Felis catus (domestic cat): 101084148
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Entry
101084148 CDS
T02385
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04140
Autophagy - animal
fca04141
Protein processing in endoplasmic reticulum
fca04210
Apoptosis
fca04932
Non-alcoholic fatty liver disease
fca05010
Alzheimer disease
fca05012
Parkinson disease
fca05014
Amyotrophic lateral sclerosis
fca05016
Huntington disease
fca05017
Spinocerebellar ataxia
fca05022
Pathways of neurodegeneration - multiple diseases
fca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101084148 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101084148 (ERN1)
09143 Cell growth and death
04210 Apoptosis
101084148 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101084148 (ERN1)
05012 Parkinson disease
101084148 (ERN1)
05014 Amyotrophic lateral sclerosis
101084148 (ERN1)
05016 Huntington disease
101084148 (ERN1)
05017 Spinocerebellar ataxia
101084148 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
101084148 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101084148 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101084148 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101084148 (ERN1)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101084148 (ERN1)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: Other
IRE family
101084148 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
101084148
NCBI-ProteinID:
XP_003997136
LinkDB
All DBs
Position
E1:complement(46718504..46802051)
Genome browser
AA seq
973 aa
AA seq
DB search
MCLGCGLSNLSVFICEIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVL
QVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQ
DIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDY
AASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVMH
INVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHE
GVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLI
GHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVEQTSENAPTAVSQEV
EEKFEHAPAKPEAPVDSVLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQKE
LEKIQLLQQQQLPFHPPGDVAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSSGSAS
RAGASPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPE
CFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLE
PITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHS
FSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQAN
ILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQD
VSDRIEKESLDGPIVKQLERGGRAVVKTDWRENITVPLQTDLRKFRTYKGGSVRDLLRAM
RNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPHLLPHTYRAMEPCSHERLFQPYYFHE
PPELRPPVTPDAL
NT seq
2922 nt
NT seq
+upstream
nt +downstream
nt
atgtgccttggatgcgggctctctaacctcagcgtcttcatctgtgagatttttggaagt
cccagcacagtgacacttcccgaaaccttgttgtttgtgtcaaccctggatggaagcttg
catgctgtcagtaagaggacgggctcaatcaaatggactttaaaagaagatccggttctg
caggttccaacgcatgtggaagagcctgccttcctcccagatcccaatgatggcagcctg
tatacacttgggggcaagaataatgaaggcctgacgaaacttccctttaccatcccagag
ctcgtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaagcag
gacatttggtatgttattgatcttctgaccggggagaagcagcagactttgtcatcggcc
tttgcagacagtctctgcccatcaacctctctgctgtatctcgggcgaacagagtacaca
atcaccatgtacgacaccaaaacccgcgagctccggtggaatgccacctacttcgactac
gcggcctcactgccggaggacgacggggactacaagatgtcccactttgtgtccaacggc
gatgggctggtggtgaccgtggacagtgaatctggcgacgtcctgtggatccaaaactac
gcttcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtgatgcac
atcaacgtcgcagtggagacgctgcgctatctgaccttcatgtctggggaggtgggccgc
atcaccaagtggaagtacccgttccccaaggagacggaggccaagagcaagctgacgccc
accctgtatgtcgggaaatactctaccagcctgtatgcctccccctccatggtgcacgag
ggggtcgccgttgtgccccggggcagcacacttcctttgctggaaggcccccagactgac
ggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagacctaaagttt
gaccctgggctcaaagggaagagcaagctcaactacttgaggaactactggcttctgata
ggacaccatgaaacccccctgtctgcgtctaccaagatgttggagagattccccaataat
ctgcccaaacatcgagaaaatgtgattcctgccgattcagagaagaagagctttgaggaa
gttatcaacctggtcgagcagacttcagaaaacgcgcccaccgccgtttcacaggaagtg
gaggagaagttcgagcatgcccccgctaagcccgaggcccccgtggactctgtgctgaag
gacatagccaccatcatcctgagcaccttcctgctcatcggctgggtggccttcatcatc
acctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttccagaaggaa
ctagagaaaatccagctcctgcaacagcagcagctgcccttccatccccctggagacgtg
gctcaggatgcggagctcctggactcgtccggcctgtactcagagagctcgggcaccagc
agccccagcacatcccccagagcctccaaccactcgctccactccagtggctctgcctcc
agggctggtgccagccccttcctggagcaggacgatgaagatgaggaaaccagcatggtg
attgtcgggaagatctcattctgtcccaaggacgtgctgggccacggagctgagggcacg
attgtgtaccggggcatgttcgacaaccgcgacgtggccgtcaagaggatcctccccgag
tgtttcagtttcgcggaccgtgaggtccagctgcttcgggaatcagacgagcaccccaac
gtgattcgttacttctgcacggagagggaccggcagttccagtacattgccatcgagctg
tgtgcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggcctggag
cccatcaccttgctgcagcagaccacctcgggcctggcccatttgcactccctcaacatt
gttcacagagacctgaagccccacaacattctcctgtccatgcccaacgcacatggcagg
atcaaggccatgatctctgactttggcctctgcaagaagctggctgtgggcaggcacagt
ttcagccgccgctcaggagtgcctggcacagaaggctggatcgctccggagatgctgagc
gaggactgtaaggacaatcccacctacacagtggacatcttctctgcgggctgtgtcttt
tactacgtgatatctgagggcagccacccttttggcaagtccctgcagcggcaggccaac
atcctcctgggcgcctacagcctcgactgcttacacccggagaagcacgaagacgtcatt
gcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccctctgcgaag
catgtgctgaagcacccgttcttctggagcctggaaaagcagctccagttcttccaggac
gtgagtgaccgaatagaaaaggaatccctggacggcccgatagtgaagcagctggagcga
ggcgggagagccgtggtgaagacggactggagagagaacatcaccgtccccctgcagaca
gatctgcgtaaattcagaacctataaaggtggctctgtccgcgaccttctccgagccatg
agaaacaagaagcaccactaccgggagctccccgcggaggtgcgggagacgctgggctct
ctccccgacgactttgtgcgctacttcacgtcccgcttcccccacctcctcccccacacc
taccgggccatggagccctgcagccacgagaggctcttccagccttactacttccacgag
cccccagagctccggccccccgtgactccagacgccctttga
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