Eggerthella sp. YY7918: EGYY_18170
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Entry
EGYY_18170 CDS
T01566
Symbol
LeuA
Name
(GenBank) isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
eyy
Eggerthella sp. YY7918
Pathway
eyy00290
Valine, leucine and isoleucine biosynthesis
eyy00620
Pyruvate metabolism
eyy01100
Metabolic pathways
eyy01110
Biosynthesis of secondary metabolites
eyy01210
2-Oxocarboxylic acid metabolism
eyy01230
Biosynthesis of amino acids
Module
eyy_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eyy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EGYY_18170 (LeuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EGYY_18170 (LeuA)
Enzymes [BR:
eyy01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EGYY_18170 (LeuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Cep57_CLD_2
TM_PBP2_N
Motif
Other DBs
NCBI-ProteinID:
BAK44952
UniProt:
F7UUS9
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Position
complement(1968823..1970355)
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AA seq
510 aa
AA seq
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MTRKINIFDTTLRDGEQSPGASMNTEEKLVVARQLLRLNVDIIEAGFPISSPGDFESVRR
VAELAGDKAIVCGLTRAVEKDIDSAADALKYAKRPRIQTGLGVSPSHLHDKLRITEDECV
ERAVKCVKYAKKFVEDVQFYAEDAGRSDYAFLARVIEAVIKAGATVVNIPDTTGYSLPEE
YGARIKYLMDNVDGIDDVTVSVHCHNDLGMATALSLAGVRNGATQVECTINGLGERAGNT
AMEEVVMGIKMHGEELDGHTDINTREFMKASRLVSSITGMSVQANKAIVGANAFAHSSGI
HQDGVLKKRDTYEIIDPAEVGAGQSQIVLTARSGHAALKHRLDELGYELEGAALDQVYEA
FLDLADKKKEVYDEDLESLVNERDRNETALYALEGVQISCGFPLTPTATVTLRNQADQVV
TACEYGTGPVDAMCKAVNKIVQVDNDLTEFSVQSVTRGIDALGEVTIRVTDPDGEVYTGR
GADGDIIVSSTKAYLNALNRLLGDKLEHRK
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgactcgcaagattaacatcttcgacaccacattgcgcgacggcgagcagtcgccgggc
gcatccatgaacaccgaggagaaactggttgttgcgcgtcagcttctacgccttaatgtc
gacatcattgaagccggtttccccatttcgagtcctggcgacttcgagtctgttcgccgc
gtcgccgaactggcgggcgacaaggctattgtctgcggtctgacgcgtgcggtcgaaaag
gacatcgattcggcggccgacgcactcaagtacgccaaacgtccccgcatccagacgggt
cttggcgtgagccccagccacttgcacgataagctgcgcatcaccgaagatgaatgcgtc
gagcgcgcggtcaagtgcgtgaagtatgcaaagaagttcgtcgaggacgtgcagttctac
gccgaggatgcgggccgctcggactacgctttccttgcgcgcgtaatcgaggcggtcatc
aaggccggtgcgacggtggtgaacatccccgacacgacaggctattcgctacccgaggaa
tacggtgcgcgcatcaagtatctcatggataacgtggacggcatcgacgacgtcaccgtg
tccgtgcattgccacaacgacctgggtatggccacggcgctgtcgcttgcaggcgtgcga
aatggcgcgacgcaggttgagtgcaccatcaacggcctgggagagcgcgcaggaaacacg
gccatggaagaagtggtcatgggcataaaaatgcacggcgaggaactggacgggcatacc
gacatcaacacgcgcgaattcatgaaggcaagccgtcttgtgtcgtctatcacgggcatg
agcgtgcaggctaataaggccatcgtgggcgcaaatgcgttcgcccattcttcgggcatt
catcaggacggcgtgctgaagaagcgcgacacctacgagattatcgacccggctgaggtc
ggtgccggccagagccagattgtgctcacggcgcgcagcggacatgcggcgctcaagcat
cgcttggacgagttgggctacgagcttgagggtgcggccctcgatcaggtctacgaggcc
ttcctcgatctggccgacaagaagaaggaagtctacgacgaggatttggaaagccttgtt
aacgagcgtgatcgtaacgagacggctctttatgcgcttgagggtgtgcagatcagctgc
ggtttcccgcttacgcctacggcgacggttaccctgcgcaaccaggccgaccaggtggtt
accgcttgcgagtacggcaccggtccggtggatgccatgtgcaaggcagtcaacaagatc
gtgcaggtggacaacgacctgaccgagttctcggtacaatccgtcacgcgcggcatcgat
gcgctcggcgaggtaaccattcgcgtgaccgatcccgacggggaagtgtacacgggacgc
ggtgcggacggcgacatcatcgtttcgtccacaaaggcctacctcaacgcgcttaaccgt
ctgctcggcgataagcttgagcatcgcaaataa
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