Firmicutes bacterium ASF500: N510_000445
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Entry
N510_000445 CDS
T10173
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
fbs Firmicutes bacterium ASF500
Pathway
fbs00300
Lysine biosynthesis
fbs00550
Peptidoglycan biosynthesis
fbs01100
Metabolic pathways
fbs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
fbs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
N510_000445 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
N510_000445 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
N510_000445 (murF)
Enzymes [BR:
fbs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
N510_000445 (murF)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
USF25533
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Position
complement(441821..443212)
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AA seq
463 aa
AA seq
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MESITLAQLLEAVGGRLLGDFDDLSAPILRVDTDSRSIHPGSLFIPLTGARFDGHAYIDS
ALEGGAAGCLTAREREGFLPDKFYVKVADTQRALRDLASWYRGRFDIPFVGVTGSVGKTT
AKDMLAAVLGMKYKVLKTEGNRNNTIGLPLTLLELTREHEIAVLEMGMDRPGEIDYLASA
VRPDVGVITNIGDAHIERLGSRENILKAKCEMLPHIQPGGAVVLNGDDALLSTLRGNTPV
PAIFCGQGEGCGCRAQVTGGDGVSHIHCRLITPGMDREVKVPALGEHMIYPALIAAAVGE
RFGLTPDQIEKGIGQFVPTRMRMNILHRGEGITILDDTYNANPQSMRAAVSVLADSQGSR
KVAILGDMLELGPFAPALHTGVGEYLGEVRVDCLVAVGQLAEHIAQGARDAGVPQVIQCQ
DREEAKAALPQVLCPDCTILVKASRGMKLEELTAQLLELTAEG
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggaaagcatcacactggctcagcttctggaggcggtggggggaaggctgttgggggac
tttgacgacctgtccgcgcccatcctccgggtggacaccgacagccggtccatccacccc
ggctccctgttcatccccctcaccggagcgcggttcgacggacacgcctatattgactcc
gccctggagggcggggccgcaggctgtcttaccgcccgggagcgggaggggtttttaccg
gataaattttatgtcaaggtagccgacacccagcgggccctccgggacctggcctcgtgg
taccggggccggtttgacatccccttcgtgggggtgacgggcagtgtaggcaagaccacc
gccaaggatatgctggcggcggttttgggtatgaagtataaggtgctcaaaaccgagggc
aaccgcaacaacaccatcggcctgcccctgaccctgctggagctgacccgggagcacgag
atcgccgtgctggagatggggatggaccggccgggggagattgactatctggccagcgca
gtccggcccgacgtgggggttatcaccaacatcggcgacgcccatattgagcgcctgggc
agccgggagaacattctaaaggccaagtgcgagatgctgccccacatccagcccggcggc
gcggtggtcctcaacggggacgacgccctgctcagcaccctccgggggaacacgcccgtc
ccggccatcttctgcggccagggggaggggtgcggctgccgggcccaggtcaccggcggc
gacggcgtcagccacatccactgccgcctcatcaccccgggcatggaccgggaggtcaag
gtccccgctctgggggagcacatgatctatcccgccctgatcgccgccgcggtgggggag
cggttcggcctcacccccgaccagatcgaaaagggcatcggccagtttgtgcccacccgg
atgcggatgaacatcctccatcgcggggagggcatcaccattctggacgacacctataac
gccaatccccagtccatgcgggcggcggtgagcgtgctggccgacagtcagggcagccgc
aaggtggcgattctgggcgacatgctggaactggggcccttcgcgcccgccctccacacc
ggcgtaggggagtacctgggcgaggtccgggtggactgcctggtggccgtgggccagctg
gcggagcacatcgcccagggcgcccgggacgccggcgttccccaagtgattcaatgtcag
gaccgggaggaggccaaagccgctctgccccaggtcctttgccctgactgtaccatcctg
gtcaaggcctcccggggcatgaagctggaggagctcaccgcccagctgctggagctgacg
gcggaggggtag
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