Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_1573
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Entry
ECUMN_1573 CDS
T00831
Symbol
topA
Name
(GenBank) DNA topoisomerase I, omega subunit
KO
K03168
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
eum03032
]
ECUMN_1573 (topA)
03400 DNA repair and recombination proteins [BR:
eum03400
]
ECUMN_1573 (topA)
Enzymes [BR:
eum01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
ECUMN_1573 (topA)
DNA replication proteins [BR:
eum03032
]
Prokaryotic type
DNA Topoisomerases
ECUMN_1573 (topA)
DNA repair and recombination proteins [BR:
eum03400
]
Prokaryotic type
DSBR (double strand breaks repair)
NHEJ (non-homologous end-joining)
SHIIR (short-homology-independent illegitimate recombination)
Facilitator
ECUMN_1573 (topA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_Ribbon_Topo
Zn_ribbon_bTOP1
Toprim
Zn_ribbon_Top1
Zn_ribbon_recom
Toprim_4
DUF4795
Motif
Other DBs
NCBI-ProteinID:
CAR12780
UniProt:
B7N487
LinkDB
All DBs
Position
1582881..1585478
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AA seq
865 aa
AA seq
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MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPK
KDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIA
WHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNIDRVNAQQARRFMDRVVGYMVS
PLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGDALALQVTH
QNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFG
VKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKEN
SQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVACQMTPAKYDSTTLTVGAGDF
RLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEA
SLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNY
DFTAQMENSLDQVANHEAEWKAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCP
TCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPENEVLNVLEGEDAETNALRAKR
RCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHL
KMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVF
LAANTFPKSRETRAPLVEELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYV
SSEKDGKATGWSAFYVDGKWVEGKK
NT seq
2598 nt
NT seq
+upstream
nt +downstream
nt
atgggtaaagctcttgtcatcgttgagtccccggcaaaagccaaaacgatcaacaagtat
ctgggtagtgactacgtggtgaaatccagcgtcggtcacatccgcgatttgccgaccagt
ggctcagctgccaaaaagagtgccgactctacctccaccaagacggctaaaaagcctaaa
aaggatgaacgtggcgctctcgtcaaccgtatgggggttgacccgtggcacaattgggag
gcgcactatgaagtgttgcctggtaaagagaaggtcgtctctgaactgaaacaactggct
gaaaaagccgaccacatctatctcgcaaccgaccttgaccgcgaaggggaagccattgca
tggcacctgcgggaagtgattggtggtgatgatgcgcgctatagccgagtggtgtttaac
gaaattactaaaaacgcgatccgccaggcatttaacaaaccaggtgagctgaatattgat
cgtgttaatgcccagcaggcgcgtcgctttatggaccgcgtggtgggatatatggtttcg
ccgctgctgtggaaaaagatcgctcgtggtctgtctgcaggtcgtgtgcagtcggtggcg
gtccgcctggtggtcgagcgtgagcgtgaaattaaagcgttcgtaccggaagagttctgg
gaagtcgatgccagcacgaccacgccatctggtgatgcgttggcgttgcaggtgactcat
cagaacgacaaaccgttccgcccggtcaacaaagaacaaactcaggctgcggtaagtctg
ctggaaaaagcgcgctacagcgtgctggaacgtgaagacaaaccgacaaccagtaaacct
ggcgctccttttattacctctacgctgcaacaagctgccagcacccgtcttggttttggc
gtgaaaaaaaccatgatgatggcgcagcgtttgtatgaagctggctatatcacatacatg
cgtaccgactccaccaacctgagtcaggacgcggtaaatatggttcgcggttatatcagc
gataattttggtaagaaatatctgccggaaagtccgaatcagtacgccagcaaagaaaac
tcacaggaagcgcacgaagcgattcgtccttctgacgtcaatgtgatggcggaatcgctg
aaggatatggaagcagatgcgcaaaaactgtaccagttaatctggcgtcagttcgttgcc
tgccagatgaccccagcgaaatatgactccacgacgctgaccgttggtgcgggcgatttc
cgcctgaaagcacgcggtcgtattttgcgctttgatggctggacaaaagtgatgcctgca
ctgcgtaaaggcgatgaagatcgtatcttaccggcagtcgataaaggcgatgctctgacg
ctcgttgaactgacaccagcccagcactttaccaagccgccagcgcgtttcagtgaagca
tcgttggttaaagaactggaaaaacgcggtatcggtcgtccgtctacctatgcgtcgatc
atttcgactattcaggatcgtggctatgtgcgagtagaaaatcgtcgtttctatgcggaa
aaaatgggcgaaatcgtcaccgatcgcctggaagagaatttccgtgagttaatgaactac
gacttcaccgcacagatggaaaacagcctcgaccaggtggcaaatcacgaagcagagtgg
aaagctgtactggatcacttcttctcggatttcacccagcagttagataaagctgaaaaa
gatccggaagagggggggatgcgcccgaaccagatggttctgaccagcatcgactgcccg
acctgtggtcgcaaaatgggtattcgcacagcgagcaccggggtattccttggctgttcc
ggctacgctctgccaccgaaagagcgttgcaaaaccaccatcaacctggtgccggaaaac
gaagtgctgaacgtgctggaaggtgaagacgctgaaaccaacgcgctgcgcgcaaaacgt
cgttgcccgaaatgcggcacggcgatggacagctatctcatcgatccgaaacgtaagttg
catgtctgtggtaataacccaacctgcgacggttacgagatcgaagagggcgaattccgc
attaaaggttatgacggcccgatcgttgagtgtgaaaaatgtggatctgaaatgcacctg
aaaatggggcgtttcggtaaatacatggcctgcactaacgaagagtgtaaaaacacgcgt
aagattttacgtaacggcgaagtggcaccaccgaaagaagatccggtgccattaccggag
ctgccgtgcgaaaaatcagatgcttatttcgtgctgcgtgacggtgctgccggtgtgttc
ctggcggccaataccttcccgaaatcgcgtgaaacacgtgcgccactggtggaagagctt
tatcgcttccgcgaccgtctgccggaaaaactgcgttatctggccgatgcgccacagcag
gatccggaaggtaataagaccatggttcgctttagccgtaaaaccaaacagcaatatgtc
tcttcggaaaaagacggaaaggcgactggctggtcagcattttatgttgatggcaaatgg
gttgaagggaaaaaataa
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