Echinops telfairi (small Madagascar hedgehog): 101663486
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Entry
101663486 CDS
T08707
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf04217
Necroptosis
etf04380
Osteoclast differentiation
etf04620
Toll-like receptor signaling pathway
etf04621
NOD-like receptor signaling pathway
etf04630
JAK-STAT signaling pathway
etf04658
Th1 and Th2 cell differentiation
etf04659
Th17 cell differentiation
etf05145
Toxoplasmosis
etf05160
Hepatitis C
etf05161
Hepatitis B
etf05162
Measles
etf05164
Influenza A
etf05165
Human papillomavirus infection
etf05167
Kaposi sarcoma-associated herpesvirus infection
etf05168
Herpes simplex virus 1 infection
etf05169
Epstein-Barr virus infection
etf05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101663486 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101663486 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101663486 (TYK2)
04621 NOD-like receptor signaling pathway
101663486 (TYK2)
04658 Th1 and Th2 cell differentiation
101663486 (TYK2)
04659 Th17 cell differentiation
101663486 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
101663486 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101663486 (TYK2)
05160 Hepatitis C
101663486 (TYK2)
05171 Coronavirus disease - COVID-19
101663486 (TYK2)
05164 Influenza A
101663486 (TYK2)
05162 Measles
101663486 (TYK2)
05168 Herpes simplex virus 1 infection
101663486 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101663486 (TYK2)
05169 Epstein-Barr virus infection
101663486 (TYK2)
05165 Human papillomavirus infection
101663486 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101663486 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101663486 (TYK2)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101663486 (TYK2)
Protein kinases [BR:
etf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101663486 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kdo
Kinase-like
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
101663486
NCBI-ProteinID:
XP_045146268
LinkDB
All DBs
Position
Unknown
AA seq
1164 aa
AA seq
DB search
MPLCQWGATARSSRASGDGAQPVGTGGGLRVLLHWAGPDGGEPWVTFSEGSLTAEDVCLR
IAHRLGITPSCFNLFALFNAQAHIWLPPSHILEVPRDSSLILYFRMRFYFRNWHGMNAQE
QTVYRCGPPGSQASSHPAEGGLQFLDPASFEYIFEQGKHEFVNDVVSLWELSSEEQIRHF
KNESLGMAFLHLCHLALCLGVPLEEVAKKTSFKDCIPRSFRRHIRQRSALTRLRLHNIFR
RFLRAFQPGSLSQQLVMVKYLATLEQLAPRFAAEHVPVCHLELLAQAEGEPSCTLSPGQP
PGDPGPEPATGPPSHELLVTGTEGIQWRPVQAEGSGCSRNPPASPARKKGEAQEVGERPA
PWASFCNFQDISHLVVKEQRVSICRQDNTRLELTLPSRAEALSLVSLVDGYFRLTVDSSH
YLCHEVAPPRLVMNIQNGIHGPLLDPFVLAKLRPEDGHYLIHWSTRHLYRLILTVAQREQ
APSSRSVHLRKFTVEQQAGAFTLEGWDRTFPSIGALRATLQDCSLRAGDHCFSLRHCCLP
RPGELSNLIIMRGPQANARPLNIGQLSFYRVHPDHITQLAHLGQGTRTNVYEGLLRVGGG
SPEEDQEHGGAQELRVVLKVLEPQHHDVALAFYEIASLMSQVSHTHLAFVHGVCVQGSEN
ILVTEYVEHGPLDVWLRRERGRVPVAWKVAVAQQLASALSYLEDKHLVHGSVCGRHILLA
RPGLVEGSSPFIKLSDPGVGLAVLSREERVERIPWLAPECLPGGAPSLSPAVDKWGFGAT
LLEICFDGEAPLQGRSPSEKERFYQKRQQLPEPASPELATLTRQCLTYNPAQRPSFRTVL
RDLTQLQPHNLSDIMAVSPNSLATDPTVFHKRYLKKIRDLGEGHFGKVTLYCYDPTNDGT
GEMVAVKALKAGSGPQLRAGWRREIDILRTLYHEHVVKYKGCCEDPGEKSMQLVMEYVPL
GSLRDYLPRHHVGLAHLLLFARQICEGMAYLHTQHYIHRDLAARNVLLDHGRLVKIGDFG
LAKAVPEGHDYYRVREDGDSPAFWYAPECLKESKFYYASDVWSFGVTLYELLTRCDSSQS
PPSKFMELIGFNPGQMTVLRLTELLEQGERLPRPEACPCEIYHLMKHCWEEEASFRPTFQ
NLIPILNTVQEKYQGQAPSVFNLC
NT seq
3495 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccagtggggggccactgcccgcagcagcagggcatctggggacggagct
cagcccgtgggcacagggggcggtttgcgtgtacttctgcactgggccgggccagacggc
ggggagccctgggtcaccttcagcgaaggctcgctgacagccgaggacgtctgtctccgc
atcgcacacagactcggcatcactccctcctgcttcaatctgttcgccctcttcaatgcc
caggcccacatctggctgcccccaagccacatcctggaggtccccagagacagcagcctc
atcctgtacttccgtatgaggttttatttccggaactggcatggcatgaatgctcaggaa
cagactgtgtaccgctgcgggccccccgggtcccaggcttcctcccatccagcagagggg
ggactgcagttcctagacccagcctcctttgagtacatctttgagcagggcaagcacgag
ttcgtgaatgacgtggtctccctgtgggagctgtccagcgaggagcagatccgccacttc
aagaatgagagcctgggcatggctttcctgcacctctgccacctggcgctctgcctcggt
gtccccctggaggaggtggccaagaagaccagcttcaaggactgcatcccgcgctccttc
cggcgccacatccggcagcgcagcgcgctgacccggctgcgcctgcacaacatcttccgc
cggttcctgcgagccttccagccgggcagcctctcccagcagctcgtcatggtcaagtac
ctggccacgctcgagcagctggcgccccgctttgccgcggagcacgtgcccgtgtgccac
ctggagctgctggcccaggctgagggggagcccagctgcaccctgagccctggacagccc
cctggggacccgggtcctgagcctgccaccggacccccttcccacgaattgctggtgacg
ggcactgagggcattcagtggcggccagtacaggcagagggttctggttgcagcaggaat
ccaccagccagccctgcccggaagaaaggcgaggcccaagaggtgggtgagcggccagca
ccctgggcctccttctgcaacttccaggacatcagccaccttgtggtgaaggaacaacgt
gtcagcatttgccggcaggacaacacacgcctggagctgaccctgccttccagggctgag
gccctgtccttggtgtccctggtggatggctactttcgcctgacagtcgactccagccac
tacctgtgccacgaggtggctcctccccggctggtgatgaatatccagaatggtatccat
ggccccctgctggatccctttgtgctggccaagctccggcctgaggacggtcactacctc
atccactggagcaccaggcacctctaccgcctgatcctcacagtggcccagcgagagcag
gcacccagctccagaagcgtgcacctgcggaagttcacagtggagcagcaggctggagcc
ttcacactggagggctgggaccgaaccttccccagcattggggcgctgcgggccacccta
caagactgctccctgcgtgccggggaccactgcttctctctgcgccactgctgcctgccc
aggccaggagagctctccaaccttatcataatgcggggccctcaggctaatgcccggcca
ctcaacatcggccagctcagcttctaccgggtacacccggaccatatcacccagcttgcc
cacttgggccagggcacgaggaccaacgtgtatgagggcctcctgcgtgtggggggcggg
tcccccgaggaggaccaggagcacgggggtgcccaggagctccgagtggtgctcaaggtg
ctggagccccagcaccacgacgtggccttggccttctatgagatcgccagcctcatgagc
caggtctcccacacacacctggcctttgtgcatggtgtctgcgtgcaaggctctgagaac
atcctggtgaccgagtacgtggagcatggccccctggacgtgtggctgcggcgggagagg
ggccgtgtgcctgtggcctggaaggtggcagtggcccagcagctggccagcgccctcagc
tacctggaggacaagcacctggttcatggcagcgtgtgtggccggcatatcctgctggct
cggcctggcctggtggagggcagcagccccttcatcaagctgagcgaccccggcgtgggc
ctggccgtcctctccagagaggagcgggtggagcggatcccctggctggccccagagtgt
ctacctggtggggctcccagcctgagccccgcggtcgacaagtggggcttcggtgccacc
ctgctggagatctgctttgacggcgaggcccccctgcagggccgcagcccctctgagaaa
gagcgcttctaccagaagcggcagcagctgcccgagcccgcaagcccggagctggccacc
ctcaccaggcagtgcctgacgtacaatccagcccagcggccctccttccgcaccgtcctg
cgagacctcacgcagctgcagccccacaatctttctgacatcatggctgtgagccccaac
tcgctggcaaccgaccccaccgttttccacaagcgctatttgaaaaaaatccgggatctg
ggcgagggccacttcggtaaggttaccttgtactgctacgacccaaccaacgacggcacc
ggcgagatggtcgccgtgaaggccctgaaggcgggcagcggcccccagctccgcgccggc
tggagacgcgagatcgacattctgcgcacgctctaccacgagcacgtggtcaagtacaag
ggctgctgcgaagacccaggcgagaagtccatgcagctggtcatggagtatgtgcctctg
ggcagcctccgggactacctgccccggcaccacgtgggcctggcccacctgctactcttc
gcccggcagatctgcgagggcatggcctacctgcacacgcagcactacatccaccgagac
ctggccgcgcgcaacgtactgctggaccatggcaggctggtcaagatcggggattttggc
ctggccaaagccgtcccagaaggccacgattactaccgcgtgcgcgaggatggggacagc
cctgcgttctggtatgcccccgagtgcctgaaggagtccaagttctactatgcgtctgac
gtgtggtccttcggggtcaccctgtatgagctgctgacacgctgtgactccagccagagc
cccccttcgaaattcatggaactcattggcttcaacccgggtcagatgacggtgctgagg
ctcacggagttactagaacaaggagagcggttgcctcgaccagaggcatgtccctgtgag
atctatcacctcatgaagcactgctgggaagaggaggcctccttccgcccgaccttccag
aacctcatccccatcctcaacactgttcaggagaaataccaaggccaggccccctccgtg
ttcaacctgtgctga
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