Flavobacterium branchiophilum: FBFL15_0978
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Entry
FBFL15_0978 CDS
T01625
Symbol
thrA2
Name
(GenBank) Bifunctional enzyme : aspartate kinase/homoserine dehydrogenase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
fbr
Flavobacterium branchiophilum
Pathway
fbr00260
Glycine, serine and threonine metabolism
fbr00261
Monobactam biosynthesis
fbr00270
Cysteine and methionine metabolism
fbr00300
Lysine biosynthesis
fbr01100
Metabolic pathways
fbr01110
Biosynthesis of secondary metabolites
fbr01120
Microbial metabolism in diverse environments
fbr01230
Biosynthesis of amino acids
Module
fbr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
fbr_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
fbr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FBFL15_0978 (thrA2)
00270 Cysteine and methionine metabolism
FBFL15_0978 (thrA2)
00300 Lysine biosynthesis
FBFL15_0978 (thrA2)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FBFL15_0978 (thrA2)
Enzymes [BR:
fbr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FBFL15_0978 (thrA2)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FBFL15_0978 (thrA2)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Gp_dh_N
DALR_1
BTHB
Motif
Other DBs
NCBI-ProteinID:
CCB69077
UniProt:
G2Z7H1
LinkDB
All DBs
Position
complement(1144646..1147084)
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AA seq
812 aa
AA seq
DB search
MKVLKFGGKSLANGEGLQKVVAIIADKISQNEAITVVVSARGNATNELEHLLQIAAQNGN
YKTLFEDFKNYQIAGYQNIISENNPYKIAIQEEFDILEKLFEGVSLIGDFSPKIKDQILS
KGELLAAKLLTAILLHQGINAQLADARDLIKTDSNFGDAQPLENLSKKNVIQFFKDNAEK
INIVTGFIGSNSNNDATTLGRNGSNYTASLIANFLDASELQNYTHVDGIYTANPELVLDA
KKIDHLSFNEANELANFGATILHAKTIIPLLEKNIPLRILNTFNYENKGTLITSKTEKEG
IKTLSVIENVSLVNLEGRGLLGKAGVDARIFRVMAENQISVSIISQGSSERGIGLVVASD
KASTAMIALEKEFENDFYSKDVNKISVTDNVSIISIIGQDLSSFHKPYTALIKNKIIPIL
FNNTVTGKNVSLVVDKNQLNKALNVIHGEIFGVSKKINIAIFGHGLVGGTLINQILESSE
NIEKRKGIKLNVFAIANSKKVLLNADGVDQNWKSNVETHGRSYQIQDVIDYAKAHHLENL
IAIDNTASASFVENYITLAENSFDLISSNKVANTLSYDFYVKLRQVLDENQKNYLYETNV
GAGLPLIDTIKLLHLSGENITKIKGVFSGTLSYLFNHFSEKEVPFSTILQEAIDNGYTEP
DPREDLCGNDVGRKLLILARELDLQNEFEEIAIQNLIPDHLRAGSAADFLTKLNEFDAIY
AQIKEAQQPHHVLRYIGELSGDLQNDKGNLEVKLVSVPKDTALGGLKGSDSFFEIYTESY
GDRPIVIQGAGAGSAVTARGVFGDILRLSDKG
NT seq
2439 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtattaaaatttggtgggaaatcgttagccaacggagaaggacttcaaaaagta
gtagctataattgcagataaaatctcacaaaatgaagctattacggtagtagtttcagca
agaggcaatgctacaaacgaactggaacatctattgcaaatagcggctcaaaatggcaat
tacaaaaccctatttgaggattttaaaaattaccaaatagctggttatcaaaacattata
agtgaaaacaatccatataaaatagccatacaagaagaatttgatattttagaaaaatta
tttgaaggggttagcctaattggcgattttagccccaaaattaaagatcaaattctttca
aaaggagaattgcttgcagcaaaattgctcactgccattttattacatcaaggtataaat
gcccaattggcagatgcgagagacttgattaaaacagattccaattttggcgatgcccag
ccattagaaaacttgtccaaaaaaaatgtcattcaatttttcaaagacaatgccgaaaaa
atcaatatcgtaaccggatttattggatcaaattctaataatgatgctaccacattaggt
cgaaacggcagtaattatacagcctcgttgatagctaattttctggatgcaagtgagtta
caaaactacactcacgtagatggcatttataccgccaatccagaattggttttagatgca
aaaaaaatagaccatttatcttttaacgaagccaatgaattggccaattttggagctaca
attttgcatgccaaaaccatcattccattattagaaaaaaacatacccttgcggattttg
aacacattcaattacgaaaataaggggacattaattacatcgaaaacggaaaaagaaggt
atcaaaacactttcggttatagaaaacgtttcattggtaaatttagaaggaagaggattg
cttggcaaagcaggtgtagatgcacgaatatttagagtaatggccgaaaatcaaattagc
gtaagtattatctctcaaggatcatccgagcgaggtataggattggttgtagcatcagac
aaagcatcgacggccatgattgcacttgaaaaagagtttgaaaatgatttttattcaaaa
gatgttaataagatttccgttacagataatgtatccattatatcaataatcggacaagat
ttaagttcatttcataaaccttataccgctttaattaaaaacaaaattatccctattttg
tttaacaacaccgtaacaggaaaaaacgtaagtttagttgtagataaaaaccaattgaat
aaagcattgaatgtgattcatggtgaaatttttggtgtttcaaaaaagattaacattgct
atttttgggcatggattggttggtggtacattgataaaccaaattttagaatcgtcagaa
aacatcgaaaaaaggaaaggtatcaaattgaatgtttttgcgattgccaattctaaaaaa
gtattgctaaatgccgatggtgtagatcaaaactggaaatccaatgtagaaacccatggt
cgatcctatcaaattcaggatgtaattgattatgccaaagcacaccatttagaaaattta
attgcaatagacaataccgcaagtgcctcatttgtagaaaattacataacattggcagaa
aatagttttgatttgatttcttccaataaagtagccaatactttgagttatgatttttat
gtaaaattgagacaagttttagacgaaaatcaaaaaaattatttgtatgaaaccaatgtt
ggtgcaggattacccttgatagacaccatcaaattactacacctttcgggcgaaaacatt
acaaaaataaaaggtgttttttcgggaacattgagttatttgttcaatcatttttctgaa
aaagaagtgccatttagtaccattttgcaagaagccattgacaatggatatacagagccc
gacccaagagaagatttgtgtggcaatgatgttggtcgaaaattattaattttggcacgt
gagttggatttgcaaaatgaatttgaggaaatagccattcagaatttaataccagaccat
ttacgagcaggaagtgccgctgattttttaactaaattaaatgaatttgatgctatttat
gcccaaataaaagaagcccagcagccccatcatgtattaagatacattggcgaattgtct
ggcgatttgcaaaacgacaaaggtaatttagaagtaaaattagtttctgtaccaaaagat
actgcattaggaggattaaaaggttcggattcgttttttgaaatatataccgaatcttat
ggcgacagacccattgtaattcagggagcaggagcaggatcggcagtaacggcaagaggg
gtttttggtgatattttgagattgtcggataaaggataa
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