Felis catus (domestic cat): 100500937
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Entry
100500937 CDS
T02385
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca04010
MAPK signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04066
HIF-1 signaling pathway
fca04068
FoxO signaling pathway
fca04081
Hormone signaling
fca04114
Oocyte meiosis
fca04140
Autophagy - animal
fca04144
Endocytosis
fca04150
mTOR signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04152
AMPK signaling pathway
fca04211
Longevity regulating pathway
fca04213
Longevity regulating pathway - multiple species
fca04510
Focal adhesion
fca04520
Adherens junction
fca04550
Signaling pathways regulating pluripotency of stem cells
fca04730
Long-term depression
fca04913
Ovarian steroidogenesis
fca04914
Progesterone-mediated oocyte maturation
fca05200
Pathways in cancer
fca05202
Transcriptional misregulation in cancer
fca05205
Proteoglycans in cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05218
Melanoma
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100500937 (IGF1R)
04014 Ras signaling pathway
100500937 (IGF1R)
04015 Rap1 signaling pathway
100500937 (IGF1R)
04066 HIF-1 signaling pathway
100500937 (IGF1R)
04068 FoxO signaling pathway
100500937 (IGF1R)
04151 PI3K-Akt signaling pathway
100500937 (IGF1R)
04152 AMPK signaling pathway
100500937 (IGF1R)
04150 mTOR signaling pathway
100500937 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
100500937 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100500937 (IGF1R)
04140 Autophagy - animal
100500937 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
100500937 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100500937 (IGF1R)
04520 Adherens junction
100500937 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
100500937 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100500937 (IGF1R)
04914 Progesterone-mediated oocyte maturation
100500937 (IGF1R)
09156 Nervous system
04730 Long-term depression
100500937 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
100500937 (IGF1R)
04213 Longevity regulating pathway - multiple species
100500937 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100500937 (IGF1R)
05202 Transcriptional misregulation in cancer
100500937 (IGF1R)
05205 Proteoglycans in cancer
100500937 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100500937 (IGF1R)
05214 Glioma
100500937 (IGF1R)
05218 Melanoma
100500937 (IGF1R)
05215 Prostate cancer
100500937 (IGF1R)
05224 Breast cancer
100500937 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100500937 (IGF1R)
01522 Endocrine resistance
100500937 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
100500937 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
fca04090
]
100500937 (IGF1R)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100500937 (IGF1R)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
100500937 (IGF1R)
CD molecules [BR:
fca04090
]
Proteins
100500937 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100500937
NCBI-ProteinID:
XP_023110734
LinkDB
All DBs
Position
B3:complement(17141463..17452267)
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTDSNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWGHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNITVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPEDMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gcggcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgatatccgt
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgctgctgttccgtgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattacccggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccacggtggactggtccctaatc
ctggatgcggtgtctaataactacatcgtgggaaacaagcccccaaaggaatgtggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaatgaa
tacaactaccgctgctggacgaccaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcacggacagcaacgagtgctgtcaccccgagtgcctgggcagctgcagc
gcgccggacaacgacacggcctgcgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgctttgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacgggagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgcgaggaggagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatctg
ctcattaatatccgccgaggcaataacattgcctcggagctggagaacttcatgggactc
atcgaggtggtgacaggctatgtgaagatccgccattcccacgccttggtctccttgtcc
ttcctcaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactctttc
tatgtccttgacaaccagaacttgcagcagctctgggactggggccaccgcaacctgacc
atcaaagctgggaagatgtactttgctttcaaccccaagttgtgcgtctccgaaatttac
cgcatggaggaggtgaccgggactaaggggcgccagagcaaaggggacatcaatacgagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcacttcacctctacgaccacg
tggaagaaccgtatcatcataacctggcaccggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaggcaccttttaaaaacgtcacggagtatgatggc
caggatgcctgtggctccaacagctggaacatggtagacgtggacctccctcccaacaag
gacgtcgagcctggcattttactgcacggactaaagccttggacgcagtatgctgtttac
gtcaaggcagtgaccctcaccatggtggagaatgaccacatccgcggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctttcggca
tcaaactcctcttctcagctcatcgtgaagtggaacccgccgtccctgcccaacggcaac
ctgagttactacatcgtgaggtggcagcggcagccccaggacagctacctttaccgccac
aactactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccattgacgtc
gaggaggtgaccgagaaccccaagaccgaagtgtgtggcggagagaaggggccttgctgt
gcctgccccaaaaccgaggccgagaagcaggcggagaaggaggaggctgagtaccgcaaa
gtcttcgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcacacaagtcaccaacaccaccatgtccagccgaagcaggaacatcacggtggca
gacacctataatatcacagaccccgaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtgatctctaacctccggcctttcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagtcaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ctgattctaatgtatgaaataaaatatggatcacaaatcgaggatcagcgggaatgtgta
tccagacaggagtaccggaagtatggaggcgccaagcttaaccggctcaacccggggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcgtggacggatcccgtg
ttcttctacgtccccgccaaaataacatatgaaaatttcatccacctgatcatcgctctg
cctgttgccgtcctgctgatagtggggggactggttatcatgttgtacgtcttccacaga
aaaagaaataacagcaggctggggaatggagtgctgtatgcttcggtgaacccagagtac
ttcagtgccgcagatgtgtatgtacctgatgagtgggaggttgctcgggagaaaatcacc
atgagccgagagctggggcagggctcgtttgggatggtctacgaaggagttgccaaaggc
gtggttaaagatgagcccgaaaccagggtggccatcaaaacggtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaacgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtcgtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacgcggggcgatctcaaaagttatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggagagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagggaccttgctgcccggaac
tgcatggtggctgaagatttcacggtcaaaatcggagatttcggtatgacgagagatatc
tacgagacagactattaccggaaaggagggaaggggctgctgcctgtgcgctggatgtca
cccgagtccctcaaggatggggtcttcaccactcactctgacgtctggtccttcggggtc
gttctctgggagatcgccacgctggccgagcagccgtaccagggcttgtccaacgagcaa
gtgcttcgcttcgtcatggagggcggccttctggacaagccggacaactgccccgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggaacccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggatctggagccggaggacatg
gagagcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggccccggcgtgctggttctccgagccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
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integrated database retrieval system
