Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_4297
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Entry
ECUMN_4297 CDS
T00831
Symbol
ilvD
Name
(GenBank) dihydroxyacid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00290
Valine, leucine and isoleucine biosynthesis
eum00770
Pantothenate and CoA biosynthesis
eum01100
Metabolic pathways
eum01110
Biosynthesis of secondary metabolites
eum01210
2-Oxocarboxylic acid metabolism
eum01230
Biosynthesis of amino acids
Module
eum_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
eum_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ECUMN_4297 (ilvD)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
ECUMN_4297 (ilvD)
Enzymes [BR:
eum01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
ECUMN_4297 (ilvD)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
CAR15433
UniProt:
B7NF78
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Position
4440346..4442196
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQ
SDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQT
LEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDSLDDDRANGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKVCALITDGRFSGGTSGLSIGHVSPEAASGGSIGL
IEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccactcatggtcgtaatatggcgggtgctcgtgcg
ctgtggcgcgccaccggaatgaccgacgccgatttcggtaagccgattatcgcggttgtg
aactcgttcacccaatttgtaccgggtcacgtccatctgcgcgatctcggtaaactggtc
gccgaacaaattgaagcggctggcggcgttgccaaagagttcaacaccattgcggtggat
gatgggattgccatgggccacggggggatgctttattcgctgccatctcgcgaactgatc
gctgattccgttgagtatatggtcaacgctcactgcgccgacgccatggtctgcatctct
aactgcgacaaaatcaccccggggatgctgatggcttccctgcgcctgaatattccggtg
atctttgtttccggcggcccgatggaggccgggaaaaccaaactgtccgatcagatcatc
aagctcgatctggttgatgcgatgatccagggcgcagacccgaaagtttctgactcccag
agcgatcaggttgaacgttccgcgtgtccgacctgcggctcctgctccgggatgtttacc
gctaactcaatgaactgcctgaccgaagcgctgggcctgtcgcagccgggcaacggctcg
ctgctggcaactcacgccgatcgtaagcagctgttcctcaatgccggtaaacgcattgtt
gaattgaccaaacgttactacgagcaaaatgacgaaagtgcactgccgcgcaatattgct
agcaaagcggcgtttgaaaacgccatgacgttggatatcgcaatgggcggctctaccaac
accgtacttcacctgctggcggcggcgcaggaagcggaaatcgacttcaccatgagtgat
atcgacaaactttcgcgtaaagtcccgcagttatgtaaagttgcgccgagcacccagaaa
taccatatggaagatgttcaccgtgctggtggtgttatcggtattctcggcgaactggat
cgcgcggggttactgaaccgtgatgtgaaaaacgtacttggcctgacgttgccgcaaacg
ctggaacaatacgacgttatgctgacccaggatgacgcggtaaaaaatatgttccgcgca
ggcccggcaggcattcgtaccacacaggcattctcgcaggattgccgttgggattctctc
gatgacgatcgcgcaaacggctgtatccgctcgctggaacacgcctacagcaaagacggt
ggccttgcggtgctctacggtaatttcgcagaaaacggctgcatcgttaaaaccgcgggc
gtcgatgacagcatcctcaaattcaccggtccggcgaaagtgtacgaaagccaggatgac
gcggtagaagcgattctcggcggcaaagttgtcgctggcgatgtggtggtgatccggtac
gaaggtccgaaaggcggtccggggatgcaggaaatgctctacccaaccagcttcctgaaa
tcaatgggtctcggtaaagtctgcgcgctgatcaccgacggacgcttctccggcggcacc
tctggtctttccatcggccacgtctcgccggaagcggcaagcggcggcagcattggtctg
attgaagacggcgatcttatcgctatcgacattccgaatcgtggcattcagttacaggta
agcgatgccgaactggcggcgcgtcgtgaagcgcaggaagctcgtggcgacaaagcctgg
acgccgaaaaatcgcgaacgtcaggtctcctttgcattgcgcgcctacgccagcctggca
accagcgccgacaaaggtgcggtgcgcgataaatcgaaactggggggttaa
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