Felis catus (domestic cat): 101090765
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Entry
101090765 CDS
T02385
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca04010
MAPK signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04020
Calcium signaling pathway
fca04072
Phospholipase D signaling pathway
fca04144
Endocytosis
fca04151
PI3K-Akt signaling pathway
fca04510
Focal adhesion
fca04540
Gap junction
fca04630
JAK-STAT signaling pathway
fca04810
Regulation of actin cytoskeleton
fca05163
Human cytomegalovirus infection
fca05200
Pathways in cancer
fca05206
MicroRNAs in cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05218
Melanoma
fca05230
Central carbon metabolism in cancer
fca05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101090765 (PDGFRA)
04014 Ras signaling pathway
101090765 (PDGFRA)
04015 Rap1 signaling pathway
101090765 (PDGFRA)
04630 JAK-STAT signaling pathway
101090765 (PDGFRA)
04020 Calcium signaling pathway
101090765 (PDGFRA)
04072 Phospholipase D signaling pathway
101090765 (PDGFRA)
04151 PI3K-Akt signaling pathway
101090765 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101090765 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101090765 (PDGFRA)
04540 Gap junction
101090765 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101090765 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101090765 (PDGFRA)
05206 MicroRNAs in cancer
101090765 (PDGFRA)
05230 Central carbon metabolism in cancer
101090765 (PDGFRA)
05231 Choline metabolism in cancer
101090765 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
101090765 (PDGFRA)
05218 Melanoma
101090765 (PDGFRA)
05215 Prostate cancer
101090765 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
101090765 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101090765 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101090765 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
fca04090
]
101090765 (PDGFRA)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101090765 (PDGFRA)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
101090765 (PDGFRA)
CD molecules [BR:
fca04090
]
Proteins
101090765 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
101090765
NCBI-ProteinID:
XP_003985426
UniProt:
M3WAV8
LinkDB
All DBs
Position
B1:complement(161740098..161792062)
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHLALLVLVCLLTGPSLISCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEVRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTDENEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPKTPVTLRSSDGVVHASYDSRQGFNG
TFSVGPYICEATVSGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEVRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTVLANNISNIITEVHRRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSTSDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKNGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKHEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFVKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccacctggcgctcctggtgttagtctgtctcctcacaggaccgagccta
atctcctgccagctttcattaccctctatccttccaaacgaaaatgaaaaggtcgtgcag
ctgaattcctccttttctctgcgatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaagtcagaaatgaagaaaacaacagtggcctt
tttgtgacggtgctggaagtggtcaatgcgtcggcggcccacacgggactgtacacttgc
tattacaaccacactcagacggacgaaaacgagatcgaaggcaggcgcatttacatctat
gtcccagacccagacgtagccttcgtacctctaggaatgacagattatttagttatcgtg
gaggacgatgactctgccatcataccttgtcgcacaactgatcccaagactccggttacc
ttacgcagcagtgacggggtggtacacgcctcctatgacagcagacagggctttaatggg
accttcagcgtcgggccctatatctgcgaagccacagtcagcgggaagaagttccagacc
atcccatttaatgtttacgctttaaaagcaacatcagaacttgatcttgaaatggaagct
ctcaaaactgtctataagtcaggggagacgattgtggtcacctgcgccgtctttaacaac
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacgatg
ctggaggagatcaaggtcccgtccatcaaactggtttacactctgacggtccccgaggcc
acggtgaaggatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttccgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaggctgtcgacctgcatgaagtcaaacatttcgtggtggacgtgcag
gcctacccgcctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccaccgacatagaaaagattcaggaagtaaggtatcgaagcaaattaaag
ctgatccgtgcgaaggaagaagacagtggccattacactattgtcgtccaaaatgaagac
gacgtgaagagctatactttcgaactcttaacgcaagttccttcgtctattctggacttg
gtcgacgaccaccatggctccaccgggggacagactgtgagatgcacagcagaagggaca
cctcttcctgatatcgagtggatgatttgcaaggatattaagaaatgtaataacgaaact
tcatggacggttttggcgaacaacatctcgaacatcatcacggaagtccaccgccgggac
aggagtactgtggagggccgagtgacgttcaccagagtggaggagaccatcgccgttcga
tgcctggccaagaatcttcttggagccgagaaccgagagctgaagctggtggctcccacg
ctgcgttctgaactcacagtggcggctgcagtcctggtcctgctggtgattgtgatcatc
tccctcattgtcctggtcgtcatttggaaacagaaaccgaggtatgaaattcgttggagg
gtcattgaatcgatcagccccgatggacatgaatatatttacgtggacccgatgcagctg
ccttatgactctagatgggagtttccaagagatggactagtgcttggtcgtatcctggga
tctggtgcgttcgggaaagtggtcgaaggaactgcctatggattgagccggtcccagcct
gtcatgaaagtagcagtaaagatgctaaaacccacagccagatccagtgaaaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccccatttaaacattgtgaacttg
ctgggggcctgcaccaagtcaggccctatttacatcatcacggagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgacacccagagaag
ccaaagaaagagttggacatttttgggctgaaccctgctgatgaaagcacacggagttac
gttattttatcttttgaaaacaatggtgactatatggacatgaagcaagcggataccaca
cagtacgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagagatcg
ctgtatgatcgcccggcctcgtataagaagaaatctacgtcagactcggaagtcaaaaac
ctcctctcggacgataactcagaaggcctgactctgctggatttgttgagctttacctat
caagtggcgcgagggatggaatttttggcttccaaaaattgtgtccaccgggacctggct
gctcgcaacgtcctcctggcgcaagggaaaatcgtgaagatctgtgacttcggcctggcc
agggacatcatgcacgattcaaactacgtgtccaaaggcagcacctttctccccgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtct
tacggcattctgctctgggagatcttttcccttgggggcaccccgtaccctggcatgatg
gtggattccactttctacaacaagatcaagaacgggtaccggatggccaagcctgaccac
gccaccagcgaagtctatgaaatcatggtcaagtgctggcacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgttgccgggacaatataagaag
agctacgaaaagattcacctggacttcttgaagagcgaccaccctgccgtggcacgcatg
cgcgtggactcggacaacgcctacatcggcgtcacctacaaacacgaggaagacaagctg
aaggactgggaaggcagcctggacgagcagaggctgagtgcagacagcggctacatcatc
cctctgcccgacatcgaccctgttcctgaggaggaggacctgggcaagaggaacagacac
agctcacagacctcagaagagagcgccattgagacaggttccagcagctctaccttcgtc
aagagagaggatgaaaccatcgaggacatcgacatgatggatgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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