Felis catus (domestic cat): 101087186
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Entry
101087186 CDS
T02385
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00280
Valine, leucine and isoleucine degradation
fca00640
Propanoate metabolism
fca00785
Lipoic acid metabolism
fca01100
Metabolic pathways
fca01210
2-Oxocarboxylic acid metabolism
Module
fca_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
101087186 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
101087186 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
101087186 (BCKDHA)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
101087186 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
101087186
NCBI-ProteinID:
XP_003997819
UniProt:
M3W423
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Position
E2:complement(13482442..13501242)
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AA seq
446 aa
AA seq
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MAVAAAAAKLRGSGRGLGQAGVLLLRRLGARGLARYHPQRQEQQHFPSLDDKPQFPGASA
EFVDKLEFIQPNVISGIPVYRVMDRQGQIVNPSEDPHLPQETVLKFYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDSTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNASDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPVIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLQGRGWWDDEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPAQ
LRKQQESLARHLQAYGEHYPLDHFEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtggcggctgctgcggcgaagctccggggctcaggtcgaggcttgggccaggct
ggcgtcctgctcctgcggcggcttggtgctcgggggctggctagatatcacccccagagg
caggagcagcagcactttccatccctggatgacaagccccagttccccggggcctcggcg
gagtttgtagacaagctagaattcatccagcccaatgtcatctctgggatccccgtctat
cgcgtcatggaccggcagggccagatcgtcaaccccagcgaggatccccacctgccccag
gagacggtgctcaagttctacaagagcatgactctgctcaacaccatggaccgcatcctc
tacgagtcccagcggcagggccggatctccttctacatgaccaactatggcgaggagggg
acacatgtggggagtgcggcagcgctggacagcacggacctggtgtttggccagtaccgg
gaggcaggtgtgctaatgtaccgggactaccccctggagctgttcatggcccagtgctat
ggcaacgcgagcgacctgggcaaggggcgccagatgcccgtgcactatggctgcaaggag
cgccacttcgtcaccatctcctctccgctggccacgcagatcccgcaggcggtgggggcg
gcctatgcggccaagcgtgccaacgccaacagagtggtcatctgttacttcggggagggg
gcggccagcgagggggatgcccacgccggcttcaacttcgccgccaccctcgagtgcccg
gtcatcttcttctgccggaacaacggctatgccatctccacgcccacctctgagcagtac
cgcggggacggcatcgctgctcgaggcccgggctacggcatcatgtccatccgcgtggac
ggcaacgatgtgtttgccgtgtacaacgccaccaaggaggcccggcggcgggccgtggct
gagaaccagcccttcctcattgaggccatgacctacaggatcgggcaccacagcaccagt
gacgacagctcggcctaccgctcggtggacgaggtcaattactgggacaagcaggaccac
cccatctcccggctgcggcactacctgcagggccgaggctggtgggacgacgagcaggag
aaggcctggagaaagcagtcccgcaagaaggtgatggaggcctttgagcaggcggagcgg
aagccgaagcccaaccccaacctgctcttctctgacgtgtaccaggagatgccggcccag
cttcgcaagcagcaggagtccctggcccggcacctccaggcctacggcgagcactacccc
ctggaccacttcgagaagtga
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