Echinops telfairi (small Madagascar hedgehog): 101660158
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Entry
101660158 CDS
T08707
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04140
Autophagy - animal
etf04141
Protein processing in endoplasmic reticulum
etf04210
Apoptosis
etf04932
Non-alcoholic fatty liver disease
etf05010
Alzheimer disease
etf05012
Parkinson disease
etf05014
Amyotrophic lateral sclerosis
etf05016
Huntington disease
etf05017
Spinocerebellar ataxia
etf05022
Pathways of neurodegeneration - multiple diseases
etf05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101660158 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101660158 (ERN1)
09143 Cell growth and death
04210 Apoptosis
101660158 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101660158 (ERN1)
05012 Parkinson disease
101660158 (ERN1)
05014 Amyotrophic lateral sclerosis
101660158 (ERN1)
05016 Huntington disease
101660158 (ERN1)
05017 Spinocerebellar ataxia
101660158 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
101660158 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101660158 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101660158 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101660158 (ERN1)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101660158 (ERN1)
Protein kinases [BR:
etf01001
]
Serine/threonine kinases: Other
IRE family
101660158 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ
PQQ_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
101660158
NCBI-ProteinID:
XP_004707334
LinkDB
All DBs
Position
Unknown
AA seq
986 aa
AA seq
DB search
MALLAIALYYVLPSDWSLGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVVDLLTGEKQQTLSSTFAESLCPSTSLLYLGRTEYTITMYDTRSRELRWNATYFDY
AASLPEDDLDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVSLYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLMPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSALPLLEGPQTDGVTIGDKGECVITPSTDLKFDTALKGKNKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPRHRENVIPADAEKKSFEEVIHLVDQAAESSPTTVTQDV
EEKFAPAKPEAPVDSVLKDMATIILSTFLLIGWVAFIITYPMSMHQQQQLQHQQFQKELQ
KIQLLQQQQLPFHPASDSALDSEPLDTSGLYSESSATSSPSTSPRASNHSLHSSGSTSKV
GACPFPDQDDEDEETSMVLVGKISFCPKDVLGHGAEGTIVYRGMFDSRDVAVKRILPECF
SFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDLAHLGLEPI
TLLQQTTSGLAHLHSLSIVHRDLKPHNILLSMPNAHGRVKAMISDFGLCKKLAVGRHSFS
RRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANIL
LGAYSLDCLHLEKHEDIVARELIEKMIAMDPQTRPSAKQVLKHPFFWGLEKQLQFFQDVS
DRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRN
KKHHYRELPAEVRETLGSIPEDFVRYFTARFPHLLSHTYRAMGLCRHERLFQPYYCQQPP
DPQPPCLPAAPPESGQMPLYAQPQLD
NT seq
2961 nt
NT seq
+upstream
nt +downstream
nt
atggcccttctagccatcgccctgtactacgttctacccagtgactggagtctcggaagc
cccagcacagtgacgcttccagaaacgttgctgtttgtgtcaaccctggacggcagcttg
cacgccgtgagcaagaggaccggctccatcaaatggactttaaaggaagacccagtcctc
caggttccaacacacgtggaagagcctgcgttcctcccagatcccaatgatggtagcctc
tatacccttgggggcaagaacaatgaaggcctcacgaaacttccctttaccatcccagag
ttggtgcaggcctccccgtgccgaagctcagatggaattctctacatgggtaaaaagcag
gacatttggtacgttgtcgaccttctgaccggggagaagcagcagacgctgtcgtcgacc
ttcgcagaaagtctgtgcccgtccacctcgcttctgtacctcgggcggacagagtacacc
atcaccatgtacgacaccagatcccgggagctccgctggaacgcaacctactttgactac
gccgcctcactgcccgaggacgacctggactacaagatgtcccacttcgtgtccaatggc
gacgggctggtggtgaccgtggacagtgaatccggggacgtcctttggatccaaaactac
gcctcccctgtggtgtccctttacgtctggcagcgggagggcctgcggaaggtgatgcac
atcaacgtcgccgtggagaccctgcgctacctgaccttcatgtccggggaggtggggcgc
atcaccaagtggaagtaccccttccccaaggagacggaggccaagagcaaactcatgccc
accctgtatgttgggaaatactctaccagcctgtatgcctccccctccatggtgcatgaa
ggggtcgcagtcgtgccccgcggcagcgctcttcccttgctggaaggcccccagaccgac
ggggtcaccattggcgacaagggcgagtgcgtgatcacgcccagcacggacctgaagttt
gacactgctctcaaagggaagaacaagctcaactacctgaggaactactggcttctgata
ggccaccacgaaacgccgctgtccgcctcaaccaagatgctggagaggttccccaacaac
ctgccccggcatcgggagaacgtgattcctgccgacgccgagaagaagagcttcgaggag
gtcatccacctggtagaccaggcggccgagagctcgcccaccaccgtcacccaggatgtg
gaagagaagttcgcccccgccaagcccgaggcccctgtggactctgtgctcaaggacatg
gccaccatcatcctgagtaccttcctgctcattggctgggtggccttcatcatcacctac
cccatgagcatgcaccagcagcagcagctgcagcaccagcagttccagaaggaactgcag
aaaatccagctcctgcagcagcagcagctgcccttccacccagcctccgactcggcgctg
gactcggagcccctggacacctctggcctctattcggagagctcggccaccagcagcccc
agcacgtcccccagagcctccaaccactccctgcactccagcggctccacctccaaggtc
ggagcctgccccttcccggaccaggatgatgaggacgaggagaccagcatggtgttagtt
gggaaaatttcattttgtcccaaggacgtcttgggccacggagcagagggcacaattgtg
tacagaggcatgttcgacagccgagacgtggccgtgaagcggatcctccccgagtgtttc
agcttcgcggaccgcgaggtgcagctgctgcgggagtcagacgagcaccccaacgtgatc
cgttacttctgcacggagcgggaccggcagttccagtacatcgctatcgagctgtgcgca
gccacgctgcaggagtacgtggaacagaaggacttggcccaccttggcctggagcccatc
accttgctgcagcagaccacctcgggcctggctcacctccactccctcagcatcgttcac
agagacctgaagccccacaacatcctcctgtccatgcccaacgcacacggcagggtcaag
gccatgatctccgacttcggcctctgcaagaagctagcagtcggcaggcacagcttcagc
cgccgatccggggtgcccggcacagagggctggatcgcccccgagatgctgagcgaggac
tgcaaggagaaccctacttacacggtggacatcttctctgcgggctgtgtcttttactac
gtcatctctgagggcagccaccccttcggcaagtccctgcagcgacaagccaacatcctc
ctgggagcctacagcctggactgcttacacctggagaagcatgaggacatcgtcgcgcgt
gagctaatagagaagatgatcgcgatggacccccagacgcgcccctcggcgaagcaggtg
ctcaagcaccccttcttctggggcctggagaagcagctgcagttcttccaggacgtgagc
gaccggatcgagaaggaggccctggacggcccgatcgtgaagcagttggagcgaggcggg
agagccgtggtgaagatggactggcgggagaacatcaccgtccccctccaaacagatctg
cgcaaattccggacctacaaggggggctctgtccgggatctcctccgcgccatgagaaat
aagaaacatcactaccgcgagctgcctgccgaggtgcgcgagacgctgggctcgatcccc
gaggactttgtgcgctacttcacagcccgcttcccccacctcctgtcgcacacctaccgg
gccatggggctctgccgccacgagaggctcttccagccctactactgccagcagcccccc
gacccccagcccccctgcctcccggcagcgccccctgagtcaggacagatgcccctctat
gcacagccccagctagactga
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