Felis catus (domestic cat): 101082315
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Entry
101082315 CDS
T02385
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00020
Citrate cycle (TCA cycle)
fca00480
Glutathione metabolism
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01210
2-Oxocarboxylic acid metabolism
fca01230
Biosynthesis of amino acids
fca04146
Peroxisome
fca05230
Central carbon metabolism in cancer
Module
fca_M00009
Citrate cycle (TCA cycle, Krebs cycle)
fca_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101082315 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101082315 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101082315 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101082315 (IDH2)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101082315 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
101082315
NCBI-ProteinID:
XP_023110679
UniProt:
M3X0N0
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All DBs
Position
B3:5713355..5730001
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AA seq
451 aa
AA seq
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MAGYLRVVRSLCRASGSGPAWAPAAPTGPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVVDRAGTFKIVFSPKDGSGAKEWEVFNFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVQTVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKNNLDKALGQ
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atggctggctacctgcgggtcgtacgctcgctctgcagggcctccggctccgggccggcc
tgggcgccggcagccccgacaggccccaacttgcaggagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccggtggtggagatggacggcgatgagatgacccgg
atcatctggcagttcatcaaggagaagctcatcctgccgcacgtggatgtccagctcaag
tatttcgacctggggctcccaaaccgtgaccagaccaacgaccaggtcaccatagactcc
gcactggccacccagaagtacagtgtggctgtgaagtgcgccaccatcacccccgatgag
gcccgtgtggaagaattcaagctgaagaagatgtggaagagtcccaatggaaccatccga
aacatccttggggggaccgtcttccgggaacccatcatctgcaaaaacatcccacgcctc
gtccccggctggaccaagcccatcaccattggcaggcacgcccatggcgaccagtacaag
gccacagactttgtggtcgaccgggccggcacgttcaagatcgtcttctccccgaaggat
ggcagtggcgctaaggagtgggaagtgttcaatttccctgccggcggcgtggggatgggc
atgtacaacacggatgagtccatctcgggttttgcgcacagctgcttccagtacgccatc
cagaagaagtggccgctgtacatgagcaccaagaacaccatcctgaaagcctacgacggg
cgcttcaaggacatcttccaggaaatctttgacaagcactataagaccgacttcgacaag
aataagatctggtacgagcaccggctcattgatgacatggtggcccaggtcctcaagtct
tcaggcggcttcgtgtgggcctgcaagaactatgatggagacgtgcagtcggacatcctg
gcccagggctttggctccctcggcctgatgacgtctgtgctggtctgcccagatgggaag
accatcgaggctgaggccgctcatgggacggtcacccgccattatagggagcaccagaag
ggccggcctaccagcaccaaccccatcgccagcatctttgcctggacgcgtggcctggag
caccgggggaagctggatgggaaccaggacctcatcaggtttgcacagaccctggagaag
gtgtgtgtccagacggtggagagcggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaacgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagaacaacctggacaaggccctgggccagtag
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