Felis catus (domestic cat): 101091290
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Entry
101091290 CDS
T02385
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00260
Glycine, serine and threonine metabolism
fca00630
Glyoxylate and dicarboxylate metabolism
fca00670
One carbon pool by folate
fca01100
Metabolic pathways
fca01200
Carbon metabolism
fca01230
Biosynthesis of amino acids
fca01240
Biosynthesis of cofactors
fca01523
Antifolate resistance
fca04981
Folate transport and metabolism
Module
fca_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101091290 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101091290 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101091290 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101091290 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101091290 (SHMT2)
Enzymes [BR:
fca01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101091290 (SHMT2)
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Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
101091290
NCBI-ProteinID:
XP_003988982
UniProt:
M3VU92
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All DBs
Position
B4:83576653..83582207
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AA seq
504 aa
AA seq
DB search
MLPFSLLWATRPLQRCGHLGRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGMQAVD
PKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYALQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDTETSH
RLADLRQRVEQFARAFPMPGFDER
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcgactcggcctctgcagagatgtggtcatctgggc
aggatggccatacggtgccaacacagtgaggtggcccagacccagactggagaagcaacc
aggggctggacaggccaagagagtctgtcagacagtgaccctgagatgtgggagctgctg
cagagagagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccttggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattatggaggagcagaggtagtggatgaaattgagctgctgtgtcag
cgccgggccttggaagcctttgacctggatcctgcacagtggggagtcaatgtccagcca
tactcaggctctccggctaatctggcggcctatacagcccttctgcagcctcatgaccga
atcatggggctggacttgcctgatgggggccatcttactcacggctacatgtctgatgtc
aagcggatctcggccacatccattttctttgagtctatgccctataagttaaatcccaaa
actggcctcatcgactatgaccagctggcactgaccgctcggcttttccgaccgcggctc
attatagctggtaccagtgcctacgctcgcctcattgactacgcccgcatgagagaggtg
tgtgatgaggtcaaggcacacctcctggcagacatggcccacatcagtggcctggtggct
gccaaggtgatcccctcacctttcaagcacgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaggggatgcaggctgtggac
cccaagaccggccgggagatcccttacacatttgaggaccgaatcaactttgctgtgttc
ccatccctgcagggggggccccacaaccatgccattgctgcagtggctgtggccttaaag
caggcctgcacccccatgttccgggagtacgccctgcaggttctgaagaatgctcgggcc
atggccgatgccctgctagagcgaggctattcgctcgtatctggtggcactgacaatcac
ctagtgctggtggacctgcggcccaagggcctggatggagctcgggctgagcgggtgctg
gaacttgtatccattacagccaacaagaacacctgtcccggagaccgaagtgccatcaca
cctgggggcctgcggctcggggccccagccttgacctctcgacagttccgtgaggatgac
ttccggagagttgtagactttatagatgaaggggtcaacatcggcttggaggtgaagagc
aaaactgccaaactccaggatttcaaatccttcctgctcaaggacacagaaaccagtcat
cggctggccgacctccggcaaagggtggaacagtttgccagggccttccccatgcctggc
tttgatgagcgctga
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