Felis catus (domestic cat): 101091260
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Entry
101091260 CDS
T02385
Symbol
KEAP1
Name
(RefSeq) kelch-like ECH-associated protein 1
KO
K10456
kelch-like protein 19
Organism
fca
Felis catus (domestic cat)
Pathway
fca04120
Ubiquitin mediated proteolysis
fca05012
Parkinson disease
fca05200
Pathways in cancer
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05225
Hepatocellular carcinoma
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101091260 (KEAP1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101091260 (KEAP1)
05208 Chemical carcinogenesis - reactive oxygen species
101091260 (KEAP1)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101091260 (KEAP1)
09164 Neurodegenerative disease
05012 Parkinson disease
101091260 (KEAP1)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
101091260 (KEAP1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
fca04121
]
101091260 (KEAP1)
Ubiquitin system [BR:
fca04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
Cul3 complex
Adoptor and target recognizing subunit (BTB)
101091260 (KEAP1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kelch_1
Kelch_6
Kelch_3
Kelch_2
BACK
Kelch_KLHDC2_KLHL20_DRC7
BTB
Kelch_4
Beta-prop_ATRN-LZTR1
BTB_KLHL33
NANM
Motif
Other DBs
NCBI-GeneID:
101091260
NCBI-ProteinID:
XP_023101067
UniProt:
M3WH36
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Position
A2:complement(7906682..7915465)
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AA seq
624 aa
AA seq
DB search
MQPEPRPSGAGARTRFLPLRSQRPEGAGDAVMYASTECKAEVTPSQHGNRTFSYTLEDHT
KQAFGIMNELRLSQQLCDVTLQVKYEDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGM
EVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLD
PSNAIGIANFAEQIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVR
CESEVFHACIDWVKYDCEQRRFYVQALLRAVRCHSLTPRFLQMQLQKCEILQADSRCKDY
LVKIFQELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQV
PRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGV
IDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDG
TNRLNSAECYYPERNEWRMIAPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVE
TETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTHMTSG
RSGVGVAVTMEPCRKQIDQQNCTC
NT seq
1875 nt
NT seq
+upstream
nt +downstream
nt
atgcagccggaaccgaggcctagcggggctggggcccgcacccgattccttcccctgagg
tcacagcgccccgagggggcaggggacgcggtgatgtacgcctccaccgagtgcaaagcc
gaggtgacgccctcccagcacggcaaccgcaccttcagctacacgctagaggaccacacc
aagcaggcctttggcatcatgaacgagctgcggctcagccagcagctgtgtgacgtcaca
ctgcaggtcaaatacgaggacgcgccggccgcccagttcatggctcacaaggtggtgctg
gcctcatctagccctgtcttcaaggccatgttcaccaacgggctgcgggagcagggcatg
gaggtggtgtccattgagggcatccaccccaaggtcatggagcgcctaattgagtttgcc
tacacggcctccatctccatgggtgagaagtgcgtgctccacgtgatgaacggcgccgtc
atgtaccagatcgacagtgtcgtccgcgcctgcagcgacttcctggtgcagcagctggac
cccagcaacgccattggcattgccaacttcgccgaacagatcggctgtgccgagctgcac
cagcgagcccgcgagtacatctacatgcacttcggagaggtggccaagcaagaggagttc
ttcaacctgtcccactgccagctggtgactctcatcagccgagacgatctgaacgtgcgc
tgcgagtccgaggtcttccacgcctgtatcgactgggtcaagtacgactgcgagcagcgg
cggttctacgtgcaggcgctgctcagggctgtgcgatgccactcgctgacaccccgcttc
ctgcagatgcagctgcagaagtgcgagatcttgcaggcggactcccgctgcaaggactac
ctggtcaagatcttccaggagctgaccttgcacaagcccacgcaggtgatgccctgccgg
gcgcccaaagtgggccggctcatctacaccgccggcggctacttccgccagtcgctcagc
tacctggaggcctacaaccccagcgatggcacttggctccgactggcggacctgcaggtg
cctcggagcggcctggcgggctgcgtcgtgggcgggctgctgtatgccgtgggcggccgg
aacaactcgcccgacggcaacaccgactccagtgccctggactgctataaccccatgacc
aaccagtggtcaccctgtgcccccatgagcgtgccgcgcaatcggattggggttggggtc
atcgacgggcacatctatgccgtgggtggctcccacggctgcatccaccacaacagtgtg
gagaggtatgagccagagcgggacgagtggcacctggtggccccaatgctgactcgaagg
atcggggtgggagtggctgtcctcaaccgtttgctctatgccgtcgggggctttgacggc
acaaaccgcctcaactcagccgaatgttactacccagagagaaacgagtggcggatgatc
gcacccatgaacaccatccgaagtggggcaggagtctgtgtcttgcacaactgtatctat
gctgcggggggctacgatggtcaggaccagctgaacagcgtggagcgctatgatgtggag
acagaaacgtggacttttgtagctcccatgaagcatcggcgaagtgccctggggattact
gtgcaccagggaagaatctacgttctgggaggctacgacggtcacacgttcctggacagt
gtggagtgttatgacccagacaccgacacctggagcgaggtgacccacatgacatccggc
cggagcggcgtgggtgtcgccgtcaccatggaaccctgccgaaagcagatcgaccagcag
aactgtacctgttga
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