KEGG   Felis catus (domestic cat): 101090019
Entry
101090019         CDS       T02385                                 
Symbol
HERC1
Name
(RefSeq) probable E3 ubiquitin-protein ligase HERC1 isoform X1
  KO
K10594  E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101090019 (HERC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:fca04121]
    101090019 (HERC1)
Enzymes [BR:fca01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     101090019 (HERC1)
Ubiquitin system [BR:fca04121]
 Ubiquitin ligases (E3)
  HECT type E3
   101090019 (HERC1)
SSDB
Motif
Pfam: RCC1 RCC1_2 HECT SPRY WD40_CDC20-Fz WD40 WD40_WDHD1_1st WD40_Prp19 Beta-prop_CAF1B_HIR1 Beta-prop_EML_2 Beta-prop_IFT140_1st Beta-prop_WDR35_TULP_N Beta-prop_TEP1_2nd Beta-prop_RIG_2nd WDR55 Beta-prop_WDR75_1st WD40_MABP1-WDR62_2nd Beta-prop_EML CLASP_N Na_trans_assoc
Other DBs
NCBI-GeneID: 101090019
NCBI-ProteinID: XP_023110993
LinkDB
Position
B3:41170312..41313975
AA seq 4887 aa
MATMVPPVKLKWLEHLNSSWITEDSESIATREGVAVLYSKLVSNKEVVPLPQQVLCLKGP
QLPDFERESLSSDEQDHYLDALLSSQLALAKMVCSDSPFAGALRKRLLVLQRVFYALSNK
YHDKGKVKQQQHSPESSSGSADVHSVSERPRSSTDALIEMGVRTGLSLLFALLRQSWMMP
VSGPGLSLCNDVIHTAIEVVSSLPPLSLANESKIPPMGLDCLSQVTTFLKGVTIPNSGAD
TLGRRLASELLLGLAAQRGSLRYLLEWIEMALGASAVVNSMEKSKLLSSQEGMISFDCFM
TILMQMRRSLGSSADRSQWREPTRTSDGLCSLYEAALCLFEEVCRMASDYSRTCASPDSI
QTGDTPIVSETCEVYVWGSNSSHQLVEGTQEKILQPKLAPSFSDAQTIEAGQYCTFVIST
DGSVRACGKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVF
SWGDGDYGKLGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDF
GRLGHGDSNSRNIPTLVKDISNVGEVSCGSSHTIALSKDGRTVWSFGGGDNGKLGHGDTN
RVYKPKVVEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGACLGCGSSEATALRPKLIE
ELAATRIVDISIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLDGIAI
QQISAGTSHSLAWTALPRDRQVVAWHRPYCVDLEESTFSHLRSFLERYCDKINSEIPPLP
FPSSREHHSFLKLCLKLLSNHLALALAGGVATSILGRQAGPLRNLLFRLMDSTVPDEIQE
VVIETLSVGATMLLPPLRERMELLHSLLPQGPDRWESLSKGQRMQLDIILTSLQDHTHVA
SLLGYSSPSDAADLSSVCTGYGNLSDQPYGTQSCHPDTHLAEILMKTLLRNLGFYTDQAF
GELEKNSDKFLLGTSSSENSQPAHLHELLCSLQKQLLAFCHINNISENSSSVALLHKHLQ
LLLPHATDIYSRSANLLKESPWNGSVGEKLRDVIYVSAAGSMLCQIVNSLLLLPVSVARP
LLSYLLDLLPPLDCLNRLLPAAALLEDQELQWPLHGGPELIDPAGMPLPQPAQSWVWLVD
LERTIALLIGRCLGGMLQGSPVSPEEQDTAYWMKTPLFSDGVEMDTPQLDKCMSCLLEVA
LSGNEEQKPFDYKLRPEIAVYVDLALGCSKEPARSLWISMQDYAVSKDWDSATLSNESLL
DTVSRFVLAALLKHTNLLSQACGESRYQPGKSLSEVYRCVYKVRSRLLACKNLELIQTRS
SSRDRWISENQDSADVDPQEHSFTRTIDEEAEMEEQAERDREEGHPEPEDEEEEREHEVM
TAGNLVFVLHVTEIFQCFLSAREVARSRDRDRMNSGAGSGARADDPPPQSQQERRVSTDL
PEGQDVYTAACNSVIHRCALLILGVSPVIEELQKRKEEGQLQQPSTSASEGGGLMTRSES
LTAESRLVHASPNYRLIKSRSESDLSQPESDEEGYALSGRRNVDLDLASSHRKRGPMHSQ
LESLSDSWARLKHSRDWLCNSSYSFESDFDLTKSLGVHTLIENVVSFVSGDVGNAPGFKE
PEESMSTSPQASIIAMEQQQLRAELRLEALHQILVLLSGMEEKGSISLTGSRSNLGFQSS
TLLTSVRLQFLAGCFGLGTVGHAGAKGESGRLHHYQDGIRAAKRNIQIEIQVAVHKIYQQ
LSATLERALQANKHHIEAQQRLLLVTVFALSVHYQPVDVSLAISTGLLNVLSQLCGTDTM
LGQPLQLLPKTGVSQLSTALKVASTRLLQILAITTGTYADKLSPKVVQSLLDLLCSQLKN
LLSQAGVLLMASFGEGEGEEGEEEERKVDSSGETEKRDFRAALRKQHAAELHLGDFLVFL
RRVVSSKAIQSKMASPKWTEVLLNIASQKCSSGIPLVGNLRTRLLALHVLEAVLPACESG
VEDDQMAQVVERLFSLLSDCMWETPIAQAKHAIQIKEKEQEIKLQKQGELEEEDENLPIQ
EVSFDPEKAQCCLVENGQILTHGSGGKGYGLASTGVTSGCYQWKFYIVKENRGNEGTCVG
VSRWPVHDFNHRTTSDMWLYRAYSGNLYHNGEQTLTLSSFTQGDFITCVLDMEARTISFG
KNGEEPKLAFEDVDAAELYPCVMFYSSNPGEKVKICDMQMRGTPRDLLPGDPICSPVAAV
LAEATIQLIRILHRTDRWTYCINKKMMERLHKIKICIKESGQKLKKSRSVQSREENEMRE
EKESKEEEKGKHNRHGLADLSEPQLRTLCIEVWPVLAVIGGVDAGLRVGGRCVHKQTGRH
ATLLGVVKEGSTSAKVQWDEAEITISFPTFWSPSDTPLYNLEPCEPLPFDVARFRGLTAS
VLLDLTYLTGIHEDMGKQSTKRHEKKHRHESEEKGDVEQKTESESALDTRTGLTSDDVKN
QGTTASKSENEIASFSLDPTLPSVESQHQITEGKRKNHEHISKNHDIAQSEIRAVQLSYL
YLGAMKSLSALLGCSKYAELLLIPKVLAENGHNSDCASSPVVHEDVEMRAALQFLMRHMV
KRAVMRSPIKRALGLADLERAQAMIYKLVVHGLLEDQFGGKIKQEIDQQAEESDQAQQAQ
TPVTTSPSASSTTSFMSSSLEDTTTATTPVTDTETVPASESPGVMPLSLLRQMFSSYPTT
TVLPTRRAQTPPISSLPTSPSDEVGRRQSLTSPDSQSARPANRTALSDPSSRLSTSPPPP
AIAVPLLEMGFSLRQIAKAMEATGARGEADAQNITVLAMWMIEHPGHEDEEEPQPGSTAD
SRHGAAVLGSGGKSNDPCYLQSPGDIPSADAAEMEEGFSESADNLDHAENAASGSGPPAR
GRSAVTRRHKFDLAARTLLARAAGLYRSVQAHRNQSRREGISLQQDPGALYDFNLDEELE
IDLDDEAMEAMFGQDLTSDNDILGMWIPEVLDWPTWHVCESEDREEVVVCELCECSVVSF
NQHMKRNHPGCGRSANRQGYRSNGSYVDGWFGGECGSGNPYYLLCGSCREKYLALKTKSK
TTSSERYKGQAPDLIGKQDSVYEEDWDMLDVDEDEKLTGEEEFELLAGPLGLNDRRIVPE
PVQFPDSDPLGASVAMVTATNSMEETLMQIGCHGSVEKSSSGRITLGEQAAALANPHDRV
VALRRVTAAAQVLLARTMVMRALSLLSVSGSSCSLAAGLESLGLTDIRTLVRLMCLAAAG
RAGLSTSPSAMASTSERSRGGHSKASKPISCLAYLSTAVGCLASNTPSAAKLLVQLCTQN
LISAATGVNLTTVDDPIQRKFLPSFLRGIAEENKLVTSPNFVVTQALVALLADKGAKLRP
NYDKSEVEKKGLTAQLYAHPSYDPSAVGPLELANALAACCLSSRLSSQHRQWAAQQLVRT
LAAHDRDNQTTPQTLADMGGDLRKCSFIKLEAHQNRVMTCVWCNKKGLLATSGNDGTIRV
WNVTKKQYSLQQTCVFNRLEGDAEESLGSPSDPSFSPVSWSISGKYLAGALEKMVNIWQV
NGGKGLVDIQPHWVSALAWPEEGPATAWSGESPELLLVGRMDGSLGLIEVVDVSTMHRRE
LEHCYRKDVSVTCIAWFSEDRPFAVGFFDGKLLLGTKEPLEKGGIVLIDAHKDTLVSMKW
DPTGHILMTCAKEENVKLWGPISGCWRCLHSLCHPSIVNGIAWCSLPGKGSKLHLLMATG
CQSGLVCVWRIPQDTTQTSVTSSEGWWDQESNCQDGYRKSAGAKCVYQLRGHITPVRTVA
FSSDGLALVSGGLGGLMNIWSLRDGSVLQTVVIGSGAIQTTVWIPDVGVAACSNRSKDVL
VVNCTAEWAAANHVLATCRTALKQQGVLGLNMAPCMRAFLERLPMMLQEQYAYEKPHVVC
GDQLVHSPYMQCLASLAVGLHLDQLLCNPPVPPHHQNCLPDPASWNPNEWAWLECFSTTI
KAAEALTNGAQFPESFTVPDLEPVPEDELTFLMDNSKWINGMDEQIMSWATSRPEDWHLG
GKCDVYLWGAGRHGQLAEAGRNVMVPAAAPSFSQAQQVICGQNCTFVIQANGTVLACGEG
SYGRLGQGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDYGKL
GHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTSNK
KLPERVTALEGYQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKLGLGNSTAKSSPQKVD
VLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRARNHNRPQQIPVLAGVVIE
DVAVGAEHTLALASTGDVYAWGSNSEGQLGLGHTNHVREPTLVTVLQGKNVRQISAGRCH
SAAWTAPPVPPRAPGVSVPLQLGLPDAVPPQYGALREVSIHTARARLRLLYHFSDLMYSS
WRLLNLSPNNQNSTSHYNAGTWGIVQGQLRPLLAPRVYTLPMVRSIGKTMVQGKNYGPQI
TVKRISTRGRKCKPIFVQIARQVVKLNASDLRLPSRAWKVKLVGEGADDAGGVFDDTITE
MCQELETGIVDLLIPSPNATAEVGYNRDRFLFNPSACLDEHLMQFKFLGILMGVAIRTKK
PLDLHLAPLVWKQLCCVPLTLEDLEEVDLLYVQTLNSILHIEDSGITEESFHEMIPLDSF
VGQSADGKMVPIIPGGNSIPLTFSNRKEYVERAIEYRLHEMDRQVAAVREGMSWIVPVPL
LSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMR
FVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAI
NNCRSIDMDNYMLSRNVDNAEGSDTDY
NT seq 14664 nt   +upstreamnt  +downstreamnt
atggcaactatggttccaccagtgaaactgaaatggcttgaacacctgaacagctcctgg
attacagaggatagtgaatctattgctacaagagagggagttgctgttctgtattctaaa
ctggtcagcaataaagaagtagtacctttgccccaacaagttttgtgcctcaaaggacca
cagttgccagactttgaacgtgagtctctttcaagtgatgagcaggaccactatttggat
gcccttcttagcagccagctagcactagcgaagatggtatgttcagattccccatttgct
ggggcacttcgaaaacgactgcttgtactccagcgtgtcttttatgcactttctaataaa
taccatgacaaaggcaaagtgaaacagcagcagcattctccggagagcagctctggttca
gcagatgtccattctgttagtgaacgtccccggtcaagcactgatgcacttatagaaatg
ggtgttcgaactggtctaagtttattatttgcacttctaagacaaagttggatgatgcct
gtgtcaggacctggtcttagtctttgcaacgacgttattcatactgcaattgaagttgtc
agctctttgccaccattatctttagcaaatgaaagcaagattcctccaatgggtttggac
tgcttatcacaagtgacaacatttcttaaaggagtaactattcccaattctggggcagac
actttaggtcgcagattagcttctgagttgctacttggtttagcagctcagcgaggctct
ttgcggtaccttcttgaatggatagaaatggctttgggggcttcagcggttgtaaattcc
atggagaaaagcaaactactatcaagccaggaaggaatgatcagctttgactgctttatg
actatattaatgcagatgaggcgttctttgggttcatctgctgatcgaagtcagtggagg
gaaccaaccagaacatctgatggcttgtgctcactctatgaggcagctttatgtctcttt
gaagaggtttgcagaatggcttctgattactcaagaacgtgtgctagcccagatagcatt
cagactggtgacactcccattgtctcagaaacctgtgaggtctatgtttgggggagcaat
agcagccatcagttggtggaaggcacacaggagaaaatattacagcccaaactggctccc
agtttctctgatgctcaaactattgaagctgggcaatactgcacttttgttatttctacg
gatggctctgtcagagcttgtggtaaaggcagctatggaagactgggccttggagattct
aataatcagtccactttaaagaagttaacatttgaacctcacaggtccattaaaaaggtt
tcatcttctaaaggatctgatggtcacactttagcttttacaacagaaggagaagtcttc
agttggggagatggtgattatgggaaactgggacatggaaatagttcaacacagaaatac
cccaagcttattcagggccctctgcagggaaaggtagttgtttgtgtgtctgctggatac
agacatagtgctgctgtcacagaggatggtgaattatacacatggggtgaaggagacttt
ggaagattaggtcacggtgacagtaatagccgtaacattccaacattagtgaaagacatt
agcaacgtaggagaggtttcttgtggcagttcacatactattgctttgtctaaagatggg
agaactgtatggtcttttggaggaggagacaatggcaaacttggccatggcgatactaac
agagtgtataaacctaaagttgttgaagctttacaaggaatgttcattcgcaaagtttgt
gctgggagccagtcttcacttgctttaacatcaacagggcaggtctatgcttggggctgt
ggagcttgtctgggttgtggttcttcagaagctactgctttgagacccaagcttattgaa
gaactggctgccacaagaatagttgatatttctattggagacagtcattgtttggctctt
tctcatgataatgaagtttatgcctggggcaataattcgatggggcagtgtggccaagga
aattccacaggtcctattactaaaccaaagaaagtgagtggcttagatggcatagctatt
cagcagatttctgctggaacttcacatagtctggcatggactgctcttcctagggataga
caagttgttgcgtggcaccgaccttattgtgtagatcttgaagagagtaccttctcacac
ctgcgttcttttcttgagagatactgtgataaaataaacagtgagattcccccactccct
ttcccttcatcaagggagcaccacagtttcctcaagctgtgcctgaagctgctttcaaat
caccttgctcttgcgcttgcgggaggggtagctaccagcattcttgggagacaggcaggt
ccgcttcgaaatttgctcttcagactgatggattcaactgtcccagatgaaattcaagag
gtggtaattgaaactctgtcagtgggagcaaccatgctattaccgccattacgcgaacgt
atggagttacttcattctcttttgccccaaggacctgatagatgggaaagcttatctaaa
ggacagagaatgcaactggatatcattctgacaagtttacaagaccatacccatgtagct
tccttacttggctatagctcaccttctgatgctgctgacctctcttctgtttgtactggc
tatggaaacctgtcagatcaaccttatggcactcagagctgccatccagacactcacctg
gctgaaattttgatgaaaactctcttaagaaatttaggattttatacagatcaagcattt
ggagagctagaaaagaatagtgataaatttctgcttggaacatcatcttcggaaaacagt
cagcctgctcatcttcatgaactcctgtgttcactgcagaaacaactgctggcattttgc
catatcaataacattagtgagaactcaagcagcgtggcattgcttcataaacaccttcag
ctcttgttgcctcatgccacagatatttattcacgttcggcaaatttgctcaaggaaagt
ccttggaatggcagtgttggagaaaaattaagagatgtgatatacgtctcagctgcaggg
agtatgctctgccagattgttaactccctactgttactccctgtgtcggtggcacggcct
ctcttgagttacctcctcgacttgttgccacctcttgattgccttaacagactcctgcca
gctgccgctcttttagaagaccaagagttacagtggcctcttcatggaggaccagaactg
attgatcctgctggcatgccgttacctcagccagctcagtcctgggtgtggcttgtggat
ctggaaagaacgattgctctccttattgggcggtgtcttggtggtatgcttcagggctcc
cctgtgtctccagaggaacaggacaccgcatattggatgaaaacaccactttttagtgat
ggtgtagaaatggacacccctcagttagataaatgtatgagttgcctgctagaagtagct
ctttcgggaaatgaagaacagaagccttttgattataaactgcggcctgaaattgctgtc
tatgtagacttggcattgggttgttcaaaagagcctgctcgaagtctttggataagcatg
caggattatgctgttagtaaagattgggacagtgcaactttaagtaacgagtcactcttg
gacactgtgtctagatttgttcttgcagctcttctgaaacatacaaatttacttagccaa
gcatgtggagaaagccgatatcagcctggtaaaagcttgtcagaagtgtaccgttgtgtg
tacaaagttcgaagtcgtttacttgcttgcaagaaccttgaacttattcagaccaggtca
tcatcacgagacagatggatctcggaaaaccaggactctgcagatgttgatcctcaggag
cattcgtttacccggaccattgatgaagaagctgaaatggaagaacaggctgagcgagac
cgggaagaggggcatcccgagccagaggatgaagaagaagaacgggaacatgaagtgatg
acagctggcaaccttgtttttgtgttgcatgttacagaaatctttcagtgtttcctctca
gcccgtgaagtagctcgtagccgagatcgagatagaatgaacagtggggcagggtctggg
gctcgagctgatgatccacctccccagtctcagcaagagcgaagggtcagcacagacctt
cctgagggtcaggatgtgtacaccgctgcctgcaactctgtgatccatcggtgtgccctg
ttaatattaggagtaagtcctgtgattgaggagcttcagaagcggaaggaagaaggacag
ttgcagcagccttcaacaagtgcctctgaagggggtggacttatgaccaggagtgaaagt
cttactgcagagagccggctagtccatgcaagtccaaattatagactgatcaaatcgagg
agtgaatctgatttgtctcagcctgaatcagatgaagagggttacgcgctgagtggaaga
cgaaatgttgatttggatttggcatcatctcatagaaagagaggtcctatgcacagtcaa
ttggaatccttgagtgactcttgggctcgcctgaaacatagcagagactggttatgcaac
tcctcttactcctttgagtctgattttgatcttaccaagtctttgggagttcacactttg
atcgaaaatgttgtaagctttgtgagtggagatgtggggaatgctccaggttttaaagag
ccagaggaaagtatgtctacgagtccccaggcctctatcattgcaatggaacagcagcag
ttaagggcagaactacgtttagaagcacttcaccagatcctcgttcttttgtctgggatg
gaggaaaaaggaagcatctctctgacaggaagcagatcaaacttgggcttccagtcatcc
acactgctcacgtctgtgaggctgcagtttctagcagggtgttttggtttaggcactgtg
ggacatgcaggagccaaaggagagagtggccgattgcatcactatcaggatgggatcaga
gcagctaaaagaaatattcagattgaaatccaggtggctgtgcataagatttatcaacag
ttgtctgctaccctagagagagctctacaggcaaataagcatcacattgaagcccagcaa
cgtctccttttggttacagtttttgctctgagcgttcactatcaaccagtggatgtttct
ttggcaatttccactggtctgctaaacgtattgtcgcagttatgtggtacagacaccatg
ctgggacagcctctgcagttactgccaaagacgggtgtttctcagcttagtacagcttta
aaagtggctagtacaagattgctccaaattctagctatcactacagggacttacgctgat
aaactgagccccaaagtagttcagtccttgttggatctactctgtagtcagttgaagaat
ttgttgtcccaagctggtgtactacttatggcctcttttggagaaggggaaggagaagag
ggtgaagaagaagaaagaaaagttgactccagtggagagactgagaagagagatttcaga
gctgctcttaggaaacaacatgcagcagaactgcatctgggggattttttagtttttctt
cgcagagttgtatcttcaaaagcaattcaatcaaaaatggcttctccaaaatggacagag
gtgcttctaaacatagcatctcagaagtgttcttcaggtattcctctcgttggtaaccta
agaacaaggctccttgcacttcatgtccttgaggctgtgctaccagcttgtgaatctggc
gtagaagatgatcaaatggctcaggttgttgaacgcctcttttcccttctgtcggactgt
atgtgggagacacccattgctcaggccaaacatgctattcagataaaggaaaaagaacaa
gaaataaagttacagaagcagggagagttagaggaagaagatgagaatcttcctatacaa
gaagtatcctttgatccagagaaagctcagtgttgtctagtggagaatggacagatttta
actcatggcagtggaggaaaaggatatggattggcatcaactggagtaacttctggatgc
tatcagtggaagttttacattgtgaaggaaaacagaggtaatgaaggcacgtgtgttgga
gtttctcgctggccagtacatgactttaaccaccgtactacctccgatatgtggctgtac
cgggcctacagtggtaacctctatcacaatggagaacagactctgacgttgtccagtttt
actcaaggagatttcattacctgtgtgttagacatggaagccagaaccatttcctttggg
aaaaatggagaggaacccaaattggcttttgaagatgtggacgcagcagagttatacccg
tgtgtaatgttctatagtagcaacccaggggagaaggtgaaaatttgtgatatgcaaatg
cgtgggacaccacgagacttacttccaggagaccctatttgtagtccagtagcagcagtg
ctggcggaggccactattcagcttatccgtatccttcaccgaacagaccgttggacttac
tgcattaacaaaaaaatgatggaaaggctgcataaaattaagatatgtattaaagagtca
ggtcagaagctaaagaaaagccgctcggttcaaagccgagaggaaaatgaaatgagagag
gagaaggaaagcaaagaggaagagaaaggtaaacataatagacatggccttgctgacctc
tcagagccgcagctgaggaccctttgcatagaggtgtggcctgtgctggcagtgatagga
ggagttgatgctggtcttagagttggaggtcggtgtgttcacaagcaaactgggcgccat
gccacgctgctgggagtggtcaaagagggcagcacgtctgctaaggtccaatgggatgaa
gcagaaattaccatcagcttcccaactttttggtcgcctagtgatactccattgtataat
ctggagccctgtgaaccattgccttttgatgtggcgcgattccgaggcctgacggcttct
gtgttgctggacctcacatatctgactggtattcatgaagacatgggcaaacagagcacc
aagcgacatgaaaagaaacaccgacatgagtctgaggagaaaggagatgttgagcagaaa
accgagagtgaatctgctttagatacacgaacaggcttaacatccgatgatgtcaaaaat
cagggtaccacagcctccaaatccgaaaacgaaatagcttcattttctttagacccaaca
ctgccaagtgtggaatcccaacatcagataacagaaggaaaaagaaaaaatcacgaacac
atatccaaaaaccatgacatagcccaatcagaaatcagagcagtccaactgtcctatctc
tacctcggtgctatgaaatcacttagtgctcttcttggctgtagtaaatatgctgagctg
ttgctgataccaaaagttctggctgaaaatggccataactcagactgtgcaagctctcca
gttgttcatgaagatgtagagatgcgagcagccttgcagttcctgatgcgacacatggtg
aagcgagctgtcatgcggtcgcccataaagagagcgttgggattagctgatctggaacga
gctcaagccatgatctacaaattggtggtccatgggctcctggaagaccagtttgggggc
aaaattaagcaagagattgatcaacaagctgaagaaagtgaccaagcgcagcaggcacaa
acaccagttaccactagcccatcagcctcgagcacaacttcctttatgagcagctcgctg
gaagacaccacgactgccaccactccagtcactgacacagaaacagtacctgcatctgaa
tccccaggagtgatgccacttagtcttctcaggcaaatgttctctagttacccaactacc
actgtacttcccacacgtcgtgcacagactcctccaatatcatcgttaccaacctctcct
tctgatgaagtaggaagaaggcaaagcttaacttctcctgattcccagtcagcaaggcca
gctaaccgcacagccttgtcagacccaagcagcaggctctcaacttctcctcctcctcca
gcaattgcagtacccttgctggagatggggttctctctccggcagattgccaaagccatg
gaagccacaggtgctcgaggagaggctgatgcccagaacatcactgtccttgccatgtgg
atgatagagcaccctgggcatgaggatgaggaggaaccccagccaggtagcacagctgac
tcaagacacggagcagctgtcctaggcagtggtgggaagtcaaatgatccctgttatttg
cagtcaccaggagacataccatcagctgatgctgctgaaatggaagaaggctttagtgaa
agcgctgataatctggaccatgcagagaatgcagcttctggaagtggaccaccagctagg
ggtcgctcagcagtaacaagaaggcacaagtttgatttagctgctcgcacattgctagca
agagcagcggggttataccgctctgtgcaggcccacaggaatcaaagtcggagagaagga
atatctttgcaacaagacccaggggcgttgtatgactttaatttagatgaggaattggaa
attgatcttgatgatgaagcaatggaagctatgtttggacaagacctgaccagtgacaat
gatattctgggaatgtggatcccagaggtactggattggcctacctggcatgtttgtgag
tctgaagacagggaagaagtggtggtgtgtgaactgtgtgagtgcagtgtcgtcagcttc
aaccagcacatgaagagaaatcacccaggctgtgggcgcagtgcaaaccgccagggctat
cgcagcaacggctcctatgtggatggctggttcggtggtgaatgtgggagtggaaatcca
tactacctgctctgcggcagctgcagggaaaagtacttagccctgaagaccaaatccaag
acaacaagttctgaaaggtacaagggacaagctccagatctaattggcaagcaggacagt
gtgtatgaagaagactgggacatgttagatgttgatgaagatgaaaagctaacaggtgaa
gaagaatttgaattgcttgctggaccacttggtttaaatgaccgacgcattgtaccagaa
ccagttcagttccctgacagtgatcccttgggagcatcagtagcaatggtaacagctacc
aacagtatggaagagactctaatgcaaataggttgccatggctctgtagaaaagagttcc
tctggaagaataacactaggtgagcaggctgctgccttagcaaaccctcacgaccgggtg
gtggctttaaggagagtgactgctgctgctcaggttcttctggcaagaaccatggtaatg
agagctctgtctcttctctcggtcagtggttccagctgtagcctggctgctggcctggag
tctctggggcttacagatatccgaacactggttcggttaatgtgcttggccgcagcaggg
agagctggcctttctaccagcccttctgccatggcaagcacctcagaacgctcacgaggc
gggcacagcaaggccagtaagcccatctcttgcctggcctatctgagcacagcagtggga
tgtctggcatcaaacactcctagtgctgccaaactcctggtgcagttgtgtacacagaac
ttgatttctgctgcaacaggtgtaaatctaaccacggtcgatgatccaattcagcgaaag
tttctacccagctttctccgaggaattgctgaagagaataagcttgtaacctccccaaac
tttgttgtaactcaggcccttgtggcattactagcagacaagggggccaaactgagacct
aactatgataaatctgaagttgaaaagaaaggtttaactgcccaattgtatgcccatcct
tcctatgatccttctgctgtaggccctctggagctggctaatgccctggcagcctgctgc
ctctcctccaggctgtcctcacagcataggcaatgggctgctcaacagcttgtgcgcact
cttgctgcacatgaccgcgacaaccaaactactccccaaacactcgctgatatgggagga
gatctcaggaaatgctcctttatcaagttggaggctcatcaaaacagagtgatgacttgt
gtttggtgtaataaaaaaggacttttggctacaagtggcaatgatggtaccatccgggta
tggaatgttactaagaagcaatattcactgcaacaaacctgtgtgttcaacagattagaa
ggagatgctgaggagagcctggggtcacccagtgatccaagtttctcacctgtttcctgg
agtatcagtggcaaatatctagctggggccttggaaaagatggtgaatatttggcaagtt
aatggaggtaaaggattagtagatattcagcctcattgggtatctgccctggcttggcca
gaagagggtccagctacagcctggtcaggagagtctccagaattattgttggtgggacgg
atggatggctctctaggactgatagaagttgttgatgtatccaccatgcaccgtcgagaa
ttggaacattgctatcgaaaagatgtgtctgtaacttgcattgcttggttcagtgaagac
agaccatttgcagtaggattttttgatggaaaattgttactgggaacgaaggaaccactt
gagaaaggaggcattgttctaattgatgcacataaggatactcttgttagtatgaagtgg
gacccaacaggtcatattcttatgacatgtgccaaagaagaaaatgtgaaactctggggg
cctatttcaggatgctggcgctgtctacattcactctgccatccatctattgtaaatggc
attgcttggtgcagcctcccagggaaaggatccaaattgcatttactgatggctactggc
tgtcagagtggcttggtatgtgtttggcgtattccacaagataccacacagaccagtgtg
actagttcagaaggatggtgggaccaggagtcaaattgccaggatggatataggaaatca
gccggagccaaatgtgtttatcagctgcggggacacatcacccctgtccggactgttgcc
tttagttctgatgggttggccctcgtgtctggtggactaggtgggctcatgaacatttgg
tctttaagggatggctctgtcttgcaaactgtagtgataggctctggagctattcagacc
acagtatggattccagatgtcggggtagctgcttgctcaaatagatcgaaggatgttttg
gtcgtgaattgtacagcagaatgggctgccgccaatcatgttttagcaacctgtaggaca
gcactgaaacagcagggtgttctgggattaaatatggctccctgcatgagagcatttctg
gagcggctacccatgatgcttcaggagcagtatgcctatgaaaagcctcatgtggtttgt
ggcgatcagcttgttcatagcccctacatgcaatgtctggcttccctcgctgtgggactg
catttggatcagctgttatgtaaccctccagtgccaccacaccaccagaactgcctccct
gacccagcatcctggaatccaaatgagtgggcctggttagaatgtttctcaaccaccata
aaagctgctgaagccctgaccaacggagcacaatttccagaatcttttactgttcctgat
ctagagcctgttccagaggatgagcttacattcctaatggataacagtaaatggattaat
ggcatggatgaacaaattatgtcttgggcaacatccagacctgaggactggcacttggga
ggtaaatgtgatgtctacctgtggggtgctggcaggcatggacagcttgcagaagctgga
agaaatgttatggtacctgcagcagctccctcattctcacaggcccaacaggtcatatgt
ggtcagaattgtacttttgtcatccaggccaatggcacagtgttggcttgtggggaagga
agttatggcagattggggcaaggaaattcagatgaccttcatgtgctgacagttatttca
gccttacaaggatttgtggtgacccagctggtgacatcttgtggctctgatggtcactca
atggccctgactgaaagtggtgaggtctttagctggggagatggcgattatggcaaactc
ggccacgggaacagcgacaggcagcggcgccccaggcagatcgaggccttacaaggagaa
gaagtggtgcagatgtcttgtggcttcaagcactcagcagtggtaacttcagacggcaaa
ctgttcacttttgggaatggtgactacggtcgtctgggtcttggaaacacctctaacaaa
aaactaccagagagagtgactgcactggagggatatcagattggacaggtggcctgtggt
ttaaaccacactttggcagtatcagcagacggctccatggtgtgggcttttggagatggg
gactatggaaaactaggcttaggaaattccactgcaaaatcttcccctcagaaagttgat
gtcctttgtggaattggaataaaaaaggttgcttgtggaactcagttttctgttgcatta
accaaagatggtcatgtgtatacctttggtcaagatcgcttgataggcttgccagagggg
cgtgctcgcaatcataaccgaccacagcagatccctgtgctggctggagtggtcatcgaa
gatgtggcagttggagctgagcacactcttgctttggcatcaactggagatgtgtatgcc
tgggggagcaattcagaagggcagcttggcttaggccacaccaaccatgttcgagaacca
accctggtaacagtcctgcaagggaaaaatgtccggcagatctcagctggccgctgccac
agtgctgcatggacagcgccacctgtcccgccaagagcacccggtgtgtcggtacctctg
cagctgggcctgcccgatgcggtccccccccagtatggggcgctgagggaggtgagcatt
cacactgcgagggcgaggctccggctgctctaccatttctctgacctcatgtactcatct
tggaggctactgaacctcagccccaacaaccagaacagtacatcccattataatgctgga
acatggggcattgtacagggacagcttcggcctttgttagctccaagggtctacaccctg
ccaatggtgcgctccatagggaaaaccatggttcaaggcaaaaactatggacctcaaatt
actgtgaagaggatatcaaccagaggacggaagtgtaagcccatctttgtccagatagca
agacaagtagttaagctgaatgcatcagacctccgtctgccctcacgagcgtggaaggtt
aagctggttggtgaaggggcggatgatgctgggggagtgtttgatgacacgatcacagag
atgtgccaggaacttgaaactggtattgttgaccttcttataccctctcccaatgctact
gcagaagtgggctacaatagggataggttcctttttaacccctctgcctgccttgacgaa
cacttaatgcagtttaagttcttggggatcttgatgggggttgccattcgcacaaagaag
cctctggacctccacttggcccctttggtgtggaagcagctgtgctgtgtcccactcacc
ctagaagacctggaggaggtggatctgctctacgtgcagaccctcaacagcattcttcac
attgaagacagtgggattaccgaggaaagtttccatgagatgattcctcttgattctttt
gttggccaaagtgctgatggcaaaatggttcccataatccctggtggaaatagtatccca
ctgacattttccaacaggaaggagtatgtggagagggccattgaatatcgacttcatgag
atggaccgacaggtggctgcagtccgagaagggatgtcctggatcgtccctgtgccgctg
ctgtccctcctcacggcaaagcagctggagcaaatggtgtgtgggatgcccgagatctcc
gtggaagttctgaagaaagtggtgcggtaccgggaggtggacgagcagcaccagctggtg
cagtggttctggcacacgctggaggagttctcgaacgaggagcgggtgcttttcatgagg
tttgtgtctggaagatctcgactaccagccaacactgctgacatatctcagagatttcaa
atcatgaaggttgataggccttatgacagtctgcctacctcacagacctgcttcttccag
ctgcggctgcccccctactccagccagctggtcatggccgagcgcctgcgctatgccatc
aacaactgccgctccatcgacatggacaactacatgctctcgcggaacgtggacaacgcc
gagggctccgacaccgactactga

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