KEGG   Felis catus (domestic cat): 101090936
Entry
101090936         CDS       T02385                                 
Symbol
MGST2
Name
(RefSeq) microsomal glutathione S-transferase 2 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00480  Glutathione metabolism
fca00980  Metabolism of xenobiotics by cytochrome P450
fca00982  Drug metabolism - cytochrome P450
fca00983  Drug metabolism - other enzymes
fca01100  Metabolic pathways
fca01524  Platinum drug resistance
fca05200  Pathways in cancer
fca05204  Chemical carcinogenesis - DNA adducts
fca05207  Chemical carcinogenesis - receptor activation
fca05208  Chemical carcinogenesis - reactive oxygen species
fca05225  Hepatocellular carcinoma
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101090936 (MGST2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101090936 (MGST2)
   00982 Drug metabolism - cytochrome P450
    101090936 (MGST2)
   00983 Drug metabolism - other enzymes
    101090936 (MGST2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101090936 (MGST2)
   05204 Chemical carcinogenesis - DNA adducts
    101090936 (MGST2)
   05207 Chemical carcinogenesis - receptor activation
    101090936 (MGST2)
   05208 Chemical carcinogenesis - reactive oxygen species
    101090936 (MGST2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101090936 (MGST2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101090936 (MGST2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101090936 (MGST2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:fca02000]
    101090936 (MGST2)
Enzymes [BR:fca01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101090936 (MGST2)
Transporters [BR:fca02000]
 Other transporters
  Pores ion channels [TC:1]
   101090936 (MGST2)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 101090936
NCBI-ProteinID: XP_003985040
UniProt: M3X1T6
LinkDB
Position
B1:complement(86331184..86357653)
AA seq 146 aa
MAGHSILLAAVSVLSACQQSYFALHVGKARLKYKVTAPAVSGSPEFERIFRAQQNCVEFY
PIFLITLWMAGWYFNQVFATCLGLVYIYARHQYFWGYSEAAKKRITGFRLSLAILALLTV
LGTLGIANSFLDEYMDLNVAKKLRRF
NT seq 441 nt   +upstreamnt  +downstreamnt
atggctgggcattcaatcttgctggccgctgtctcagtcttgtccgcctgtcaacaaagt
tattttgctttgcatgtaggaaaggcaagattgaaatacaaagttacagccccagcagtc
tctgggtcaccagagtttgagagaatatttcgtgcacaacaaaactgtgtggagttttac
cccatatttctgattacattgtggatggctggatggtatttcaatcaagtttttgctacc
tgtctgggtcttgtgtacatatatgcccgtcaccagtatttctggggatattcagaagca
gctaaaaaaaggatcaccgggttccggctgagtctggcgattctggccttgctgacagtc
ctgggcaccctggggattgcaaacagctttctggatgaatacatggacctcaatgtcgcc
aagaaactgagacgcttctaa

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