Echinops telfairi (small Madagascar hedgehog): 101659376
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Entry
101659376 CDS
T08707
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01521
EGFR tyrosine kinase inhibitor resistance
etf04062
Chemokine signaling pathway
etf04148
Efferocytosis
etf04151
PI3K-Akt signaling pathway
etf04217
Necroptosis
etf04550
Signaling pathways regulating pluripotency of stem cells
etf04630
JAK-STAT signaling pathway
etf04658
Th1 and Th2 cell differentiation
etf04659
Th17 cell differentiation
etf04725
Cholinergic synapse
etf04917
Prolactin signaling pathway
etf04920
Adipocytokine signaling pathway
etf04933
AGE-RAGE signaling pathway in diabetic complications
etf04935
Growth hormone synthesis, secretion and action
etf05140
Leishmaniasis
etf05145
Toxoplasmosis
etf05152
Tuberculosis
etf05161
Hepatitis B
etf05164
Influenza A
etf05167
Kaposi sarcoma-associated herpesvirus infection
etf05168
Herpes simplex virus 1 infection
etf05200
Pathways in cancer
etf05207
Chemical carcinogenesis - receptor activation
etf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
etf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101659376 (JAK2)
04151 PI3K-Akt signaling pathway
101659376 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101659376 (JAK2)
09143 Cell growth and death
04217 Necroptosis
101659376 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101659376 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
101659376 (JAK2)
04659 Th17 cell differentiation
101659376 (JAK2)
04062 Chemokine signaling pathway
101659376 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101659376 (JAK2)
04917 Prolactin signaling pathway
101659376 (JAK2)
04935 Growth hormone synthesis, secretion and action
101659376 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
101659376 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101659376 (JAK2)
05207 Chemical carcinogenesis - receptor activation
101659376 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101659376 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
101659376 (JAK2)
05164 Influenza A
101659376 (JAK2)
05168 Herpes simplex virus 1 infection
101659376 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101659376 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
101659376 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101659376 (JAK2)
05140 Leishmaniasis
101659376 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101659376 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101659376 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101659376 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101659376 (JAK2)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101659376 (JAK2)
Protein kinases [BR:
etf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101659376 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
FERM_C_FAK1
Kdo
ABC1
Kinase-like
RIO1
FERM_M
Motif
Other DBs
NCBI-GeneID:
101659376
NCBI-ProteinID:
XP_004714516
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MGMACLTMADMEGPSASPVHQNGDIPGSTHPLKQVEPVLQVYLYHSLGKAEEDYLSFPVG
EYVAEEICVAASKACGITPVYHNMFALMSEAERVWYPPNHVFHIDESTRHIVLYRIRFYF
PHWYCHGSNRTYRHGIARGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLAVYNSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIQQF
SQCKATARNLKLKYLINLETLQSAFYTEQFEVKEHGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQMYCDFPDIIDVSIKQANQEGSNESRVVTIHKQDTKNMEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GMYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNDNGEYNLSGTKKNFNNLKDLLNC
YQMETVRSDSIIFQFSKCCPPKPKDRSNLLVFRTNSVADVPTSPTLQRHNNVNQMVFHKI
RNEDLVFNESLGQGTFTKIFKGIRREVGDYGQRHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKYGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKGLIHGNVCAKNILLIREEDRRTGNPPFIKLSDPGISITVLPKDILQERIPWAP
PECIENPRNLSLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINHCMDYGPDFRPSFRAIIRDLNSLFTPDYELLMENDVLPNMRIGALGFSGVFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLLYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESRFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGTDKQGQMIVFHLIE
LLKNNGRLPRPEGCPDEIYMIMTECWNNNVIQRPSFRDLAVRVDRIRDSMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcctgcctcacaatggcagacatggaaggaccatccgcatctccggtgcat
cagaacggtgatattcctggatcgacacatcccctgaaacaggtggaacctgtcctccag
gtgtatctttaccactcactggggaaagctgaagaagactacctgagcttcccagtgggg
gagtatgtggctgaagagatttgtgttgctgcttctaaagcttgtggtatcactcctgtg
tatcataatatgttcgctttaatgagtgaagcggaaagggtctggtatccgcccaaccat
gtcttccatattgatgagtcaacgaggcacattgtactctacagaataaggttttacttt
cctcattggtactgtcatggcagcaacagaacctaccggcatgggatagctcgaggtgcc
gaagcgccccttctggatgacttcgtcatgtcttacctgtttgctcagtggcggcatgat
tttgtgcacggatggataaaagtcccagtgactcatgaaacacaggaagaatgtcttggg
atggcagtgctagatatgatgagaattgctaaagaaaaagatcagacccctctggctgtc
tataactcgatcagctacaagacattcttaccaaaatgtgttcgagctaagatccaagaa
tatcacattttgacacggaagagaataaggtataggtttcgcagatttattcagcagttc
agccaatgcaaagccactgccagaaacttgaaacttaaatatcttatcaatctggaaact
cttcagtctgccttctacacagaacagtttgaagtgaaagaacatggaagagggccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagatgtattgtgatttt
cctgatattattgatgtcagcattaagcaagcaaaccaagaaggctctaatgaaagcagg
gttgtaactatccataagcaagatactaaaaatatggaaattgaactgagctcattaaga
gaagctttgtcttttgtgtcactgattgatggatactatcgattgactgctgatgcacat
cattacctctgcaaagaggtcgcacctccaacagtgctggaaaacatacaaagcaactgc
catggcccaatctcaatggattttgccatcagtaaattgaagaaagctggtaatcagacg
ggaatgtacgtccttcgatgcagtcctaaggactttaataaatactttctcacctttgct
gttgagcgagaaaatgtcattgaatataagcactgtttgattacaaaaaacgataatgga
gaatacaacctcagtgggactaagaagaacttcaataatcttaaagatctcttgaattgc
taccagatggaaactgttcgttcggacagtataattttccagttttctaagtgctgtccc
ccaaagccaaaagatagatcaaaccttttagtcttcagaactaacagtgttgctgatgta
ccgacctcaccaacattacagaggcataacaatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttggtatttaatgaaagtcttgggcaaggcacttttacaaaaattttt
aaaggtataagaagagaagtaggagactatggtcaaaggcatgaaacggaggttcttcta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcacctggttttaaactacggagtgtgtgtgtgtggcgag
gagaatattctagttcaagagtttgtaaaatatgggtctctggacacatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaggtggctaaacagttggcctgggcc
atgcattttctagaagaaaaaggccttattcatgggaatgtgtgtgccaaaaatatccta
ctcatcagagaagaagacaggaggaccggaaatccccctttcatcaaactcagcgatcct
ggcattagtattacagtgttgccaaaggacattctccaggagagaataccatgggcaccg
cctgaatgcatcgaaaaccctaggaatctaagcttggccacagataaatggagttttggt
accacgctgtgggaaatttgcagcggaggagataaacctctaagtgctctggattcccag
aggaagctccagttctatgaagacagacaccagctccctgcacccaagtggacagagttg
gccaatcttataaatcactgtatggactatggacccgattttaggccttctttcagagcc
atcatacgagaccttaacagcttgtttacaccagattatgaactcttaatggaaaatgat
gtgctaccaaatatgaggataggtgccctgggattttctggtgtttttgaagacagggac
cctacacagtttgaagaaagacacttgaaatttttacagcaacttggcaagggtaacttt
gggagtgtggagatgtgccgctacgaccctctgcaggacaacactggggaagtggtggcc
gtgaagaagctccagcacagcactgaggagcacctgcgagacttcgagagggagatagag
atcctgaaatccctgcagcacgacaacatagtcaagtacaagggcgtgtgctacagtgct
ggtcggcgtaatctgagattaattatggagtatttaccatatggaagtttgcgagactat
ctccagaaacataaagagcgtatagatcataaaaaacttctgctgtacacgtctcagata
tgcaagggcatggaatatcttggcacaaaaaggtatatccacagggatctggcaacaaga
aatatattggtggagaatgagaacagagttaaaattggagattttgggttgaccaaagtt
ttgccccaagacaaagaatattacaaagtgaaggaacccggtgaaagccccatattctgg
tatgccccagaatctctgactgagagcagattttccgtggcctcagatgtgtggagcttt
ggagtggtgctgtatgagcttttcacctacattgagaagagcaaaagcccacctgcggaa
tttatgcgcatgattggcaccgacaagcaaggccagatgattgtgttccacttgatagag
ctcttgaagaacaatgggagactaccaaggccagagggctgtccagacgagatttacatg
atcatgacagaatgctggaacaacaacgtgattcagcgcccttccttcagggacctagct
gtgcgagtggatcggatccgggacagcatggcaggatga
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integrated database retrieval system
