Felis catus (domestic cat): 101086898
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Entry
101086898 CDS
T02385
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00140
Steroid hormone biosynthesis
fca01100
Metabolic pathways
fca05215
Prostate cancer
Module
fca_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
101086898 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
101086898 (SRD5A2)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
101086898 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
101086898
NCBI-ProteinID:
XP_006930441
UniProt:
M3WDH3
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Position
A3:114711714..114749308
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AA seq
254 aa
AA seq
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MRVPCQQSPVLAGSAALAALGALVLYLAEPSGYGKYSERAMPAAARLPARAAWFLQELPS
FAVPAGILARQPRALFGPPATVLLGLFCGHYFYRTFVYSLRTRGRPFPVVFLVKGFVFCM
GNGLLQGYYLIYCAEYPADWYTDIRFSLGVFLFILGMGINIHSDCILRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSFCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcgggttccctgccagcagagcccggtgctggcgggcagcgccgccctggccgccctg
ggggctttggtcctgtacctggcggagccctccggctacgggaagtactcggagcgcgca
atgcccgccgctgctcgcctgccagcccgcgcagcctggttcctgcaggagttgccatcc
ttcgccgtgcctgcggggatcctcgcccggcagccgcgtgctctcttcggccctccggcc
accgtgcttctgggcctcttctgcggacattacttctacaggacatttgtttactcattg
cgtactagagggaggccttttccagttgtgttcctcgtcaaaggctttgttttctgcatg
ggaaatggacttctccaaggctactatctgatttactgtgctgaataccctgctgattgg
tacacagacatacggtttagcctgggtgtcttcttatttattttgggaatggggatcaac
attcatagcgactgtatactgcgccagctcaggaagcctggagaagtcatctataggatt
ccacaaggtggcttgtttacctacgtttctggagccaatttccttggtgagatcattgaa
tggatcggctatgccctggccacgtggtcgctcccagcgcttgcatttgcctttttctca
ttttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagccctcattccattcatcttttaa
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