Felis catus (domestic cat): 101090171
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Entry
101090171 CDS
T02385
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04217
Necroptosis
fca04380
Osteoclast differentiation
fca04621
NOD-like receptor signaling pathway
fca04630
JAK-STAT signaling pathway
fca04658
Th1 and Th2 cell differentiation
fca04659
Th17 cell differentiation
fca05145
Toxoplasmosis
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05162
Measles
fca05164
Influenza A
fca05165
Human papillomavirus infection
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05168
Herpes simplex virus 1 infection
fca05169
Epstein-Barr virus infection
fca05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
101090171 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
101090171 (TYK2)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
101090171 (TYK2)
04658 Th1 and Th2 cell differentiation
101090171 (TYK2)
04659 Th17 cell differentiation
101090171 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
101090171 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
101090171 (TYK2)
05160 Hepatitis C
101090171 (TYK2)
05171 Coronavirus disease - COVID-19
101090171 (TYK2)
05164 Influenza A
101090171 (TYK2)
05162 Measles
101090171 (TYK2)
05168 Herpes simplex virus 1 infection
101090171 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
101090171 (TYK2)
05169 Epstein-Barr virus infection
101090171 (TYK2)
05165 Human papillomavirus infection
101090171 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101090171 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101090171 (TYK2)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101090171 (TYK2)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
101090171 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
Kdo
Kinase-like
APH
ABC1
RIO1
Motif
Other DBs
NCBI-GeneID:
101090171
NCBI-ProteinID:
XP_023101019
Ensembl:
ENSFCAG00000009436
LinkDB
All DBs
Position
A2:complement(7846299..7864550)
Genome browser
AA seq
1194 aa
AA seq
DB search
MACLFPAKPAVKSMPLCRWGATTMDSRTDGDEAQPMVSRGGLKVLLHWAGPDGGDPWVTF
SEATLTAEEVCIHIAHKVGITPSCLNLFALFDAQAQVWLPPNHILEVSRDTNLTLYFRMR
FYFRNWHSMNPQEPAVYRCGPTRAKSSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVAP
LWELSSEEEIHHFKNESLGMAFLHLCHLALCHGIPLEKVAKKISFKDCIPRSFRLQLRRH
NALTRLRLRRLFRRFVRAFQPGHVSQPVIMVKYLATLEQLAPRFGTERVLVCRLEEQAQA
VGDPCYVQDGGQSPPEPGPELAPGPPTHEVLVTGTGGIRWRPVQAEGPGGDGCSRNPCAG
PSGKKSKAQEVGNQPVDRPQEAPWAYFCDFQDITHVVLKERHVSIHCQDKCLELTLPSRA
VALSLVSLVDGYFRLTADSSHYLCREVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLY
LIHWSTSHLNRLILTVAQRDQAPGGQQLHLRKFPIELRAGSFELEGWDRSFPSVRELRTA
LQGCSLRAGDDCFSLRRCCLPRPGELSNLIIMRGSRASPGPLNLSQLSFHRVCQDDITQL
SHLGQGTRTNVYEGILRVGERGPKEGTADGGDPPTPSGDRGQELRVVLKVLDPSHHDIAL
AFYETASLMSQVSHVHLAFVHGVCVHGSENIMVTEYVEHGPLDVWLRRERGHVPVAWKVA
VAQQLASALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREERV
ERIPWTAPECLSGGASTLTTAADKWGFGVTLLEICFDGEAPLQGRGPSEKECFYQKQHQL
PQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPASDPTVFH
KRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKAGGGPQLRTGWRREIDILRT
LYHKHIVKYKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHNVGLAQLLLFAQQICEGMAY
LHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECL
KECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGER
LPRPEKCPCEIYLLMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFNVC
NT seq
3585 nt
NT seq
+upstream
nt +downstream
nt
atggcctgtctcttcccagccaagccagctgtcaagagcatgcctctgtgccgttggggt
gccaccaccatggacagcaggactgatggggatgaggctcagcccatggtctccagggga
ggcctaaaggtccttctgcactgggctggccctgatggcggggacccttgggtcaccttc
agcgaggccacactgaccgcagaggaggtctgcatccacatcgcacacaaagtcggcatc
actccatcctgcctcaatctcttcgccctctttgatgcccaggcccaggtgtggctgccc
ccaaaccacatcttggaggtctccagagacacgaacctgacattgtacttccgcatgagg
ttttatttccggaactggcacagcatgaatcctcaggagccggccgtgtaccgctgtggg
cccaccagggccaagtcttcctcggaacaggcagagcagggggtgcaactcctggaccca
gcctcctttgagtacctctttgagcagggcaagcacgagtttgtgaatgatgtggcacca
ctgtgggagctgtcgagcgaggaggagatccaccattttaagaacgagagcctgggcatg
gcctttctgcacctctgccacctcgccctttgccatggtatccccctggagaaggtggcc
aagaagatcagcttcaaggactgcatcccacgctccttccggctgcagctccggcggcac
aacgcgttaacacggctgcgcctacggagactcttccgcaggtttgtgcgggccttccag
ccgggccacgtctcccagccggtcatcatggtcaagtacctggccacgctggagcagctg
gcaccccgcttcggcacggagcgcgtgctcgtgtgccggctggaggagcaggcccaggcc
gtgggggacccctgctacgtccaggacgggggccagtcccccccggagcctgggcctgaa
ttggcccccggaccccctactcatgaggtgctggtgacaggcactggtggcatccggtgg
cggccagtccaggcagagggtcccgggggcgatggttgcagcaggaacccctgtgctggc
ccatcagggaagaaaagcaaggcccaggaggtgggcaaccagccagtggacaggcctcag
gaagcgccatgggcctacttctgtgacttccaggacatcacccacgtggtgctgaaagag
cgccacgtcagcatccactgtcaggacaagtgcctggagctcaccctgccttcccgggct
gtggccctgtccttggtgtcgctggtggacggctatttccgcctgacggccgactcgagc
cactacctgtgccgggaggtggcccctccgcggctggtgatgagcatccgggatggcatc
cacgggcccttgctggagccattcgtgctggccaagttgcggcccgaagatggcctctac
ctcatccactggagcaccagccacctcaaccgtctcatcctcacggtggcccagcgtgac
caggcacctggcgggcagcagctgcacctccgtaaattccctattgagctgcgggccggg
agcttcgagctggagggctgggaccgctccttcccgagcgtgcgggagctgcgcaccgcc
ctgcagggctgctcgctgcgggccggggacgactgtttctccctgcgccgctgctgcctg
ccacggcccggagagctctccaacctcatcatcatgcgtgggtctcgggccagccctggg
ccactcaacctcagccagctcagcttccaccgcgtctgccaggatgacattacccagctg
tctcacttgggccaaggcacgaggaccaatgtgtatgagggcatcttacgggtgggggaa
agaggccccaaggagggcacggcagatggtggggatccccccacgcccagtggggaccgt
gggcaggagctccgagtggtactcaaggtgctggaccccagtcaccacgacatcgccctg
gccttctacgagacagccagcctcatgagccaggtctcccacgtgcacctggcctttgtg
cacggcgtctgcgtgcacggctctgagaacatcatggtgacagagtacgtggagcacgga
cccctggatgtgtggctgcggcgggagaggggccacgtgcctgtggcctggaaggtggca
gtggcccagcagctggccagcgctctcagctacctggaagacaagagcctggttcatggt
aatgtgtgtggccggaacatcctgctggcacggctgggactggcggagggcaccagcccc
ttcatcaagctgagcgatcccggtgtgggcctgggcgccctttccagggaggagcgggta
gagaggatcccctggacagcccccgagtgcctgtcaggtggggccagcaccctaaccact
gcagctgacaaatggggctttggtgtcaccctcctggagatctgcttcgacggggaggcc
cctctgcagggccgcggcccttctgagaaagagtgcttctaccagaagcagcaccagctt
cctcagccctcctgcccggagctggccacactcaccagccagtgcctgacctatgaacca
gctcagcggccctccttccgcaccatcctgcgtgacctcactcagctgcagccccagaat
cttgctgacgtcttggctgtgaaccccgactcgcctgcatcagaccccaccgttttccac
aagcgctatttgaaaaagatccgggatctgggcgagggtcatttcggcaaggtcagtctg
tattgctacgacccgactaacgacggcaccggcgagatggtggctgtgaaggccctcaag
gcgggcgggggcccccagctccgcactggctggcggcgggagatcgacatcctgcgcacg
ctctaccacaagcacatcgtcaaatacaagggatgctgtgaggaccaaggagagaagtcg
gtgcagctcgttatggagtacgtgcctctgggcagcctccgggactaccttccccggcac
aacgtcggactggcccaactgctactcttcgcccagcagatctgtgagggcatggcctac
cttcatgcacagcactacgtccaccgagacctggctgcccgcaacgtgctgctggacaac
gacaggctggtcaaaatcggggactttggcctagccaaggctgtgcctgaaggccatgag
tactaccgcgtgcgcgaagatggggacagccccgtgttctggtatgctccagagtgcctg
aaggagtgtaagttctactatgcatccgacgtctggtccttcggggtcaccatgtatgag
ctgctgacctactgtgactccagccagagccccccttcgaaattcatcgagctcataggc
ctcacccaagggcagatgacggtgctgaggctcactgagctgctggaacgaggggagagg
ctgccgcggccagagaaatgcccttgcgagatctacctcctcatgaagaactgctgggag
gcagaggcctcattccgccccactttccagaacctcatccccattctcaagacggtccag
gagaaataccaaggccaggccgcctcagtgttcaatgtgtgctga
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