Fibrella aestuarina: FAES_0878
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Entry
FAES_0878 CDS
T02429
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fae
Fibrella aestuarina
Pathway
fae00300
Lysine biosynthesis
fae00550
Peptidoglycan biosynthesis
fae01100
Metabolic pathways
fae01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fae00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
FAES_0878
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
FAES_0878
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
FAES_0878
Enzymes [BR:
fae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
FAES_0878
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
FGGY_C
Motif
Other DBs
NCBI-ProteinID:
CCG98889
UniProt:
I0K436
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Position
1100726..1102030
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AA seq
434 aa
AA seq
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MLTTAALYEKYRECTTVSTDTRQIAPDCLFVALRGDKFDGNQFALQALEAGARYALVDNA
DVAAQHDRCLLVADTLLALQELARHHRRTFGFPVLGLTGSNGKTTTKELIAAVLAKKYAV
EATHGNLNNHIGVPLTLLRIDPARCQLAVVEMGANHQREIDLLSRICEPTHGLITNVGKA
HLEGFGGVEGVRKGKGELFDYLAETGGTVFVNAQNAVLMAMQAERSTRTPNFGNVVFYLT
DNVPELLTEAPVATYRTATGEVIQTHLPGRYNFENVAAALAIGQYFGVPDADANQAVADY
NPTNNRSQVVVRGTNTVLLDAYNANPSSMAAAVQQFGQMPAERKAVILGDMYELGDESPA
EHAALGTLIAQQHFDLVILAGKDMQYALPSLPQAYYFPDKFSLHNWIMDNPMQHTHVLIK
GSRGMGLESVLPFI
NT seq
1305 nt
NT seq
+upstream
nt +downstream
nt
atgctgaccacagcagctttatacgagaagtaccgggaatgtaccaccgtttcgaccgat
acccgccaaatcgcgcccgattgcctgtttgtggccctgcgcggcgataagttcgacggc
aaccagtttgccctacaggcgctggaggccggggcccgctacgcgctggtcgacaatgcc
gacgtggccgctcagcacgaccgctgcctgttggtggccgatacgctgctagccttgcag
gaactggcccggcaccaccgtcgtacgtttggtttcccggttttgggcctgaccggctcg
aacggtaaaaccaccaccaaagagctgattgcggcggtgctagccaaaaaatacgcggtt
gaggccacgcatggtaacctcaacaaccacattggcgtgccgcttaccctgctgcgcatc
gaccctgcccgctgccagctggcggtggtggagatgggggccaatcaccagcgcgaaatc
gatctgctgagccggatctgcgaacccacccacgggctgattactaacgtgggcaaagcg
catctggaaggttttggcggagtcgaaggcgtgcggaaaggcaagggtgaactcttcgac
tacctggccgaaacaggcgggaccgtgttcgtcaacgcgcagaacgccgtgctgatggcc
atgcaggccgagcgcagcacccgaacccccaactttggtaacgtcgttttttacctgacc
gacaacgtacctgaactgctgactgaagcgccggtggcgacgtaccggacggccacgggc
gaggtgatccagacgcatctgccgggtcgctacaactttgagaacgtggcggcggcactg
gctatcgggcagtatttcggtgtgcccgacgccgatgccaatcaggccgtggccgactac
aacccgaccaacaaccggtcgcaggtggtagtgcgcggtaccaacaccgtactgctggat
gcctacaacgccaacccgtcgtcgatggcagcggcggtgcagcagtttgggcaaatgccc
gccgaacgcaaggcggttatcctgggcgatatgtacgaactgggcgacgaaagccctgcc
gagcacgccgccctgggtacgttgattgcccagcagcacttcgatctggtcattctggcg
ggcaaagacatgcagtatgcgttgccttccctgccccaagcctactacttccccgacaag
ttttcgctgcacaactggatcatggataaccccatgcaacatacccacgtgttaattaaa
gggtcgcgcggcatgggattagaaagtgtgcttccgtttatttag
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