Felis catus (domestic cat): 101082969 Help Entry 101082969         CDS       T02385                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism fca  Felis catus (domestic cat) Pathway fca04072   Phospholipase D signaling pathway fca04115   p53 signaling pathway fca04140   Autophagy - animal fca04150   mTOR signaling pathway fca04151   PI3K-Akt signaling pathway fca04152   AMPK signaling pathway fca04211   Longevity regulating pathway fca04218   Cellular senescence fca04714   Thermogenesis fca04910   Insulin signaling pathway fca04919   Thyroid hormone signaling pathway fca05163   Human cytomegalovirus infection fca05165   Human papillomavirus infection fca05168   Herpes simplex virus 1 infection fca05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     101082969 (TSC2)    04151 PI3K-Akt signaling pathway     101082969 (TSC2)    04152 AMPK signaling pathway     101082969 (TSC2)    04150 mTOR signaling pathway     101082969 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     101082969 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     101082969 (TSC2)    04218 Cellular senescence     101082969 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     101082969 (TSC2)    04919 Thyroid hormone signaling pathway     101082969 (TSC2)   09149 Aging    04211 Longevity regulating pathway     101082969 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     101082969 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     101082969 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     101082969 (TSC2)    05163 Human cytomegalovirus infection     101082969 (TSC2)    05165 Human papillomavirus infection     101082969 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:fca01009]     101082969 (TSC2) Protein phosphatases and associated proteins [BR:fca01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      101082969 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP HEAT Cnd1 Motif Other DBs NCBI-GeneID:  101082969 NCBI-ProteinID:  XP_044903475 LinkDB All DBs Position E3:complement(39441202..39476508) Genome browser AA seq 1807 aa AA seqDB search MAKPTSKDSGLKEKFRILFGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRV IGQICEVAKTKKFEEHAVEALWKAVEDMLQPERPPEARHAVLALLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSVTRLIKKYRRELQAVTWDI LLDIIERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSHERYFELVERCADQRPE SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY EEELISSVVISQLSHIPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVMARSLS APPELEERDVVAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYETLVSHLQLHYKH GYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDSTEPERGSEKKAG GPLSPPTGPSGPAPAGPAVRLGSLPYSLLFRVLLQCLKQETDWKVLKLVLGKLPESLRFK VLIFTSPCSVDQLSSALCSMLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKARQREMVYCLEQGLIYRCASQCVVALAVCSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVREFQESSAADAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQGSPELSSDPSAHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG ALDAQATHCPGAQTTPASTSERASAAAQLPAQEKTSLAAYVPLLTQGWAEILVRRPTGNT SWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGSAKPPPP PRSNTVASFSSLYQTSCQGELHRSISWADSAVVLEEGSPSETDLPGEPTELEDFEATLGP ERRCRRPEAYSRSSSSSSQEEKSFAAEEVAAGGLPIGRAVSAEGARPSAGLSFQPAQPLS KSSSSPELQTLQDTLGDPGDKADVGRLSPEAKARSQSGTLDGAGAAWSTPGEESQGRGPA RPEGPLPSGCPRSPGGLRPRGYTISDSAPSRRGKRVERDAFKSRAGASNTEKVPGINPSF VFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAI LSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHI ATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYECN LVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWI ARLRHIKRLRHRVGQIREEAHYSNPSLPLTQTHPPGHAKAPAEPTPTYETGQRKRLISSV DDFTEFV NT seq 5424 nt NT seq  +upstreamnt  +downstreamnt atggccaagccgacaagcaaggattcaggcttgaaggagaagttcaggattctgtttgga ctgggcaccccgcggccaaaccccaggtctgcagagggcaagcagacggagtttatcatc acggcggaaatcctgagagagctgagcgttgaatgtggcctcaacaatcgcatccgggtg atagggcagatctgtgaagttgcaaaaacgaagaagtttgaagagcatgcagtggaagcg ctctggaaggccgtcgaggacatgctacagccagagcggccaccggaggcccggcatgcg gtgctggctctgctgaaggccatcgtgcaggggcagggggaccgcttgggcgttctcagg gccctcttctttaaggtcatcaaggattacccctctaatgaagatctccacgaaagactg gaagttttcaaggccctcacagacaatgggagacacatcacatatttggaagaagaactg gctgggtttgtgctgcagtggatggacatcggcctgtcctcagagttccttctggtgctt gtgaacttggtcaaattcaacagctgttatctggatgaatacatcgcatcaatggtccac atgatctgcctgctgtgtgtccagactgtgtcctccgtggacatagaggtctctctgcag gtgctggacgccgtcgtctgctacaactgtctgccggctgagagcctgcccctgttcatc gtcactctctgtcgtaccgtcaatgtcaaggagctctgtgagccttgctggaagctgatg cgtaatcttctgggcacccacctgggtcacagtgccatctacaacatgtgccgcatcatg gaggacagagcctacatggaagacgccccgctgctgagaggggccgtgttctttgtgggc atggctctctggggggcgcaccgactctactcgctcaagaactccccgacatccgtgctg ccgtcgttttacgaggccatgacctgtccgaacgaggtggtgtcctatgaaatcgtcctg tctgtcaccagactcatcaagaagtaccggagggagctccaggctgtgacgtgggatatc ctgctggacatcatcgaacgtctgctgcagcagctccagagcctggacagcccggagctc agagccatcgtccatgacctgctgaccacagtggaggagctgtgtgaccagaatgagttc cacggctcgcacgagagatacttcgagctcgtcgagagatgtgcagaccagaggccggag tcctccctcctaaacttaataacctacagggctcagtccatccatccggcaaaggacggc tggattcacaacctgcagttactgatggagagattcttccggaatgaatcccgcagtgct gtgcgcatcaaggtgctcgatgtcctgtcctttgtgctgctcatcaacaggcagttctat gaggaggagctgatcagctcggtggtcatctctcagctctcccacatcccggaggacaaa gacccccaagtccggaaactggccacccagttgctggtggacctggccgaaggctgtcac acccaccacttcaacagcctgctggacattgtggagaaggtgatggcccgctccctttcc gcaccccctgagctggaggaaagagatgtggtggcatattcagcctccttagaggatgtg aagactgccgtcttggggctcctggtgatccttcagaccaagctgtacgccttgcctgcc agccacgcggtgcgtgtgtacgagaccctcgtcagccacctgcagctccactacaagcac ggctataccctgcccatcgccagtagcatccggctgcaggcctttgacttcctgctgctg ctgagggcggactccctgcaccgcctcggcctgcccagcaaggacggggctgtgaggttc agcccctactgcgtctgcgactccacggagccagagagaggctctgagaagaaggccggc ggccccctgtcgcctcccaccgggccatccggcccagcacctgccggtcccgctgtgcgg cttggctccctgccctactccctgctcttccgggtcctgctgcagtgcttaaagcaggag acggactggaaggtgctgaagcttgttctcggcaagctgcccgagtccctgcgcttcaag gtcctcatcttcacgtccccgtgcagcgtcgaccagctgtcttccgccctctgctccatg ctttcaggtcccagaacgctggagcggctccgaggcaccccggaaggtttctccaggacc gacctgcacctggctgtggttcctgtgctgacggcgttaatctcttaccataactatttg gacaaagccagacagcgggagatggtgtactgcctggagcaaggcctgatctaccgctgt gccagccagtgcgtggtggccctggccgtgtgcagcgtcgaaatgcccgacatcatcatc aaggcgctgcctgtcttggtcgtgaagctcacacacatttcggccacagccagcatggcc attccactcctcgaattcctgtcaactctggccaggctgcctcacctctacaggaacttt gccgctgagcagtacgcgagtgtgtttgccatctccctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgcctggcccatcacgtcatagccatgtggttcattagatgc cgtctgccttttcggaaggattttgttccttatatcactaagggcctacgctccaatgtc ctcctgtcttttgatgacaccccggagaaggacagcttcagagcgcggagcaccagtctc aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactcc ccacccgtgagagaattccaggagagctctgcagccgacgccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcacgagtgccagcttg gggtctgcggacgagaactcaatggcccaggctgacgacaacttgaaaaatctccacctg gagctcacggagacttgtctggacatgatggccagatacgtgttctccaacttcacggcg gtccccaagaggtcccctgtaggggagtttctcttggctggtggcaggaccaagacctgg ctggttggaaacaagctcgtcactgtgacgacgagcgtggggaccgggacccggtcactg ctgggcttggactcaggagagctgcagggcagcccagagctgagctctgaccccagtgcg cacgtgaggcagacaaaggaggcgcctgccaagttggagtcccaggctgggcagcaggtg tgccgtggggcccgggaccgcgtccgctccatgtctgggggccacggccttcgtgtcggt gccttggacgctcaagccacccactgcccaggcgcacagaccacaccagccagcacgtcc gagagggcctcggctgccgcccagctcccggcgcaggagaagacgagcctggcggcctac gtacccctgctgacccagggctgggcggagatcttggtccggaggcccacggggaacacc agctggctgatgagcctggagaaccccctcagccccttctcctcggacatcaacaacatg cccctgcaggagctgtccaacgccctcatggccgccgagcgcttcaaggagcgtcgtgac acggccctgtacaagtcactttcggtgccggcggccggctccgccaagccccctccgccc ccacgttctaacacagtggcctctttctcctccctgtaccagaccagttgccaaggagag ctgcacaggagcatttcctgggcagactccgcggtggttctggaggagggaagtcccagc gagactgatttgccaggcgagcccactgagctggaggactttgaggccaccctgggccca gagaggcgctgtcggcgccctgaagcctacagtaggtcgtcttccagctccagccaagag gagaagtctttcgccgcagaggaggtggctgccggagggctccccatcgggcgggccgtg tctgccgagggagcccggccctctgcggggctctccttccagcccgcccagcccctcagc aagtctagctcctcgccggagctgcagaccctgcaggatacactcggggaccctggggac aaggccgacgttggccggctgagccccgaggccaaggcccgctcacagtccgggactctg gacggggcaggtgccgcctggtcaaccccaggtgaagagagtcagggccggggccctgcg aggcccgagggtcccttgccttctggctgtccccgttcccccggtggcctgcgtcccaga ggctacaccatttcggattcggccccgtcacgcagaggcaagagggtagagcgggacgcc ttcaagagcagagctggggcctccaatactgagaaggtgccgggcatcaaccccagcttc gtgttcctgcagctctaccactctcctttctttggcgacgagtccaacaagccgatcctt ctgcctaacgagtccttcgagcgctcggtgcagctcctcgaccagatcccatcctacgac acgcacaagatcgcggtcctgtacgtgggagaaggccagagcagcagcgagctcgccatc ctgtccaacgagcacggctcgtaccggtacacagagttcctgacgggcctgggcaagctc atcgagctcaaggactgccagccggataaggtgtacctgggcggtctggacgtgtgcggg gaggacggccagttcacctactgctggcacgatgacatcatgcaggctgtcttccatatc gccaccctgatgcccaccaaggacgtggacaagcaccgctgtgacaagaagcgccatctg ggcaacgactttgtgtccattgtctataatgattccggcgaggacttcaaactgggcacc attaaaggccagttcaacttcgtccacgtgatcatcacccccctggactacgagtgcaac ctggtgtccctgcagtgcaggaaggacatggagggcctcgtggacaccagcgtggccaag atcgtgtctgatcgcaacctgcccttcgtggcccgtcagatggctctgcacgccaacatg gcctcccaggtgcaccatagccgctccaaccccacggatatctacccgtccaagtggatc gccaggctccgtcacatcaagcggctgcgccaccgggtagggcagatccgtgaggaagcc cactactccaaccccagcctgccgctgacgcagacgcaccctccgggccacgccaaggcc ccggccgagcccacgcccacgtacgagacgggccagcggaagcgcctcatctcctctgtg gatgacttcaccgagttcgtgtga

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