Felis catus (domestic cat): 101087622
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Entry
101087622 CDS
T02385
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04110
Cell cycle
fca04360
Axon guidance
fca04722
Neurotrophin signaling pathway
fca05200
Pathways in cancer
fca05206
MicroRNAs in cancer
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05220
Chronic myeloid leukemia
fca05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101087622 (ABL1)
04014 Ras signaling pathway
101087622 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
101087622 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101087622 (ABL1)
09158 Development and regeneration
04360 Axon guidance
101087622 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101087622 (ABL1)
05206 MicroRNAs in cancer
101087622 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
101087622 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
101087622 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
101087622 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101087622 (ABL1)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101087622 (ABL1)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
ABL family
101087622 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
101087622
NCBI-ProteinID:
XP_003996023
UniProt:
M3W3H7
LinkDB
All DBs
Position
D4:88657609..88808458
Genome browser
AA seq
1150 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAAEHKDPTEVPETPHSKGPGETDPLDHEPPVSPLLPRKERGPQD
GGLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKGAGEEEGRET
SNGAPALTPSDAAEPAKSPKPSSGAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAS
EEESGGSSSKRFLRSCSASCVPHGARDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASENRSDQATRGTVTPPPRLVKKTEEAADEVFRDAGESSPGSSPPSLTPKLLRRQ
VTGAPSSGLPHKDETAKSGALGTPVAAEPVPPASRAGPGASGGTGKAPAEEPRARRHKPS
SESPGRDKGKLSKLKPAPPPPPPASVGKAGKPAQNPTQEAAGEASTGGKTKAAAVVVDAV
NSDAIKPSPLGEGVKKPALPSVPKPQSSGKPAGAPAGAAPAPSTLPSAASALAGDQPAST
AFIPLISTRVSLRKTRQPPERIASGTITKSVVLDGTEALCLAISKNSEQMASHSAVLEAG
KNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSS
VKEISDIVQR
NT seq
3453 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagaggaggccaagcttgcctgccctg
cactttatcaaaggagcagggaagaaggagtcatcgaggcacgggggtccgcactgcaat
gtctttgtggaacacgaagcccttcagaggccagtagcgtctgactttgagccccaaggt
ctgagcgaagcggctcgttggaactccaaggaaaaccttcttgctggtcccagcgaaaat
gaccccaacctttttgttgcactgtatgattttgtggccagtggggataacaccctaagc
atcactaaaggtgaaaagctccgggttttaggctacaaccacaatggggaatggtgtgag
gcccaaaccaaaaatggccaagggtgggtcccgagcaactacatcacgccggtcaacagt
ctggagaaacattcctggtaccacgggcccgtgtcccgcaacgccgccgagtacctgctg
agcagcgggatcaacggcagcttcttggtgcgggagagcgagagcagccccggccagagg
tccatctcgctgagatacgaagggagagtgtaccactacaggatcaacactgcttctgat
ggcaagctctacgtctcctcagagagccgcttcaacactttggcggagttggttcatcat
cactcgactgtggcggacgggctcatcaccactctccattacccggcccccaagcgcaac
aagcccaccgtctacggcgtgtcccccaactacgacaagtgggagatggaacgcacggac
atcaccatgaagcacaagctgggaggcggccagtatggagaggtgtacgagggcgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtggaa
gagttcttgaaagaagccgcagtgatgaaggagatcaagcaccccaacctcgtgcagttg
ctgggggtctgcacccgggagcccccgttctatataatcactgagttcatgacctatggg
aacctgctggattacctgcgggagtgtaaccggcaggaggtgaacgctgtggtgctgctg
tacatggccacgcagatctcgtcagccatggagtacctggagaagaagaacttcatccac
agagatcttgctgcccgaaactgcctggtaggggagaaccacttggtgaaggtggctgat
ttcggcctgagcaggttaatgacaggggatacgtacacagcccacgccggggccaagttc
cccatcaagtggacagcgccagaaagcctggcctacaacaagttctccatcaagtccgac
gtctgggcgtttggagtactgctttgggaaattgctacctacggtatgtcaccttaccca
ggaattgacctgtcccaggtatacgagctgctagagaaagactatcgcatggaacgcccg
gaaggctgcccagagaaggtctacgaactcatgcgagcatgttggcagtggaatccctcc
gaccggccctcctttgctgaaatccaccaagcctttgagaccatgttccaagagtccagc
atatcagatgaagtggaaaaggaactggggaaaaaaggtgtgcgaggggttgcgagtact
ttgctgcaggccccagagctgcccaccaagacgagaacgtccaggagagccgcggagcac
aaagaccccactgaggtgcccgagacgccccactccaagggcccaggagagaccgatcct
ctggaccacgagccccctgtgtctccactgctccctcgaaaagaacgaggtccccaggat
ggcggcctgaatgaggatgagcggcttcttcccaaagacaaaaagaccaacttgttcagt
gccttgatcaagaagaagaagaaaacggccccaacgcccccgaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaagggggccggcgaggaagagggccgagaaacc
agcaacggggcaccggctctcacaccctcggacgcagccgagccagccaagtccccaaag
cccagcagcggggctggcgtccccaacggagccttccgggagtccgggggtgcaggcttc
cggtctccccacctgtggaaaaagtccagtacgctgaccagcagccgcctagcagccagc
gaggaggagagtggcggcagctccagcaagcgcttcctgcggtcctgctcggcctcctgc
gtgccccacggagccagggacaccgagtggaggtctgtcacactgcctcgggacctgcag
tccacgggcaggcagttcgactcgtccacgtttggagggcacaaaagcgagaagccggct
ctgcctcggaagcgggcgagtgagaacaggtccgaccaggcgaccagaggcacggtgact
cccccacccaggctggtgaaaaagaccgaggaagcagccgatgaggtctttcgagacgcg
ggggagtccagcccgggctccagccccccaagtctgactccaaaactcctccgcaggcag
gtcacgggggctccttcctctggccttccccacaaggacgagaccgccaagtccggtgcc
ttggggacacctgtcgcagctgagccggtgccccccgccagcagagcagggccaggtgcg
tccggagggaccggcaaggcccccgccgaggagcccagagcgaggaggcacaagccttcc
tccgagtccccggggagagacaaggggaaactgtccaagctcaaacctgccccaccgccc
ccgccgccggcctccgtggggaaagccgggaagcccgctcagaacccgacccaggaagcg
gccggggaggccagcactggcgggaaaacgaaagccgcggctgtggtcgtggatgctgtg
aacagtgacgccatcaagcccagtccgctgggagagggcgtcaaaaagcccgcgctccca
tccgtgccaaagccgcagtcgtccggcaagccagcgggggccccagccggggcggcgccc
gccccctccacgctgccatcagcagcctccgccctggccggggaccagcccgcgtctact
gccttcatccctctcatatcgacccgcgtgtctcttcggaaaacccgccagcctccggag
cggatcgccagcggcaccatcaccaagagcgtggtcctggacggcaccgaggccctgtgc
ctggccatctccaagaactccgagcagatggccagccatagcgccgtgctggaagccggc
aaaaacctgtacacgttctgcgtgagctatgtggattccatccagcagatgaggaacaaa
ttcgccttccgcgaggccatcaacaaactggagaataatctccgggagcttcagatctgc
ccggcgacagcagggagtggcccggcggccactcaggacttcagcaaactcctcagctcc
gtgaaggagatcagtgacatcgtacagaggtag
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