcgcgccggagcccagggctggggagggcggcgggagcgaag
ttgaaagataatcttctgttcagtgatgaaattatcactaatggcttccattcctgtgaa
agtgatgaggatgatagagcctcacatgcaagctctagtgactggactcccaggccacgg
ataggtccatatacttttgttcaacaacacctcatgattggaacagaccctcgaacaatt
ctaaaagatttactaccagaaacaatccctccaccagaattggatgatatgacgctgtgg
cagattgttatcaatatcctttcagaaccaccaaaaagaaaaaaaaggaaagatattaat
acaattgaagatgctgtgaaattactgcaggagtgcaaaaaaatcatagttttaactgga
gctggggtatctgtctcctgtggaatacctgacttccggtcaagagatggcatttatgcc
cgccttgcagtggacttcccagaccttcccgaccctcaagcaatgtttgatattgaatat
ttcagaaaggatccaagaccattcttcaagtttgcaaaggaaatatatcccggacagttc
cagccatctctctgtcacaaatttatagctttgtcagataaagaaggaaaactacttcgc
aactatactcagaacatagacacactggagcaggttgcaggaattcaaaggataattcag
tgtcatggatcctttgcaacagcatcttgcctgatttgtaaatataaagttgactgtgaa
gctgtacgaggggatatttttaatcaggtggttcctcgatgtcctaggtgcccagctgat
gaaccacttgctatcatgaaaccagagattgtcttttttggtgagaatttaccagaacag
tttcatagagccatgaagtatgacaaagatgaagttgatctcctcattgttattgggtct
tccctgaaagtaagaccagtagcactgattccaagttccataccccatgatgtgcctcag
atattaattaatagggaacctttgccgcatttgcattttgatgtagagcttcttggagac
tgtgatgtcataattaatgaattgtgtcataggctaggtggtgaatatgccaaactttgt
tgcaacccggtaaaactttctgaagttactgaaaaacctccacgaacacaaagggagttg
gttcagttgtcagaattgccacccacacctcttaatatttcagaagactcaagttcacca
gaaagaacttcaccaccagattcttcagtgattgtcacacttttagacccaactaagagt
aatactgattcaaatgtgtcagaatcaaaagaatatatggaagaaaaatcacaggaagta
cagctttctactaggaacattgaaagtatgaccgaacagttggagaatgcagatttgaag
aatgttggttccaatattggagagaaaaacgaaagaacttcagttgctgaaacagtgagg
aagtgctggcccattcgacttgcaaaggagcagattagtaagcgtcttgatggtaatcag
tatctgtttttaccaccaaatcgttatattttccatggcgcagaggtatattcagattct
gaagatgatgtcctatcctctagttcttgcggcagtaacagtgatagtggaacgtgccac
agcccaagtttagaagagcccttggaggatgaaagtgagattgaagaattctacaatgga
ttggaagatgatgttgatgtttcagaaagacccggaggacctggatttgggactgatgga
agtgatcaagaggccattaatgaagctttatctgtgaaacaggaagcagcggacattaac
tattcatcaaccaaatcataa
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