Felis catus (domestic cat): 101086266
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Entry
101086266 CDS
T02385
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00260
Glycine, serine and threonine metabolism
fca00630
Glyoxylate and dicarboxylate metabolism
fca00670
One carbon pool by folate
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01230
Biosynthesis of amino acids
fca01240
Biosynthesis of cofactors
fca01523
Antifolate resistance
fca04981
Folate transport and metabolism
Module
fca_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101086266 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101086266 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101086266 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101086266 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101086266 (SHMT1)
Enzymes [BR:
fca01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101086266 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
101086266
NCBI-ProteinID:
XP_003996415
UniProt:
M3WMK4
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Position
E1:11158908..11185413
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AA seq
484 aa
AA seq
DB search
MTAQVNGAHKDADLWSSHEKMLAQPLKDCDTEVYDIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYGLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRRIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKETLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRMYQRQVVANCRALAETLMELGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGFLEKEFQK
VAQFIHRGIELTLQIQDDVGARATLKEFKEKLAGDEKHQRAIRALREEVESFAALFPLPG
LPAF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgacagctcaagtcaacggggctcacaaggatgctgacctgtggtcctcgcatgagaag
atgctggcacagcccctcaaagactgcgacaccgaggtttacgacatcatcaagaaggag
agtaaccggcagagggttgggctggagctgatcgcctcagagaatttcgccagccgggca
gttctggaggctctgggctcttgcttaaataacaagtactctgaagggtacccagggcag
aggtattatggcgggaccgagttcatcgatgagctggagatcctctgtcagaagcgggcg
ctacaggtctatggtctggacccccaatgctggggggtcaatgtccagccctactcaggc
tccccggcaaacttcgccgtgtataccgcgctggtggaaccccacgggcgcatcatgggc
ctggacctgcccgacgggggccacctgacccacgggttcatgacagacaagaagaaaatc
tctgctacgtccatcttttttgaatctatgccctataaggtgaacccggacactggctac
atcaactatgaccaactggaggaaaatgcccgcctcttccacccgaagctgattattgca
gggaccagctgctactcccgaaacctggattatgctcgactgaggaggatcgcagacgac
aacggggcctatctcatggccgacatggcgcacatcagcgggctggtggctgccggcgtg
gtgccttccccctttgagcactgccacgtggtgtccaccaccacccacaaaaccctgcga
ggctgccgcgccggcatgatcttctacaggagaggagtgcgcagcgtggatcccaagacc
ggcaaagagacactgtacaacctggagtcgctcatcaactctgccgtgttcccgggcctg
cagggaggtccccacaaccacgccattgctggggtcgccgtggccctgaaacaagccatg
actccggaattccggatgtaccagcgccaggtggtggccaactgcagggctctggctgag
accttgatggagctgggctacaaagtggtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacggatggtggcagggccgagaaggtactagaagcctgc
tctatagcctgcaacaagaacacctgtccaggtgacaaaagcgcactgcggcccagcgga
ctgcgtctggggactccggcactgacgtcccgaggatttttggaaaaagagttccaaaaa
gtggcccagtttattcacagagggatagaactgactctgcagattcaggacgacgttggt
gccagagccaccctgaaggagttcaaggagaaactggccggggacgagaagcaccaaagg
gccatcagggctctcagggaggaagtggagagcttcgcggctctcttccctctgcccggc
ctgcctgccttttag
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