Felis catus (domestic cat): 101087610
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Entry
101087610 CDS
T02385
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00760
Nicotinate and nicotinamide metabolism
fca01100
Metabolic pathways
fca04068
FoxO signaling pathway
fca04148
Efferocytosis
fca04152
AMPK signaling pathway
fca04211
Longevity regulating pathway
fca04213
Longevity regulating pathway - multiple species
fca04218
Cellular senescence
fca04310
Wnt signaling pathway
fca04922
Glucagon signaling pathway
fca04936
Alcoholic liver disease
fca05031
Amphetamine addiction
fca05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
101087610 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
101087610 (SIRT1)
04068 FoxO signaling pathway
101087610 (SIRT1)
04152 AMPK signaling pathway
101087610 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101087610 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
101087610 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
101087610 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
101087610 (SIRT1)
04213 Longevity regulating pathway - multiple species
101087610 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101087610 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
101087610 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101087610 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
fca03036
]
101087610 (SIRT1)
03029 Mitochondrial biogenesis [BR:
fca03029
]
101087610 (SIRT1)
Enzymes [BR:
fca01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
101087610 (SIRT1)
Chromosome and associated proteins [BR:
fca03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
101087610 (SIRT1)
Mitochondrial biogenesis [BR:
fca03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
101087610 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
101087610
NCBI-ProteinID:
NP_001277175
UniProt:
U3U720
LinkDB
All DBs
Position
D2:29077321..29142485
Genome browser
AA seq
746 aa
AA seq
DB search
MADEAALALQPGGSPSAVVAEREAASPPAGEPLRKRPRRDCPGLGRSPGEPGGAAPEREV
PAATGGCPAAAAALWREAAAAGEEREAQAATAGEGDNGPGLQGLTREPPPADDFYDDDDD
DDDEGEEEEEAAAAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIG
PYTFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTI
EDAVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYFR
KDPRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCH
GSFATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFH
RAMKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCD
VIINELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEDSSSPER
TSPPDSSVIVTLLDQATKSNVNDPEVSEPRDHMEEKSQEGQNSTRNIESVTEQLGSPDSK
NVDSNTGEKNERTSIAETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDS
EDDVLSSSSCGSNSDSGTCQSPSLEEHLEDESEIEEFYNGLEDDADVNERAGGTGFGVDG
GDQEAVNEAISVKQEATDINYPSNKS
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcggcggtggtggcc
gagagggaggccgcgtcgccgcccgccggagagccactccgcaagaggccgcggagagac
tgtccaggcctggggcggagcccgggcgagcccggtggggcggcccccgagcgtgaagtg
ccggcggcgaccggaggctgccccgcggcggccgcggcgctgtggcgggaggcggcagcg
gcgggcgaggagcgggaggcccaggcggcgacggccggagaaggagacaatgggccgggc
ctacagggcctaacccgggagccgccgccggccgacgacttctacgacgacgacgacgac
gacgacgacgagggcgaagaggaggaagaggcggcggcggcggcggcgattgggtaccga
gataaccttctgtttggtgatgaaataatcaccaatggttttcattcctgtgaaagtgat
gaggatgatagagcctcgcatgcaagttctagtgactggactccaaggccacgtataggt
ccatatacttttgttcagcaacatctcatgattggcacagatcctcgaacaattcttaaa
gatttattaccagaaacaattcctccacctgaattggatgatatgacactgtggcagatt
gttattaatatcctttcagagccaccaaaaaggaaaaaaagaaaagatattaatacaatt
gaagatgctgtgaaattattacaagagtgcaaaaaaataatagttctaactggagctggg
gtttctgtttcttgtggaatacctgacttcaggtcaagagatggtatttatgctcgcctt
gcaatagacttcccagaccttccagaccctcaagcaatgttcgatattgaatatttcaga
aaagatccaagacctttcttcaagtttgcaaaggaaatatatcccggacagttccaacca
tctctctgtcacaaattcatagccttgtcagataaggaaggaaaactgcttcggaactat
actcagaacatagatacactggaacaggttgcaggaatccaaaggataattcagtgtcat
ggttcctttgcaacagcctcttgcttgatttgtaaatacaaagtagactgtgaagctgta
cgaggagatatttttaatcaggtggttcctcgttgtcctaggtgcccagctgatgaacca
cttgctatcatgaagccagagattgtcttttttggtgaaaatttaccagagcagtttcat
agagccatgaagtatgacaaagatgaagttgatctccttattgttattgggtcttccctg
aaagtaagaccagtagcactaattccaagttccataccccatgaagtgcctcagatacta
ataaatagagaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgat
gtcataattaatgaattatgtcataggttaggtggtgaatatgccaaactttgctgcaac
cctgtaaagctttcagaaattactgaaaaacctccacgaacacaaaaagagttggctcat
ttgtcagagttgccacccacacctcttaatatttcagaagactcaagttcaccggaaaga
acttcaccaccagattcttcagtgattgttacacttttagaccaagcaactaagagcaat
gttaatgatcctgaggtgtctgaaccaagagatcatatggaagaaaaatcacaggaagga
cagaattctactaggaacattgaaagtgttactgaacagctgggaagtccagattcgaag
aatgttgactctaatactggggaaaaaaatgaaagaacttcaattgctgaaacagtgagg
aagtgctggccagctcgacttgcaaaggagcagattagcaaacggcttgatggtaatcag
tatctgtttttaccaccaaatcgttatattttccatggcgctgaggtatattcagactct
gaagatgacgtgttatcctctagttcttgtggcagtaacagtgatagtggaacatgccag
agtccaagtttagaagaacacttggaggatgaaagtgagattgaagaattttacaacggt
ttggaagacgatgctgatgttaatgagagagctggaggaactggatttggagttgatgga
ggtgatcaagaggcagttaatgaagctatatccgtgaaacaggaagcaacagacattaac
tatccatcaaacaaatcataa
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