KEGG   Felis catus (domestic cat): 101081846
Entry
101081846         CDS       T02385                                 
Symbol
SOCS3
Name
(RefSeq) suppressor of cytokine signaling 3
  KO
K04696  suppressor of cytokine signaling 3
Organism
fca  Felis catus (domestic cat)
Pathway
fca04120  Ubiquitin mediated proteolysis
fca04380  Osteoclast differentiation
fca04630  JAK-STAT signaling pathway
fca04668  TNF signaling pathway
fca04910  Insulin signaling pathway
fca04917  Prolactin signaling pathway
fca04920  Adipocytokine signaling pathway
fca04930  Type II diabetes mellitus
fca04931  Insulin resistance
fca04932  Non-alcoholic fatty liver disease
fca04935  Growth hormone synthesis, secretion and action
fca05160  Hepatitis C
fca05164  Influenza A
fca05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:fca00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101081846 (SOCS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    101081846 (SOCS3)
   04668 TNF signaling pathway
    101081846 (SOCS3)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    101081846 (SOCS3)
   04920 Adipocytokine signaling pathway
    101081846 (SOCS3)
   04917 Prolactin signaling pathway
    101081846 (SOCS3)
   04935 Growth hormone synthesis, secretion and action
    101081846 (SOCS3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101081846 (SOCS3)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    101081846 (SOCS3)
   05164 Influenza A
    101081846 (SOCS3)
   05168 Herpes simplex virus 1 infection
    101081846 (SOCS3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101081846 (SOCS3)
   04932 Non-alcoholic fatty liver disease
    101081846 (SOCS3)
   04931 Insulin resistance
    101081846 (SOCS3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:fca04121]
    101081846 (SOCS3)
Ubiquitin system [BR:fca04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul5 complex
    Target recognizing subunit
     101081846 (SOCS3)
SSDB
Motif
Pfam: SH2 SOCS_box
Other DBs
NCBI-GeneID: 101081846
NCBI-ProteinID: XP_044901235
UniProt: M3WYS7
LinkDB
Position
E1:complement(58056210..58059634)
AA seq 225 aa
MVTHSKFPAAGMSRPLDTSLRLKTFSSKSEYQLVVNAVRKLQESGFYWSAVTGGEANLLL
SAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGSFSLQSDPRSTQPVPRFDCV
LKLVHHYMPPPGAPALPPPPAEPSSEVPEQPPAQPLAGSPPRRAYYIYSGGEKIPLVLSR
PLSSNVATLQHLCRKTVNGHLDSYEKVTQLPGPIREFLDQYDAPL
NT seq 678 nt   +upstreamnt  +downstreamnt
atggtcacccacagcaagtttcccgccgccgggatgagccgccccctggacaccagcctg
cgcctcaagaccttcagttccaagagcgagtaccagctggtggtgaacgcagtgcgcaag
ctgcaggagagcggcttctactggagcgccgtgacgggcggcgaggcgaacctgctgctc
agcgccgagcccgccggcaccttcctcatccgcgacagctcggaccagcgccacttcttc
acgctcagcgtcaagacccagtcggggaccaagaacctgcgcatccagtgcgaggggggc
agcttttcgctgcagagcgacccccggagcacgcagccggtgccccgcttcgactgcgtg
ctcaagctggtgcaccactacatgccgccccccggcgcccccgccttgccccctccaccc
gccgaaccctcctccgaggtgccggagcagccgccggcccagccgctggcggggagtccc
cccaggagagcctattacatctactccgggggcgagaagatccctctggtgttgagccgg
cccctctcctccaacgtggccactctccaacatctctgtcggaagaccgtcaacggccac
ctggactcctatgagaaagtcacccagctgcctgggcccattcgggaattcctggaccag
tacgatgcccctctttaa

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