KEGG   Felis catus (domestic cat): 101085940
Entry
101085940         CDS       T02385                                 
Symbol
ITGAL
Name
(RefSeq) integrin alpha-L isoform X1
  KO
K05718  integrin alpha L
Organism
fca  Felis catus (domestic cat)
Pathway
fca04015  Rap1 signaling pathway
fca04514  Cell adhesion molecules
fca04613  Neutrophil extracellular trap formation
fca04650  Natural killer cell mediated cytotoxicity
fca04670  Leukocyte transendothelial migration
fca04810  Regulation of actin cytoskeleton
fca05144  Malaria
fca05150  Staphylococcus aureus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05169  Epstein-Barr virus infection
fca05323  Rheumatoid arthritis
fca05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101085940 (ITGAL)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    101085940 (ITGAL)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101085940 (ITGAL)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101085940 (ITGAL)
   04650 Natural killer cell mediated cytotoxicity
    101085940 (ITGAL)
   04670 Leukocyte transendothelial migration
    101085940 (ITGAL)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101085940 (ITGAL)
   05169 Epstein-Barr virus infection
    101085940 (ITGAL)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    101085940 (ITGAL)
  09174 Infectious disease: parasitic
   05144 Malaria
    101085940 (ITGAL)
  09163 Immune disease
   05323 Rheumatoid arthritis
    101085940 (ITGAL)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    101085940 (ITGAL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    101085940 (ITGAL)
   04515 Cell adhesion molecules [BR:fca04515]
    101085940 (ITGAL)
   04090 CD molecules [BR:fca04090]
    101085940 (ITGAL)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101085940 (ITGAL)
Cell adhesion molecules [BR:fca04515]
 Integrins
  Integrin alpha subunits
   101085940 (ITGAL)
CD molecules [BR:fca04090]
 Proteins
  101085940 (ITGAL)
SSDB
Motif
Pfam: VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3 HisK_sensor FG-GAP_2
Other DBs
NCBI-GeneID: 101085940
NCBI-ProteinID: XP_006942210
LinkDB
Position
E3:complement(17843594..17886323)
AA seq 1179 aa
MNSCTIVVRLLLSGPLFFAQVSSYNLEVRHVQNFSFPQAGRHFGYRVLQVGDWVVVGAPG
EGNSTGNLYQCQAGTGHCIPVSLHGSNYTSKYLGMTLATDATKGSLLACDPGLSRTCDQN
VYLSGLCYLFDQNLKGPVLQSHPGYQECIKGNVDLVFLFDGSMSLQQDEFQKILDFMKDV
MRKLSNSSYQFAAVQFSTECKTEFGFLDYVRVKNPDALLGKVKHMRLLTNTFHAINYVTK
EVFQQDRGARPDATKVLIIITDGEATDSDQNIDSAKDIIRYIIGIGKHFETKESQETLHK
FASKPAKEFVKILATFEKLKDLFTELQKKIYAIEGTSKQDLTSFNMELSSSGISADLSQG
HGVVGAVGAKDWAGGFLDMDAKLQDDRFVGNEPLTPEARAGYLGYTVTWLPSDKTFTSLL
AVGAPRYQHVGRVLLFQELKGRGHWSQVQKIDGIQIGSYFGGELCGVDMDQDGETELLLI
GAPLFYGEQRGGRVFVYQRKQLEFEVVSELQGDPGYPLGRFGAAITALTDINGDELADVA
VGAPLEGQGAVYIFNGQHGGLSPQPSQRIEGAQLFSGIQWFGRSIHGVKDLGGDGLTDVA
VGAEGQVIILSSRPVVDVLTLMSFSPAEIPVHEVECSYSASNKKKEGVNITVCFQVKPIT
PQFQGHLVATLTYTLQLDGHRTRSRGLFPGGRRELSRNTEVTQDESCTKFWFHFPVCIQD
LISPINVSLNFSLREEEGTPRDQWLQGQDIQPILRPLPHAETKEIPFEKNCGEDKKCEAN
LKLSFSPARSRVLRLTPSASLSVELMLSNLREDAYWVQLNLSFPQGLSFRKVEILEPHSQ
IPVSCEELPQESKLLTRTLSCNVSSPIFKAGTLVAIQVMFHKLLNSSWGDFVELHASVNC
DNEDSDLLEDNSATTSIPVLYPINILTKDQENSTLYVNFTPKGPKIRHAKHIYEVRIQPS
AYDHNVPPLEALVGVPESRSKGPIKHEWTVQILPRGGQHTQDPSVTCHREDPETLPTVAE
PCLPEAKFRCPLTFKQEILVQVIGTMELVEEIKASSMLSLCSSLSISFNSSKHFHLYDDS
ASLAQVIMKVDIVYEKDMLYVYVLSSTGGLLLFLVILGVLYKLGFFKRNLKEKMEATVEA
SNGIPREDSGQPEPKEEGGDPGCLEPLQEEETQDGNDKD
NT seq 3540 nt   +upstreamnt  +downstreamnt
atgaattcctgcaccatcgtagtgagactgctgctgtctgggcctcttttctttgcccag
gtctccagctacaacctggaagtccgccacgtgcaaaacttctcgttcccacaagccggg
aggcattttgggtaccgcgttctgcaggttggagactgggttgtcgtaggagctccaggt
gaggggaacagcactggaaacctctatcagtgccaggcaggcactggccactgcatccca
gtcagcctgcatggttccaactatacctccaagtacttgggaatgaccctggcgacagac
gccacaaagggaagccttttggcctgtgaccctggactgtctcggacatgtgaccagaat
gtttatctgagtggcctgtgttaccttttcgaccagaatctgaagggtcctgtgctgcaa
agtcatcctggttatcaggaatgtataaagggcaacgtagacttggtatttctgtttgat
ggttcaatgagcctgcagcaagatgaatttcagaaaattctggacttcatgaaggatgtg
atgaggaaactcagcaactcttcctatcagtttgctgcggttcagttttccacggaatgc
aaaacagaatttggtttcttggattatgttagggtgaagaaccctgatgctctgctgggc
aaagtaaaacatatgcggctgttgaccaatacctttcatgccatcaactatgtcacgaaa
gaggtgttccagcaagaccggggggcccggccagatgccaccaaagtgcttatcatcatc
actgacggggaagccactgactcagatcagaacattgactcagccaaagacatcatccgc
tacatcattgggatcggaaagcattttgaaaccaaggaaagtcaggaaacgctccacaag
tttgcctcaaaacctgcaaaggagttcgtaaagattctggccacgttcgagaagcttaaa
gatctgttcactgagctgcaaaagaagatctatgccattgagggcacgagcaaacaggac
ctgacatccttcaacatggagctgtcctccagtgggatcagcgctgacctcagccagggt
catggtgtcgtgggggcagtcggagccaaggattgggctgggggctttctagacatggat
gccaaactgcaggatgatagatttgttgggaatgaaccgctgacaccagaagcaagagca
ggatatttaggttacactgtgacctggctgccctccgacaaaacgttcacatcgctgctg
gcggttggagccccccgataccagcatgtggggcgggtgctgctgttccaggagctgaag
ggcagaggacactggagccaggtccagaaaatagacgggatccagattggctcttatttc
ggtggcgagctgtgtggcgttgacatggaccaagacggggagacagagttgctgctgatt
ggagcccccctgttctatggggagcagaggggaggcagggtgtttgtctaccagagaaaa
cagctggagttcgaagtggtctcagaactgcagggggatcctggctaccctctcgggcga
tttggagcagcgatcacggccctgaccgacatcaatggggacgagctggcggacgtggct
gtgggggcccctctggaggggcagggggctgtgtacatcttcaatgggcagcatggtggg
ctgagcccccagccaagccagcggatagaaggggcccagctgttctcaggaattcagtgg
tttggacgctccattcatggggtaaaagaccttggaggagatggcctgacagatgtggct
gtgggagcggaagggcaggtgatcatactcagctcccggcctgtagtagatgtcctcact
ctgatgtccttctccccggctgagatcccagtgcatgaagtggaatgctcctattcagcc
agtaacaagaagaaagaaggagttaacatcacagtctgtttccaggttaagcctattacc
ccccaatttcaagggcacctggttgccaccctcacttacactctgcagctggatggccat
cggaccagaagccgggggctgttcccaggaggtagacgtgaactcagcaggaacacagag
gtcacccaagacgagtcctgcaccaagttctggttccacttcccggtgtgcattcaagac
ctcatctctcccatcaacgtctccctaaatttctctctccgggaagaagaagggacacca
agggatcaatggctgcagggccaggacattcagcccatcctgagacccttaccgcatgca
gagaccaaggagatcccttttgagaagaactgcggggaggacaagaagtgtgaggcgaac
ctgaagctgtccttctcccctgcaagatccagagtcctacgtctgacgccctctgccagc
ctctccgtagagctgatgctgagtaacttgagagaagatgcctactgggtccaactcaac
ctgagcttcccccagggactctccttccgcaaagtagagatactcgagccccacagccag
atacctgtgagctgcgaggagcttcctcaggaatccaagcttctgaccaggaccctctct
tgcaacgtgagctctccgatctttaaagcgggcaccttggttgccatccaggtgatgttc
cacaagctgctgaacagctcctggggggactttgtcgagctgcacgccagtgtgaactgt
gacaatgaggactcagacctcttggaggacaactctgccaccaccagcatcccagtcctg
taccccatcaacatcctcaccaaggaccaggaaaactccacactgtatgtcaacttcacc
cccaagggtcccaagatccgccatgccaaacacatctacgaggtgaggattcagccttct
gcctatgaccacaacgtgccccccctggaggccttggtcggggtaccagagtcacgcagc
aaggggcccatcaaacacgagtggactgtgcagatcctgcccagaggagggcaacacacc
caggatccttctgtgacctgccaccgtgaggatccggagacgctgcccactgtggctgag
ccttgtttgcccgaagccaagttccgctgcccacttacgttcaagcaggagatcctcgtc
caagtgatcgggacaatggagctggtggaggagatcaaggcctcctccatgctcagcctc
tgtagctctctctccatctccttcaacagcagcaagcacttccacctgtatgacgacagt
gcctccctggcccaggtcatcatgaaggtggacatcgtatatgagaaggacatgctctac
gtctacgtgctgagcagcactgggggactattgttgttcctggtgattctcggggtactc
tacaagctcggcttcttcaaacggaatctgaaggagaagatggaggctaccgtagaagct
tccaatggaatccctagagaagactctggacaaccagagcccaaggaagagggtggggat
ccgggctgcctggagcccctccaggaggaggagacccaggatggaaatgacaaagactga

KEGG   Felis catus (domestic cat): 101087258
Entry
101087258         CDS       T02385                                 
Symbol
ITGB2
Name
(RefSeq) integrin beta-2
  KO
K06464  integrin beta 2
Organism
fca  Felis catus (domestic cat)
Pathway
fca04015  Rap1 signaling pathway
fca04145  Phagosome
fca04390  Hippo signaling pathway
fca04514  Cell adhesion molecules
fca04610  Complement and coagulation cascades
fca04613  Neutrophil extracellular trap formation
fca04650  Natural killer cell mediated cytotoxicity
fca04670  Leukocyte transendothelial migration
fca04810  Regulation of actin cytoskeleton
fca05133  Pertussis
fca05134  Legionellosis
fca05140  Leishmaniasis
fca05144  Malaria
fca05146  Amoebiasis
fca05150  Staphylococcus aureus infection
fca05152  Tuberculosis
fca05166  Human T-cell leukemia virus 1 infection
fca05323  Rheumatoid arthritis
fca05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101087258 (ITGB2)
   04390 Hippo signaling pathway
    101087258 (ITGB2)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    101087258 (ITGB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    101087258 (ITGB2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101087258 (ITGB2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    101087258 (ITGB2)
   04613 Neutrophil extracellular trap formation
    101087258 (ITGB2)
   04650 Natural killer cell mediated cytotoxicity
    101087258 (ITGB2)
   04670 Leukocyte transendothelial migration
    101087258 (ITGB2)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101087258 (ITGB2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    101087258 (ITGB2)
   05134 Legionellosis
    101087258 (ITGB2)
   05150 Staphylococcus aureus infection
    101087258 (ITGB2)
   05152 Tuberculosis
    101087258 (ITGB2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101087258 (ITGB2)
   05144 Malaria
    101087258 (ITGB2)
   05140 Leishmaniasis
    101087258 (ITGB2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    101087258 (ITGB2)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    101087258 (ITGB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    101087258 (ITGB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    101087258 (ITGB2)
   04515 Cell adhesion molecules [BR:fca04515]
    101087258 (ITGB2)
   04090 CD molecules [BR:fca04090]
    101087258 (ITGB2)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    101087258 (ITGB2)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101087258 (ITGB2)
Cell adhesion molecules [BR:fca04515]
 Integrins
  Integrin beta subunits
   101087258 (ITGB2)
CD molecules [BR:fca04090]
 Proteins
  101087258 (ITGB2)
SSDB
Motif
Pfam: Integrin_beta Integrin_b_cyt PSI_integrin Integrin_B_tail EGF_2 I-EGF_1
Other DBs
NCBI-GeneID: 101087258
NCBI-ProteinID: XP_011284106
LinkDB
Position
C2:1755806..1781525
AA seq 770 aa
MLPQHFPLLTLVGLLALWSALGQKCTKFKVSNCRDCVESGPGCAWCQKLNFTGLGEPDSV
RCDTREQLLLKGCAADDIIDPRSLAETYYDQEGVQKQLSPQKVTLHLRPGQAAAFNVTFR
RAKGYPIDLYYLMDLSYSMLDDLINVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFV
NTHPEKLKNPCPNKEKECQAPFAFRHVLKLTNNSHQFQTEVGKQLISGNLDAPEGGLDAM
MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFD
YPSVGQLAHKLAESNIQPIFAVTKRMVKTYEKLTEVIPKSAVGELSEDSSNVVQLIKNAY
NKLSSRVFLDHNTVPNTLRVTYDSFCSNGVSQVDQPRGDCDGVQINVPITFQVKVTATEC
IHEQSFVIRALGFTDTVTVHVLPQCECHCRDMSQNRGLCGDRGSMECGICRCDAGYIGKN
CECQTQGRSSQELEGSCRRDNNSLICSGLGDCLCGQCVCHQSDIPNKSIFGRFCECDNVN
CERYDGLVCGGKERGTCSCGKCSCNPGFEGSACQCDRSTRGCLNPDGFECNGRGRCVCNV
CECDTGYQPPLCLECLGCPSPCGRYLLCAQCLKFDPSHSGSNCTSVCGNVGLLNKPPEKG
RTCKERDVDGCWITYTLRQRVGRDSYDIYVDDSRECATGPQVAPIVGGIVAGVVLIGILL
LGIWKALTHVSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
NT seq 2313 nt   +upstreamnt  +downstreamnt
atgctgccccagcacttcccgctcctcaccctggtgggtctgctcgccctctggtccgcc
ctcggccagaagtgtaccaagttcaaggtcagcaactgccgggactgcgtggagtcgggc
cccggctgtgcctggtgccagaagctgaacttcactgggctgggggagccagactccgtt
cgctgcgacacccgggagcagctgctattgaagggatgtgcagctgacgacatcatagac
cccaggagcctggccgagacctactacgaccaggagggcgtccagaagcagctatcccca
cagaaagtgacactccacctgagaccaggtcaggcggctgccttcaacgtgaccttccgg
cgggccaagggctaccccatcgacctgtactacctgatggacctctcctactccatgctg
gacgacctcatcaacgtcaagaagctggggggtgatctgctccgggctctcaacgaaatc
accgagtcgggccgcatcggcttcgggtccttcgtggacaagacggtgctccccttcgtg
aacacgcaccccgagaagctgaagaacccgtgccccaacaaagagaaggagtgccaggcg
ccgttcgccttcaggcacgtgctgaagctcaccaacaactcccaccagttccagaccgag
gtggggaagcagctcatttccggaaacctggacgcccccgagggcggtctggacgccatg
atgcaggtcgccgcttgcccggaggaaatcggctggcgcaatgtcactcggctgctggtg
ttcgccacggacgacggcttccactttgcgggtgacgggaagctgggcgccatcctgacc
cccaatgacggccgctgtcacctagaggacaacatgtacaaaaggagcaatgaatttgac
tacccatcggtgggccagctggctcacaaactggctgaaagtaacatccagcccatcttc
gccgtgaccaagagaatggtgaaaacctatgagaaactcaccgaggtcatccccaagtca
gcggtgggggagctgtcagaggattccagcaacgtggtgcagctcattaagaacgcctac
aataaactctcctccagggtctttctggaccacaacactgtccccaacaccctgagagtc
acctatgactccttctgcagtaatggagtatcacaggtggaccagcccagaggagactgt
gacggagtccagatcaacgtcccgatcaccttccaggtgaaggtcacggccacagagtgc
atccatgagcagtcctttgtcatccgggccctgggcttcacggacacggtgaccgttcac
gtccttccccagtgcgagtgccattgcagggacatgagccagaaccgcggcctctgtggt
gacaggggctccatggagtgcggcatctgcaggtgcgacgccggctacatcgggaagaac
tgtgaatgccagacgcagggccggagcagtcaggagctggagggcagctgccggagggac
aacaactccctcatctgctcggggctgggggactgcctgtgcgggcagtgcgtgtgccac
cagagcgacatccccaacaagagtatcttcgggcgcttctgcgagtgcgacaacgtcaac
tgcgagcgctatgatggcctggtctgcgggggcaaggagcggggcacctgttcctgcggc
aagtgctcctgcaacccgggcttcgagggctccgcgtgccagtgtgacaggtccacccgg
ggctgcctgaaccccgacggctttgagtgcaacgggcgcggccgctgtgtctgcaacgtg
tgtgagtgtgacaccggctaccagccgcccctgtgcctggagtgcctgggctgcccgtcg
ccctgcggccgctacttgttgtgcgcccagtgcctgaaatttgacccgagccactcgggg
agtaactgtacctcggtgtgcgggaacgtgggcctgctgaacaagcccccggagaagggg
cgcacgtgcaaggagcgggacgtggacggctgctggatcacctacacgctgcggcagcgg
gttggcagggacagctatgacatttacgtggatgacagccgagagtgtgcgacgggcccc
caagttgcccccatcgtggggggcatcgtggcgggggtcgtactcatcggcatcctcctg
ctgggcatctggaaggctctgacccacgtgagtgacctcagggagtacaggcgatttgag
aaggagaagctcaagtcccagtggaacaatgacaacccccttttcaagagcgccaccacg
acagtcatgaacccaaagtttgctgagagttaa

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