Felis catus (domestic cat): 101088847
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Entry
101088847 CDS
T02385
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04062
Chemokine signaling pathway
fca04068
FoxO signaling pathway
fca04072
Phospholipase D signaling pathway
fca04150
mTOR signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04510
Focal adhesion
fca04540
Gap junction
fca04630
JAK-STAT signaling pathway
fca04650
Natural killer cell mediated cytotoxicity
fca04660
T cell receptor signaling pathway
fca04662
B cell receptor signaling pathway
fca04664
Fc epsilon RI signaling pathway
fca04714
Thermogenesis
fca04722
Neurotrophin signaling pathway
fca04810
Regulation of actin cytoskeleton
fca04910
Insulin signaling pathway
fca04912
GnRH signaling pathway
fca04915
Estrogen signaling pathway
fca04917
Prolactin signaling pathway
fca04926
Relaxin signaling pathway
fca04935
Growth hormone synthesis, secretion and action
fca05034
Alcoholism
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05163
Human cytomegalovirus infection
fca05165
Human papillomavirus infection
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05206
MicroRNAs in cancer
fca05207
Chemical carcinogenesis - receptor activation
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05210
Colorectal cancer
fca05211
Renal cell carcinoma
fca05213
Endometrial cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05220
Chronic myeloid leukemia
fca05221
Acute myeloid leukemia
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
fca05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101088847 (SOS2)
04012 ErbB signaling pathway
101088847 (SOS2)
04014 Ras signaling pathway
101088847 (SOS2)
04630 JAK-STAT signaling pathway
101088847 (SOS2)
04068 FoxO signaling pathway
101088847 (SOS2)
04072 Phospholipase D signaling pathway
101088847 (SOS2)
04151 PI3K-Akt signaling pathway
101088847 (SOS2)
04150 mTOR signaling pathway
101088847 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101088847 (SOS2)
04540 Gap junction
101088847 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101088847 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101088847 (SOS2)
04660 T cell receptor signaling pathway
101088847 (SOS2)
04662 B cell receptor signaling pathway
101088847 (SOS2)
04664 Fc epsilon RI signaling pathway
101088847 (SOS2)
04062 Chemokine signaling pathway
101088847 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
101088847 (SOS2)
04912 GnRH signaling pathway
101088847 (SOS2)
04915 Estrogen signaling pathway
101088847 (SOS2)
04917 Prolactin signaling pathway
101088847 (SOS2)
04926 Relaxin signaling pathway
101088847 (SOS2)
04935 Growth hormone synthesis, secretion and action
101088847 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101088847 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
101088847 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101088847 (SOS2)
05206 MicroRNAs in cancer
101088847 (SOS2)
05205 Proteoglycans in cancer
101088847 (SOS2)
05207 Chemical carcinogenesis - receptor activation
101088847 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
101088847 (SOS2)
05231 Choline metabolism in cancer
101088847 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
101088847 (SOS2)
05225 Hepatocellular carcinoma
101088847 (SOS2)
05226 Gastric cancer
101088847 (SOS2)
05214 Glioma
101088847 (SOS2)
05221 Acute myeloid leukemia
101088847 (SOS2)
05220 Chronic myeloid leukemia
101088847 (SOS2)
05211 Renal cell carcinoma
101088847 (SOS2)
05215 Prostate cancer
101088847 (SOS2)
05213 Endometrial cancer
101088847 (SOS2)
05224 Breast cancer
101088847 (SOS2)
05223 Non-small cell lung cancer
101088847 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
101088847 (SOS2)
05160 Hepatitis C
101088847 (SOS2)
05163 Human cytomegalovirus infection
101088847 (SOS2)
05165 Human papillomavirus infection
101088847 (SOS2)
09165 Substance dependence
05034 Alcoholism
101088847 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101088847 (SOS2)
01522 Endocrine resistance
101088847 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
PH_10
IQ_SEC7_PH
PH_13
Motif
Other DBs
NCBI-GeneID:
101088847
NCBI-ProteinID:
XP_023111443
Ensembl:
ENSFCAG00000031655
UniProt:
M3XDB9
LinkDB
All DBs
Position
B3:complement(97748178..97838609)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPCDI
ERIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPICPFYNRHLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFEIVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYKISFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLN
EEPLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGPL
HSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPEWLRDVSTCPNSPN
TPPSTPSPRVPRRCYALSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPSY
RLPLLENAETPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactgctggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctcagct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcagccaaggactgttcaagatgtggaggaacgtgttcagaagacctttcctcat
ccaattgacaagtgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactgcctgtggacaaaatccatccttcattgaaggaggttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgatcaggatgac
ataggtttggtttctctctgtgaagatgaaccaagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcagtatctacgggaattaaatatgatt
ataaaagtgtttcgagaagctttcctttctgacaggaagctatttaaaccttgtgatatt
gaaaggattttcagtaacatttcagatatacatgaattgaccgtgaaacttctaggtctt
attgaagacacagttgaaatgactgatgaaagcagccctcatccattagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacattatcacaggatatt
ctgtctccaaaatttaatgaacatttcagtaagttgatggccagacctgcagtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgcctgtatatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctatttgccctttttataatcgtcacttaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaattcattatggaaggtccattgacacgaattggtgctaaacatgaacggcatattttt
ctctttgatggcttaatgattagctgtaagcccaatcatagccagtcacgccttccaggt
tacagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacctgtgagtgtaaacatgcttttgaaatagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagagaaaaataattggatggccgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcagccactgagattaccaagtcctgaagtgtatcgttttgtggtaaaagactct
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaattcccatcattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgtccgtacttttcttactacataccgttcattttgtaaaccacaggaattactaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggca
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggatcttaaatgtgtttcggcactgggttgaacatcatttttat
gactttgaaagagatttggagttgcttgagagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaagtgggtagagtcaattgctaagatcatcaagaggaagaaacaa
gctcaggcaaatggaataagccataatattacctttgagagtccacctccaccaattgaa
tggcatattagcagaccaggacagtttgaaacatttgatcttatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtccagccttct
gaacttgtagggagtgtgtggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctctggtttgaaaagtgcattgtggaagca
gaaaattttgaggaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcaatggtgtattggagatagtcagtgcagtaaattcagtgtca
gtgtacagactagaccatacttttgaggcattgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaagtgcttctgaa
aaggagtttacagattatttgttcaataagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaaatcaactttctctttaaaatctcctggaataaggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacaccattagaa
agagaaccatataagataagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacgccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacagttcctgtggcagcaatagcatctttgctcca
gtcctcttgccacattcaaagtctttcttcagttcatgtggtagtttacataaactaaat
gaagagccactgattcctcctccacttcctcctcgaaaaaagtttgatcatgatgcttca
aattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacaacct
cctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgacgggcctctg
catagtccacctccaccaccgccgagagatcctcttcctgatacccctccaccagttccc
cttcggcctccagaacactttataaactgtccatttaatcttcagccacctccactagga
catcttcacagagatccagagtggctcagagacgttagtacctgtccaaattcaccaaat
actcctcctagcacaccctctccaagagtaccacgtcgatgctatgcgctcagttccagt
cacaataaccttgctcatcctcaagctccccctgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttataaacgggagctttcacaccccccatcgtac
agactgcctttgctagaaaatgcagaaactcctcaatga
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integrated database retrieval system
