Felis catus (domestic cat): 101088959
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Entry
101088959 CDS
T02385
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X3
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca04062
Chemokine signaling pathway
fca04081
Hormone signaling
fca04148
Efferocytosis
fca04151
PI3K-Akt signaling pathway
fca04217
Necroptosis
fca04550
Signaling pathways regulating pluripotency of stem cells
fca04630
JAK-STAT signaling pathway
fca04658
Th1 and Th2 cell differentiation
fca04659
Th17 cell differentiation
fca04725
Cholinergic synapse
fca04917
Prolactin signaling pathway
fca04920
Adipocytokine signaling pathway
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca04935
Growth hormone synthesis, secretion and action
fca05140
Leishmaniasis
fca05145
Toxoplasmosis
fca05152
Tuberculosis
fca05161
Hepatitis B
fca05164
Influenza A
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05168
Herpes simplex virus 1 infection
fca05200
Pathways in cancer
fca05207
Chemical carcinogenesis - receptor activation
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101088959 (JAK2)
04151 PI3K-Akt signaling pathway
101088959 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
101088959 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101088959 (JAK2)
09143 Cell growth and death
04217 Necroptosis
101088959 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
101088959 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
101088959 (JAK2)
04659 Th17 cell differentiation
101088959 (JAK2)
04062 Chemokine signaling pathway
101088959 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
101088959 (JAK2)
04917 Prolactin signaling pathway
101088959 (JAK2)
04935 Growth hormone synthesis, secretion and action
101088959 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
101088959 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101088959 (JAK2)
05207 Chemical carcinogenesis - receptor activation
101088959 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101088959 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
101088959 (JAK2)
05164 Influenza A
101088959 (JAK2)
05168 Herpes simplex virus 1 infection
101088959 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101088959 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
101088959 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101088959 (JAK2)
05140 Leishmaniasis
101088959 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101088959 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101088959 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101088959 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101088959 (JAK2)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101088959 (JAK2)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101088959 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
FERM_M
Motif
Other DBs
NCBI-GeneID:
101088959
NCBI-ProteinID:
XP_019671273
UniProt:
A0A337SI69
LinkDB
All DBs
Position
D4:complement(6556174..6674815)
Genome browser
AA seq
1022 aa
AA seq
DB search
MGMACLTMTEMEGVSVSPVHQNGDIPGNANSVKQIDPLLQVYLYHSLEKADGEYLKFPTG
EYVAEEICVAASKACGITPVYHSMFALMSETERTWYPPNHVFHVDESTRHNVLYRIRFYF
PYWYCNGSNRTYRHGVSRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKIPVTHETQEECLG
MAVLDMMRLAKEKDQTPLDIYSSISYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIVITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVTIKQGNQEGSNESRIVTIHKQDGKNLEIELSSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPILMDFAISKLKKAGNQT
GLYVLRCSPKDFNKYFLTFAVERDNVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKLKDKSNLLVFRTNGVSDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSISILWKLEVAKQLAWA
MHFLEEKALIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNRIGTLGFSGAFEDRDP
TQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEI
LKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQIC
KGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWM
RN
NT seq
3069 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcttgccttaccatgacggaaatggaaggagtatctgtatctcctgtgcat
cagaatggtgatattcctggaaatgctaattctgtgaagcaaatagatccactccttcag
gtgtatctttatcattctcttgagaaggctgatggagaatatctgaagtttccaactggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcttgtggaatcacgcccgtg
tatcatagtatgtttgctttaatgagtgaaaccgaaaggacctggtatccgcccaaccat
gtcttccatgtagatgaatcaaccaggcacaacgtactctacagaataagattttacttt
ccttactggtattgtaatggcagcaacagaacctatcggcatggagtgtctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat
tttttacatggatggataaaaataccggtgactcatgaaacgcaggaagaatgtcttgga
atggcagtgttagatatgatgagactagccaaagagaaggatcaaaccccattggacatc
tatagctctatcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaagagaataaggtatagatttcgcagatttattgagcagttc
agccactgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaca
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattgtaataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgacttt
cctgatatcattgatgtgactattaaacaaggaaaccaagaaggctcaaatgaaagtaga
attgtaactatccataagcaagatggtaaaaatctggaaattgaactaagctcattaaga
gaagctttatcctttgtgtcattaattgatggctattacagattaaccgcggatgcacat
cattacctctgtaaagaagtagctcctccgatggtgcttgaaaatatacaaagcaactgt
catggcccgattttaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gtcgagcgagataatgtcatcgaatataagcattgtttgattacaaaaaatgagaatgga
gaatacaacctcagtgggaccaagaagaacttcagtaatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgcccc
ccaaagttgaaagataaatcaaatcttctagtctttagaaccaatggcgtttctgatgta
ccaacatcaccaacattacagaggcataataatgtgaaccaaatggtgtttcacaaaatc
agaaatgaagatttaatatttaatgaaagccttgggcaaggcacttttacaaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacacagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaagcacctggttttaaattatggagtatgtgtctgtggagag
gaaaatattctggttcaggagtttgtaaaatttggatcattagatacatacctgaaaaag
aataaaaattctataagtatattatggaaacttgaagtggctaaacagttggcatgggcc
atgcattttctagaagaaaaagcccttattcatgggaatgtgtgtgccaaaaatattctg
cttatcagagaagaagacagaaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattcttcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagacaagcctctgagtgctttggattctcaa
agaaagctccagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataactgtatggattatgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattacgagctattaacagaaaatgac
atgttgccaaataggataggcacccttgggttttctggagcttttgaagaccgagacccg
acacagtttgaagagagacacttgaaatttctacagcagcttggcaagggcaattttggc
agtgtggagatgtgccggtatgaccctctacaagacaacactggggaggtggtggccgtg
aagaagctccagcacagtactgaggagcacctgagagactttgaaagagaaattgaaatc
cttaaatccctgcagcatgacaacattgtcaagtacaagggagtgtgctacagtgctggc
cggcgtaatttaagattaattatggaatatttaccatatggaagtttacgagattatctc
caaaaacataaagaacggatagatcataaaaaacttctgcagtatacatctcagatatgc
aagggcatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaaggaat
atattggtggagaatgaaaacagggttaaaattggagattttggtttaaccaaagtcttg
ccacaagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggatg
agaaattaa
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