Echinops telfairi (small Madagascar hedgehog): 101664197
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Entry
101664197 CDS
T08707
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
etf
Echinops telfairi (small Madagascar hedgehog)
Pathway
etf01521
EGFR tyrosine kinase inhibitor resistance
etf04151
PI3K-Akt signaling pathway
etf04217
Necroptosis
etf04380
Osteoclast differentiation
etf04550
Signaling pathways regulating pluripotency of stem cells
etf04620
Toll-like receptor signaling pathway
etf04621
NOD-like receptor signaling pathway
etf04630
JAK-STAT signaling pathway
etf04658
Th1 and Th2 cell differentiation
etf04659
Th17 cell differentiation
etf05140
Leishmaniasis
etf05145
Toxoplasmosis
etf05152
Tuberculosis
etf05160
Hepatitis C
etf05161
Hepatitis B
etf05162
Measles
etf05163
Human cytomegalovirus infection
etf05164
Influenza A
etf05165
Human papillomavirus infection
etf05166
Human T-cell leukemia virus 1 infection
etf05167
Kaposi sarcoma-associated herpesvirus infection
etf05168
Herpes simplex virus 1 infection
etf05169
Epstein-Barr virus infection
etf05171
Coronavirus disease
etf05200
Pathways in cancer
etf05203
Viral carcinogenesis
etf05212
Pancreatic cancer
etf05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
etf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101664197 (JAK1)
04151 PI3K-Akt signaling pathway
101664197 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101664197 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101664197 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101664197 (JAK1)
04621 NOD-like receptor signaling pathway
101664197 (JAK1)
04658 Th1 and Th2 cell differentiation
101664197 (JAK1)
04659 Th17 cell differentiation
101664197 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
101664197 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101664197 (JAK1)
05203 Viral carcinogenesis
101664197 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101664197 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
101664197 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101664197 (JAK1)
05161 Hepatitis B
101664197 (JAK1)
05160 Hepatitis C
101664197 (JAK1)
05171 Coronavirus disease
101664197 (JAK1)
05164 Influenza A
101664197 (JAK1)
05162 Measles
101664197 (JAK1)
05168 Herpes simplex virus 1 infection
101664197 (JAK1)
05163 Human cytomegalovirus infection
101664197 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
101664197 (JAK1)
05169 Epstein-Barr virus infection
101664197 (JAK1)
05165 Human papillomavirus infection
101664197 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
101664197 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101664197 (JAK1)
05140 Leishmaniasis
101664197 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101664197 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
etf01001
]
101664197 (JAK1)
Enzymes [BR:
etf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101664197 (JAK1)
Protein kinases [BR:
etf01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101664197 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
101664197
NCBI-ProteinID:
XP_012859286
UniProt:
A0ABM0ZPM8
LinkDB
All DBs
Position
Unknown
AA seq
1158 aa
AA seq
DB search
MQFLNIKEDCNAMAFCAKMRSSKKTEVNLEAPQPGVAVIFYLPDREPLRLGSGEYTAEEL
CIRAAQECRISPLCYNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYERKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPQTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPRDISYKRYIPETLNKSIRQRNVLTRLRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAELFETAMLLISSENEVM
NRFHSNDSGNFLCYEVMVTGNLGIQWRQKPIVLPVEKEKNKLKRKKLDHKYKKDEEKNKI
RDEWNNFSYFPEITHIVIKESAVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADA
HHYLCTDVAPPLIVHNIQNGCHGPISTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTV
TCFEKSEQVLGGQKQFKNFQIEVQKGQYSLHGSAHSFPSLGELMGHLKKQILRTDNISFV
LKRCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIIQGEHLGRGTRTHIYS
GTLLDYKDEEGISEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVR
DVENIMVEEFVEGGPLDLFMHRKSDALTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKN
LLLAREGIDSEYGPFIKLSDPGIPITVLTRQECIERIPWIAPECVEDSKNLSVAADKWSF
GTTLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPSQRPFFR
AIMRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGD
NTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFL
PSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKI
GDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCD
SDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDQVYQLMRKCWEFQPSSR
TTFQNLIEGFEALLKQEA
NT seq
3477 nt
NT seq
+upstream
nt +downstream
nt
atgcagtttctcaacatcaaggaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagacagaggtgaacctggaggccccgcagcccggggtggcggtgatcttc
tacctgcctgacagggagccgctccggctgggcagcggagagtacacggcggaggagctg
tgcatccgggctgcacaagagtgccgtatttctcctctgtgttacaacctctttgccctg
tacgatgagaacaccaagctgtggtacgctccgaaccgcaccatcactgtggatgacaag
acgtccctgcggctccactaccggatgaggttctatttcaccaactggcatgggaccaac
gacaatgagcagtcagtgtggcgacattctccaaagaagcagaaaaatggctatgagaga
aaaaaagtcccggatgctacccctctccttgatgccagttcactggagtatctgtttgct
cagggacagtacgatttggtcaaatgcctggctcccatccgggacccccagacagagcag
gatgggcatgacatcgagaacgagtgtctgggaatggcagtcctggccatctcacactat
gccatgatgaagaagatgcagttgccagagcttcccagggacatcagctacaagcgatat
attccagaaacactgaataagtccatccgacagaggaatgtccttaccaggttgcgaatc
aacaacgttttcaaggatttcctaaaggaatttaacaacaagaccatctgcgacagcagc
gtgtccacgcacgacctgaaggtgaaatacttggcgacgttggagacgttgacgaagcat
tacggtgctgagctctttgagaccgccatgctactgatctcatcagaaaatgaggtgatg
aatcggtttcattccaacgacagtggaaactttctctgctatgaagtgatggtgactgga
aacctcgggatccagtggcggcagaagccaatcgttcttcctgttgagaaggaaaaaaac
aagctgaagcggaaaaaactggatcacaaatacaagaaggatgaggagaaaaataaaatc
cgggacgagtggaacaatttttcttactttcctgaaattactcacattgtaataaaagag
tctgcggtcagcattaacaagcaggacaacaaaaagatggaactgaagctctcttcccac
gaggaggccttgtcctttgtgtctctggtcgacggctacttccggctcacagcagatgct
catcattacctctgcaccgatgtggctcccccgttgatcgtccacaacatacagaacggg
tgtcacggcccaatcagcacagaatacgccatcaacaaattgcggcaagaaggaagcgag
gagggcatgtacgtgctgaggtggagctgcaccgacttcgacaacatcctcatgaccgtc
acctgctttgaaaagtctgagcaggtgctgggcggccagaagcagttcaagaacttccag
atcgaggtgcagaaggggcagtacagcctgcacggctcggcgcacagcttccccagcctg
ggggagctcatgggccacctcaagaagcagatcctgcgcacggacaacatcagcttcgtg
ctgaagcgctgctgccagcccaagccccgagaaatctcaaatctgctggtggctaccaag
aaggctcaggagtggcagcccgtctaccccatgagccaactgagtttcgaccggatcctc
aagaaagatattatacaaggtgagcacctcgggagaggcacacggacacacatttactca
gggaccctgctggattacaaggatgaggaggggatttccgaagagaagagaatcaaagtg
atcctcaaagtcttggaccccagccacagggacatttctctggccttcttcgaggcagcc
agcatgatgagacaggtctcccacaagcacatcgtgtacctctatggcgtctgtgtccga
gatgtggagaatatcatggtggaagagtttgtggaggggggacccctggatctcttcatg
caccggaaaagtgatgccctcaccacaccatggaagttcaaagttgccaaacagctagcc
agcgccctgagttacttggaggataaagacctggtccatggaaacgtgtgcacgaaaaac
ctgctcctggcccgtgaaggcatcgacagcgagtacggtccattcatcaagctcagtgac
cccggcatccccatcactgtcctgacccggcaagagtgcatagaacgaatcccgtggatt
gcgcccgagtgtgttgaagactccaagaacctgagcgtggccgctgacaagtggagcttc
ggaaccaccctgtgggaaatctgctacaacggcgagatccccctgaaagacaagacgctg
attgagaaagagcgattctacgagagccggtgcagaccagtgaccccatcctgcaaggag
ctggccgacctgatgacgcgctgcatgaactacgaccccagccagagaccgttcttccga
gccatcatgagagacattaacaagcttgaggagcagaatccagacattgtttcagaacga
aaaccagcaactgaagtggatcccacacattttgaaaagcgattcctaaagcggatccgt
gacttgggagagggccacttcgggaaggttgagctctgcaggtatgaccccgagggggac
aatactggagagcaggtggctgtcaaatccctgaagcccgagagtggaggcaaccacatt
gctgacctaaagaaagaaattgaaatcttaaggaacctctaccatgagaacatcgtgaag
tacaaaggcatctgcacagaagacggaggaaacggtattaagctcatcatggaatttctg
ccatctggaagccttaaggagtatcttcccaagaataagaacaaaatcaaccttaaacag
cagctaaaatatgctgtgcagatttgcaaggggatggactacctgggttcccgccagtat
gtgcaccgggatttagcggcaagaaatgtccttgttgagagtgagcaccaagtgaagatc
ggagactttggtttgaccaaagcaatagaaactgacaaggagtactacacggtcaaggat
gatcgggacagccccgtgttttggtatgctccagaatgtttaattcagtgtaaattttac
atcgcctctgacgtctggtccttcggcgtgaccctgcacgagctgctgacgtactgtgac
tcggactccagtcccatggcgttgttcctgaaaatgatcggcccaactcacggccagatg
actgtaacgagacttgtgaatacattgaaagaaggaaaacgtctgccgtgcccaccgaac
tgcccagatcaggtttatcagctgatgaggaaatgctgggaattccagccatccagtcgg
acaacctttcagaaccttattgaaggatttgaagcacttttaaaacaggaagcatga
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integrated database retrieval system
