Felis catus (domestic cat): 101081508
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Entry
101081508 CDS
T02385
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00230
Purine metabolism
fca01100
Metabolic pathways
Module
fca_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101081508 (PFAS)
Enzymes [BR:
fca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
101081508 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
101081508
NCBI-ProteinID:
XP_006939833
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All DBs
Position
E1:3015301..3033334
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AA seq
1336 aa
AA seq
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MPSVLHFYVRPSGHERAASGHTRRKLQGKLPELQAVKTELCYNVNWTAESLPSAEEMKKL
TWLFGCPLLPGDVAQESWLRSDSSDLLLEVGPRLNFSTPASTNVVSVCWAAGLGAVDRVE
TTRRYLLSFAKPPSSETKTLALATLHDRMTEQHFPQPIQSFYLQSMSAPLNGQIDILAEG
RRALEKANRELGLALDSWDLDFYTKRFQELKRNPSTVEAFDLAQSNSEHSRHWFFKGQLH
VDGQEMTHSLFEAIMSTQASSNPNNVLKFCDNSSAIQGKEVRFLQPEDPTRPSCFRQQRA
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
NLPWEDPSFQYPENFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPEPGMDVVKVGGPVYRIGVGGGAASSVQVQGDNSSDLD
FGAVQRGDPEMEQKMNRVIRACVEAARGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPVDRDFLSRVSARERCPACFVGTITGDRRMVL
VDDRDCPVGRNGEGDAPSPPTPVDLELDWVLGKMPRKEFFLQRSVPVLRPLALPPGLSVH
QALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHQELVGAA
TALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALA
DACAAMVAVMAALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCPDITATVTPDL
KRPGGRGRLLFVPLSPGQHRLGGTALAQCFSQLGEQPPNLDLPENLVRAFRITQGLLRDR
LLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAPGVDALPALFAEEPGLVLEVRGPDLA
QVLKRYRDAGLHCLELGATGDAGPHALVRVSVNGAVVLEESVRQLRALWEETSFQLDRLQ
AEPRCVAEEEQGLRERTGPTYCLPPGFPKASVPREPGGPTPRVAILREEGSNGDREMADG
FHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPLAGAE
LRRFRKRPDTFSLGVCNGCQLLALLGWVGGSPSEEAEGTGQDSWPARPGLLLRHNLSGRF
ESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEARGLAPLHWADD
DGNPTEQYPLNPNGSPGGVAGVCSLDGRHLALMPHPERAVRLWQWAWQPPPFDTLTTSPW
LQLFINARNWTREGGC
NT seq
4011 nt
NT seq
+upstream
nt +downstream
nt
atgccctcagtccttcacttctatgtccgtccctctggccatgagagggcggcctctgga
cacactcggaggaagctgcaagggaaattgccagagctgcaggctgtcaagaccgagctg
tgctacaacgtgaactggacagcggagtccctcccaagcgccgaggagatgaagaagctc
acgtggctctttggctgccccttgttaccgggtgatgtggcccaggagtcctggctccgt
tctgactccagcgacctactgctggaggttgggcccaggctgaacttctccaccccagcc
tctaccaacgtcgtgtccgtgtgctgggctgcggggctgggggccgtggatcgcgtggag
actacccggcgctacctgctctcgtttgccaagcccccttcctctgagacgaagaccctg
gctctggctaccctgcatgaccggatgacggagcagcacttcccgcagcccatccagagc
ttctaccttcagagcatgtcagcacctctcaacggccagatcgacatcctggcagagggc
cggcgtgccctggaaaaagccaaccgggagctaggcctggccctagactcctgggacctg
gatttctacaccaaacgcttccaggagctaaagcggaaccccagcaccgtggaggccttc
gacctggctcagtccaatagcgagcacagccgacactggttcttcaagggccagctccac
gtggatgggcaggagatgacgcactccctgtttgaggccatcatgagcactcaggcgtcc
tcgaaccccaacaacgtcctcaagttctgtgacaacagcagcgcaatccaagggaaggag
gtccgattcctgcagcccgaggaccccacgcgaccaagctgcttccggcagcagcgggcg
ctgagacatgtcgtcttcacggcggagacccacaacttccccacaggagtagcccccttc
agtggggcgaccacaggcaccgggggccggatccgagatgtccagtgcacgggccgtggc
gcccacgtggtggctgggactgctggctactgctttggaaacctgcacatcccaggttac
aatttgccctgggaggacccaagcttccagtatcctgagaactttgcccgacccctggag
gtcgccattgaggccagtaatggggcttctgattacggcaacaagttcggggagccagtg
ctggccggcttcgcccgctccttgggcctccagctcccggacggccagcggcgtgagtgg
atcaaacccatcatgtttagtgggggcattgggtccatggaggctgagcatgtgagcaag
gagcccccagagccaggcatggacgttgtaaaggttgggggtcccgtctacaggatcgga
gtcgggggtggagccgcctcatctgtgcaggtgcagggagacaattccagtgatctggac
tttggggctgtgcagcggggagacccggagatggaacagaagatgaaccgtgtgatccgg
gcttgcgtggaggccgccagggggaaccccatctgcagcctccacgaccagggtgccggt
ggtaatggcaacgtcctgaaggagctgagtgacccggctggagctgtcatttacaccagc
cgcttccagcttggggacccgaccctgaacgccctggaaatctggggggccgagtaccag
gagtcgaatgctcttctgctgaggcccgtggaccgagacttcctcagtcgtgtcagcgcc
cgggagcgctgcccagcttgctttgtgggcaccattacgggagacaggaggatggtgctg
gtggacgatcgggactgtcccgtcggaagaaatggcgaaggggacgccccctcgcccccg
acccctgtggacctggagctggattgggtgctgggcaagatgcctcggaaggagttcttc
ctgcagcggagtgtccccgtgctgcgtcctctggccttgcccccagggctgagtgtgcac
caggctctggagcgcgtcctgaggctgcctgctgtggccagcaagcgatacctcaccaac
aaggtggaccgctccgtgggcggcctggtggcgcagcagcagtgcgttgggcccctgcag
acccctctggccgacgtggcggttgtggcattgagtcaccaggagctcgtaggggctgcc
acggctctaggagagcagccggtcaaaagcctgctggaccccaaggttgccgcccgactg
gctgtggccgaagccctcaccaacctggtgtttgctctggtcaccgacctccgggacgtg
aagtgcagcgggaactggatgtgggcggccaagctcccgggggagggcgcggctctggcc
gacgcctgcgcggcgatggtggcggtgatggcggccttgggtgtggcggtggacggtggc
aaggactccctcagcatggccgcccgggtcggctctgagaccgtgcgggcccccgggtcg
ctggtcatctcggcctatgctgtctgtccggacatcacagccaccgtgaccccggacctc
aagcgtcccgggggcagaggccggctgctgttcgtgcctctgagccccgggcagcaccgg
ctggggggcacagccctggcccagtgcttctcgcagctgggcgagcagcccccgaacctg
gaccttcccgagaacctggtgcgtgccttccgcatcacacaggggctgctgcgagaccgt
ctcctctgctcaggccacgatgtcagtgacgggggtctcgtcacctgcctgctagagatg
gcctttgctgggaattgtgggatagaggtggacgtgcctgcccctggggtcgatgcgctg
cctgcattgttcgccgaggagccgggcctggtgctggaggtgcgggggcccgacctggcc
caggtgctgaagcgctaccgggacgccggcctgcactgcctggagctgggcgccacaggc
gacgctgggccccacgccctggtgcgagtgtccgtgaacggggctgtggttctggaagag
tctgtgaggcagctgcgagccctctgggaggagacgagtttccagctggaccggctgcag
gccgagccgcgctgtgtggcggaggaagagcaagggctcagggagcggacggggcccact
tactgcctgcccccgggcttccccaaagcttccgtgccccgagagcctggtggtcccact
ccccgggttgccatcttgcgagaggagggcagtaacggagaccgtgagatggcagacggc
ttccacttggccgggttcgaggtgtgggatgtgaccatgcaggacctctgctctggggcg
atcgggctggacacgttccgcggcgtggccttcgtgggcggcttcagctacgcggatgtc
ctgggctctgccaaagggtgggccgctgctgtgaccttccacccgctagccggggctgaa
ctgagacgtttccggaagcggcccgacaccttcagcctgggcgtgtgtaatggctgtcag
ttgctggctctgctgggctgggtgggaggtagccccagcgaggaggcagaggggacgggc
caggactcctggccggcccggccgggcctcctgcttcgccacaacctgtctgggcgcttt
gagtcccgctgggccagcgtgcgggtgggtcctgggccggccctgatgcttcgagggatg
gaaggagctgtgctacccgtgtggagcgctcatggcgaaggttacatggctttttcttct
ccggaactccaagcccagattgaggccaggggcttggctccgctgcactgggccgacgac
gacgggaaccccacggaacagtatcccctgaaccccaacgggtccccagggggcgtggct
ggagtctgctccctggatggccgccacctggccctcatgcctcaccctgagcgggctgtg
cggctttggcagtgggcgtggcagcctcctccctttgacactctgactacctccccctgg
ctccagctcttcatcaacgcccgaaactggacccgggaggggggctgttga
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