Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_0076
Help
Entry
ECUMN_0076 CDS
T00831
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00290
Valine, leucine and isoleucine biosynthesis
eum00620
Pyruvate metabolism
eum01100
Metabolic pathways
eum01110
Biosynthesis of secondary metabolites
eum01210
2-Oxocarboxylic acid metabolism
eum01230
Biosynthesis of amino acids
Module
eum_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ECUMN_0076 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECUMN_0076 (leuA)
Enzymes [BR:
eum01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ECUMN_0076 (leuA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
CAR11299
UniProt:
B7N7U9
LinkDB
All DBs
Position
complement(86644..88215)
Genome browser
AA seq
523 aa
AA seq
DB search
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRATEVEKELQRKAQHNENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcttgagtgtgaaagaaaaactgcaaattgcgctggcccttgagcgtatgggtgtt
gacgtgatggaagtcgggttccccgtctcttcgccgggtgattttgaatcagtgcaaacc
atcgctcgccaggttaaaaacagccgcgtatgcgcgttagctcgctgcgtggaaaaggat
atcgacgtggcggccgaatctctgaaagtcgccgaagccttccggattcatacctttatt
gccacttcgccaatgcacattgccaccaagctgcgtagcacgctggacgaggtgatcgaa
cgcgctatctatatggtgaaacgcgcccgtaattacaccgatgatgttgaattttcttgc
gaagatgccggacgcaccccaattgccgatctggcgcgagtggtcgaagcggcgattaat
gccggtgccaccaccatcaacatcccggacaccgtgggctacaccatgccatttgagttc
gccggaatcatcagcgggctgtatgaacgcgtacccaacatcgacaaagccattatttcc
gtacatacccacgacgatttgggcctggcggtcggaaactcactggcggcggtacatgcc
ggtgcacgccaggtggaaggtgcaatgaacgggatcggcgagcgtgccggtaactgttcc
ctggaagaagtgatcatggcgatcaaagttcgtaaggatattctcaacgttcataccgcc
attaatcaccaggaaatatggcgcaccagccaattagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgcattcgcacactcctccggtattcat
caggatggtgtgctgaaaaaccgcgaaaactacgaaatcatgacaccagaatctattggt
ttgaaccaaatccagctgaatctgacctctcgttcgggacgtgcggcagtaaaacaccgc
atggatgagatggggtataaagaaagtgaatataatttagacaatttgtacgatgccttc
ctgaagctggcggacaaaaaaggtcaggtgtttgattacgatctggaggcactggccttc
atcggtaagcagcaagaagagccggagcatttccgtctggattacttcagcgtgcagtct
ggctctaacgatattgccactgccgccgtcaaactggcctgcggcgaagaagtcaaagca
gaagccgccaacggtaacggtccggtcgatgccgtctatcaggcgataaaccgcatcact
gactataacgtcgaactggtgaagtacagcctgaccgccaaaggccacggtaaagatgcg
ctgggtcaggtggatattgtcgccaactacaatggtcgccgcttccacggcgtcggcctg
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtacttaacaatatctgg
cgtgccacagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag
gaaaccgtgtga
DBGET
integrated database retrieval system
