Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_2877
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Entry
ECUMN_2877 CDS
T00831
Symbol
purL
Name
(GenBank) phosphoribosylformyl-glycineamide synthetase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00230
Purine metabolism
eum01100
Metabolic pathways
eum01110
Biosynthesis of secondary metabolites
Module
eum_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECUMN_2877 (purL)
Enzymes [BR:
eum01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ECUMN_2877 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CAR14053
UniProt:
B7N6E4
LinkDB
All DBs
Position
complement(2983176..2987063)
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AA seq
1295 aa
AA seq
DB search
MMEILRGSPALSAFRINKLLARFQAARLPVHTIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTREVQTLKAKGDALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAVQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGIDADIATLGDDRLAALFNEELGAVIQVRAADRKAVEAVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcattgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacactatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggcccggcactcgccagccatgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggctg
caacaggtaaaccgtcttgagcgcggcgtggcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagctgtttgcacaccatcaaccgactccggtcaccagc
gttgatttgctgggacagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaatcgactatctgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgagctgtatatgttcgctcaggcgaactctgagcactgccgccacaaa
atttttaacgccgactggattatcgacggtgaacagcagccgaaatcgctgttcaagatg
atcaaaaataccttcgaaactacgccggatcacgttctctctgcttataaagataacgcc
gccgtcatggaagggtctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgtggcgcaaagccgaaagctggtctggtaggtttctccgtttccaacctg
cgaattccaggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgttggacatcatgaccgaaggcccgctgggcggcgcggcatttaacaacgaattt
ggtcgtccggcactgaacggctacttccgtacttatgaagaaaaagtgaacagccacaat
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacatt
cgtgccgatcacgtacaaaaaggcgagatcaacgttggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggcgcggcgtcttccatggcgtctggtcag
tctgatgccgacctcgacttcgcttccgtacagcgcgacaacccggagatggagcgtcgc
tgccaggaagtgatcgaccgttgctggcagcttggtgatgccaacccaatcctgtttatc
cacgacgttggcgcaggcggtctttctaacgccatgccggaactggtgagcgacggcggg
cgcggcggtaaattcgaactgcgcgatatcctgagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcagtta
ccgctgtttgacgaactgtgtaagcgtgagcgcgcgccatacgcggtgattggtgaagcg
accgaagaactgcatctttctttgcacgatcgtcattttgataatcagccgatcgatctg
ccgctggacgtcctgcttggtaaaacgccgaagatgacccgcgaagtacaaacgctgaaa
gcgaagggtgatgcgctggttcgtgaagggattaccattgctgacgcggtgaaacgcgtg
ctgcacctgccgaccgtggcggagaaaactttcctggtgaccattggtgaccgcagcgta
accggcatggtagcgcgcgatcagatggtgggtccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgatagctactacggcgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggcgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggtcatccaggcgaagatgcgggcctgtatgaagccgttaaagctgtg
ggcgaagaactttgtccggctctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccactgtcgctg
gttatttctgcatttgcccgcgtggaagatgtacgtcacaccatcacgccacagctttct
accgaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtc
gcgcaactgaaaggtttctatgacgcggttcaggcgctggtagcacagcgtaagctgctc
gcgtaccacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgcggcattgacgcggatatcgccactctgggtgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggttcgagccgctgaccgtaaagcagttgaa
gcggtactggcacagcatggccttgctgattgcgtccattatgttggccaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaaccctgaa
tgtgccgatcaggaacatcaggcgaaatccaacgacgccgatccgggcctgaatgtgaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtatattgctactggcgcacgtccg
aaagttgccgtactgcgtgagcagggcgtgaactcgcatgttgaaatggcggctgctttc
caccgtgcaggcttcgatgcaatcgatgtgcatatgagtgacctgctggctggacgcacg
ggcctggaggatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtctatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaatctgcgcgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcctggttgaagtaacccaaagcccgtctctg
ctgttgcaggggatggtgggctcgcaaatgccgattgctgtatctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgtcgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttct
ccgaatggtattacggcagtcacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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