Felis catus (domestic cat): 101092407 Help Entry 101092407         CDS       T02385                                  Symbol NF1 Name (RefSeq) neurofibromin isoform X1   KO K08052   neurofibromin 1 Organism fca  Felis catus (domestic cat) Pathway fca01521   EGFR tyrosine kinase inhibitor resistance fca04010   MAPK signaling pathway fca04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101092407 (NF1)    04014 Ras signaling pathway     101092407 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101092407 (NF1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  101092407 NCBI-ProteinID:  XP_023099294 LinkDB All DBs Position E1:19249552..19498473 Genome browser AA seq 2884 aa AA seqDB search MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN STFKHGLGTASALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKE KVTSLKFKEKPTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLV QLVPQSHMPEIAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQM LSSTEILKWLREILICRNKFLLKNKQADRSSCHFLFLYGVGCDVPSSGATSQMSMDHEEL IRTCTPGASLRKGKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMS CFRHLCEEADIRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEH PTAGNTEAWEDTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDL SDTDSLQEWINMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNAD TPVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQ GQVLLTDTNTQFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHA IQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDL DQASMEAVVSLLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTG GRKRGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQ QGTEFDTLAETVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFD SRHLLYQLLWNMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIV ITSSDWQHVSFEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCL YQATCHSLLNKATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILD KKPPPRIERGLKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPT SDAVNHSLSFISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGP PEHKPVADTHWSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYY VARRFKTGQINGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPG FAYDNVSAVYIYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPA ATLALEEDLKVFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEI EEICLVDENQFTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPK DVPGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFI VSISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKR QRVTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKA EVMADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLML SFNNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQV LRLSLTEFSLPKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEA LLEIMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQII RILSKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEV NLYSAGTALLEQNLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNF ALVGHLLKGYRHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEE VRSRCSLKHRKSLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAATY PAVGQTSPRARKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPK MRRVAETDYEMETQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVK YTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSV VYHEESPPQYQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDE ETSEESLLTPTSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPEDSVSPSVIPRPASVS FGSSLGCRCYSPTADLLRIDKENVELSPTSGHCNSGRTRHGSASQVQKQRSAGSFKRNSI KKIV NT seq 8655 nt NT seq  +upstreamnt  +downstreamnt atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag cttccaataaaaacaggacagcagaacacgcataccaaagtcagtactgaacacaacaag gaatgtcttattaatatttccaaatacaagttttctttggttatcagcggcctcaccact atcttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttgtat ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac acaatgagattagatgaaacgatgctggtcaaacagttgctgccagaaatctgccatttt cttcacacctgtcgtgaaggaaaccaacatgcagctgaacttcggaattctgcatctggg gttttattttctctcagctgcaacaacttcaatgcagtgtttagtcgcatctctaccagg ttacaggaattgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta cagtatatcaatgtggattgtgcaaaattaaaacgactcctaaaggaaacagcatttaaa tttaaagccctaaagaaggttgcacagttagcagttataaatagcctggaaaaagcattt tggaactgggtagaaaattatccagatgaatttacaaagctgtaccagattccacagact gatatggctgagtgtgcagaaaaactgtttgacttggtggatggttttgccgaaagcacc aagcgtaaagcagcggtttggccactgcaaatcattctccttatcttgtgtccagaaatc attcaggatatctccaaggatgtggttgatgaaaacaacatgaataagaagttgtttctg gacagcctacggaaagcacttgccggccatggaggaagcaggcagctgacggagagtgct gcaatagcctgtgtcaaactgtgcaaagcaagtacttatatcaactgggaagacaactct gtcattttcctcctagtccagtccatggtggttgatcttaagaacctgctttttaatcca agtaagccattctcaagaggcagtcagcccgcagatgtggatctgatgattgactgcctt gtctcttgctttcgtataagccctcacaacaaccaacactttaagatctgcctggctcag aattccccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat agcactttcaagcatggacttggcactgcttctgcgttggattggtggcctaagatcgat gctgtatattgtcactcagtcgagcttcgaaacatgtttggtgaaacgcttcataaagca gtgcagggttgtggcgcacacccagcaatacgaatggcaccgagtcttacatttaaagaa aaagtaacaagccttaaatttaaagaaaaacctacagacctggagacaagaagctataag tatcttctcctgtccatggtgaaactcattcatgcggatccaaagctcttgctttgtaat ccaaggaaacaggggcctgaaacccaaggcagtaccgcagaattaattacagggctcgtc cagctggtccctcagtcacacatgccagagatcgcacaggaggcaatggaggctctgctg gttcttcatcagttagatagcattgatttgtggaatcctgatgctcctgtggaaacattt tgggaaattagctctcaaatgcttttttacatctgcaagaaattaactagccatcaaatg cttagtagcacagaaattctcaaatggttgcgggaaattttgatctgcaggaataaattt cttcttaaaaataagcaggcagatagaagttcctgtcactttctcttcctttacggggta ggatgtgatgttccttcgagtggagctaccagtcagatgtccatggatcatgaagaatta atacgtacttgtacgcctggagcctctcttcggaagggaaaaggaaactcatccatggat agtgcagcagggtgcagcggcacaccgccgatatgccgacaggctcagaccaaactcgaa gtggccctgtacatgtttctgtggagccctgacactgaagctgttctggttgccatgtcc tgtttccgccacctctgtgaggaggcagacatccggtgtggggtggatgaagtgtcggtg cacaacttcttgcccaactataacacattcatggaatttgcctctgtcagcaatatgatg tcaacaggaagagcagcacttcagaaaagagtgatggcactactcaggcgcatcgagcac cccacggcaggaaacacagaggcttgggaagatacacatgcaaagtgggaacaagccaca aaactaatcctcaactatccaaaagctaaaatggaagatggccaggctgctgaaagcctt cacaagaccattgttaagaggcgaatgtctcatgtgagtggaggaggatccatagatttg tctgacacggactccctacaggaatggatcaacatgactggcttcctttgcgcccttggg ggagtgtgcctgcagcaaagaagcaactctggcttggcaacctatagcccccctatgggc ccagtcagtgaacgcaagggttccatgatttcggtgatgtcctcggagggaaatgcagat acacctgtcagcaaatttatggatcggctgttatccttaatggtgtgtaaccatgagaaa gtgggacttcaaatacggaccaacgttaaggatctggtgggtctagaattgagtcctgct ctttatccaatgctatttaacaaattgaagaataccatcagcaagttttttgactcgcaa ggacaggttttattgaccgacaccaatactcagtttgtggagcaaaccatagctataatg aagaacttactagataatcataccgaaggcagctccgaacatctggggcaagctagcatt gaaacaatgatgttaaatctagtcagatacgttcgagtgcttgggaacatggtccatgca attcaaataaaaacgaaactgtgtcagttagtcgaggtaatgatggcaaggagagatgac ctctcattttgtcaagagatgaaatttaggaataagatggtagaatacctgacagactgg gtcatgggaacatcaaaccaagcagcagatgatgatgtaaaatgtcttacaagagacttg gaccaggcgagcatggaagccgttgtttcactcctggctggtcttccactgcagcctgag gaaggagatggtgtggaattgatggaagccaaatcacagttatttctgaagtatttcaca ttgtttatgaaccttttgaatgactgtagtgaagttgaagatgaaaatgcacaaacaggt ggcaggaaacgtggcatgtcccggaggctggcatcactgaggcactgcacagtccttgca atgtccaacttactcaatgctaatgtggacagtggcctcatgcactccataggtttaggt tatcacaaagatcttcagacaagagctacatttatggaagttctgacaaaaatcctccag caaggcacagaatttgacacgcttgcagaaacggtgctggccgaccggtttgagaggctg gtggagttggtcacaatgatgggagaccagggagagctaccaatagccatggctttggcc aacgtggtcccgtgttctcagtgggatgaactagctcgagttctagtgactctgtttgat tctcggcatttgctctaccaactgctctggaacatgttttctaaggaagtagaattggca gactccatgcagactcttttccgaggaaacagcttagccagtaaaataatgaccttctgt ttcaaggtatatggtgctacctacctacaaaaactcctggatccgttattacgaatcgtg atcacatcctctgattggcaacatgttagctttgaagtggatcctaccaggttagaacaa tcagagagccttgaggaaaaccaacggaaccttctgcagatgactgaaaagttcttccat gccatcatcagttcctcctcagaattcccccctcagcttcgaagtgtgtgccactgttta taccaggcaacttgccactccctactgaataaagctacagtaaaagaaaaaaaggaaaac aaaaaatcagtggttagccagcgtttccctcagaacagcatcggtgcggtgggaagtgcc atgttcctcagatttatcaatcctgccattgtctcaccgtatgaagcagggattttagat aaaaagccaccacctagaattgaaaggggcttgaagttaatgtcaaagatacttcagagc attgccaatcatgttctcttcacaaaagaagagcatatgcggccttttaatgattttgtg aaaagcaactttgatgcagcgcggaggtttttccttgatatagcatctgattgtcctacc agtgatgcagtaaatcatagtctctccttcatcagtgatggcaatgtgcttgctttacat cgtctactctggaacaatcaagagaaaattggccagtatctttccagtaacagggatcac aaagctgttggaagacgaccttttgataagatggcaacacttcttgcgtacttgggtcct ccagagcacaaacctgtggccgatacacattggtccagccttaaccttaccagttcaaag tttgaggaatttatgactaggcatcaagtacatgaaaaagaagagttcaaggctttgaaa acattaagtattttctaccaagctgggacttccaaagctgggaatcctatattttattat gttgcacggaggtttaaaactggccaaatcaatggcgatttgctgatataccacgtcttg ctgactttaaagccatattatgcaaagccatatgaaattgtagtggaccttacccatact gggcctagcaatcgctttaaaacggactttctctccaagtggtttgttgtttttcctggc tttgcttatgacaatgtctctgcagtctatatctataactgcaactcctgggtcagagag tataccaagtatcacgaacggctactgactggcctcaaaggcagcaagaggctcattttc atcgactgtcctgggaaactggctgagcacatagagcatgaacaacagaaactgcctgct gccacactggctttagaagaggacctgaaggtattccacaatgctctcaagctagctcac aaagacaccaaggtttctattaaagttggttctactgctgttcaagtaacctcagcagag cgaacgaaagtcctaggacagtcggtctttctaaatgatatctattatgcttcggaaatt gaagagatctgcctggtggatgagaaccagtttaccttaaccattgcaaaccagggcaca ccgctcaccttcatgcaccaggagtgcgaagccatcgtccagtctatcattcacatccgg acacgctgggagctgtcgcagcccgactccatcccccagcacaccaagattcggccaaaa gacgtccctgggacactactcaatattgcattacttaatttaggcagttccgaccctagt ttacggtcagctgcctataatcttctctgtgccttaacttgtacctttaatttaaaaatc gagggccagctactagagacgtcaggtttatgcatccctgccaacaacaccctctttatt gtctctattagtaagacactggcggccaatgagccacatctcaccttagaatttttggaa gagtgtatttctggatttagcaaatctagtattgaattgaaacacctttgtttggaatac atgactccatggctgtcaaacctggtccgtttttgtaagcacaatgatgatgccaaacga caaagagttaccgccattctcgataagctgataacaatgaccataaatgagaaacagatg tacccatctattcaagccaaaatatgggggagccttgggcagattacagatctccttgac gttgtactagacagtttcatcaaaaccagtgcgacaggtggcttgggatcaataaaagcc gaggtgatggcagatactgccgtagctttggcttctggaaatgtgaaattggtttccagc aaggttattggaaggatgtgcaaaataattgacaagacatgcttgtctccaactcctacc ttagaacagcatctcatgtgggacgacattgccatcctcgcacgctacatgctgatgctg tccttcaacaattcccttgacgtggcagctcatctcccctacctcttccacgttgttact ttcttagtagccacggggccgctctcccttagagcttccacacacggattggtcattaat atcattcactctctgtgtacttgttcacagctgcattttagtgaagagaccaagcaagtt ttgagactcagtttgacagagttctcattacccaagttttacttgctgtttggcattagc aaagtcaagtcagctgcggtcattgccttccgctccagttaccgggacaggtcgttctct cctggctcctatgagagggagacttttgctttgacatccttggaaacagtcacagaagct ttgttggagataatggaggcatgtatgagagatattccaacatgcaagtggctggaccag tggacggaactagctcaaagattcgcattccagtataatccatccctgcaaccgagagct cttgttgtctttggctgtattagcaagcgagtgtctcatgggcagataaagcagattatc cgtattcttagcaaggcacttgaaagttgcttaaaaggacctgatacttacaacagtcaa gttctgatagaagccacagtaatagcgctaaccaaattacagccgctcctcaataaggac tcccctctgcacaaagccctcttttgggtagctgtggctgtgctacagctcgatgaggtc aacttgtattcagcaggcaccgcccttcttgaacaaaacctgcacaccttagacagtctg cggatattcaatgacaagagtccagaggaagtatttatggcaatccggaaccctctggaa tggcactgcaagcagatggatcattttgttggactcaatttcaactctaactttaacttc gcgctggttggacacctcttaaaagggtacaggcatccttcacctgccattgttgcaaga acggtcagaattctgcatacactactgactctggtcaacaaacatagaaactgtgacaaa tttgaggtgaacacacagagcgtggcttacttggcagccttactcacagtgtctgaggag gttcgaagtcgctgtagcctaaaacatagaaagtctcttcttcttactgatatttcaatg gaaaatgttcctatggatacatatcccatccatcatggcgaccccagctataggacgcta aaggagaaccagccgtggtcatctcccaaaggttctgaggggtaccttgcagccacctat ccagccgtgggccagaccagtccccgggccaggaagtccatgagcttggacatggggcag ccttctcaggccaacacgaagaagttgctgggaacaaggaaaagttttgatcacttgata tcagacacaaaggctcctaaaaggcaagaaatggaatcagggatcacaacaccccccaaa atgaggagagtagcagaaactgattatgaaatggaaactcagcggatttcctcatcacaa caacacccacatttgcgtaaagtttcggtgtctgaatcaaatgttctcttggatgaagaa gtacttactgatccaaagatccaagcgcttcttctgaccgttctggctacgctggtaaaa tataccacggatgagtttgatcagcgaattctttatgaatacttagcggaagccagtgtt gttttccccaaggtttttccagtcgtacacaatttgttggactctaagatcaacaccctg ttgtcattgtgccaagatccaaatttgttaaatccaattcatggaattgtgcagagtgtg gtgtaccatgaggaatctccaccacagtaccagacatcgtacctgcaaagttttggtttt aatggcttgtggcggtttgcaggacccttttcaaagcaaacccaaatcccagactatgct gagcttattgttaagtttcttgatgccttgattgacacgtatttgcctggaattgatgaa gaaaccagtgaggagtccctcctgacacccacttctccttatcctcctgcagtgcagagc cagcttagtatcactgctaaccttaacctttctaattccatgacctcactcgcaacttcc cagcattccccagaggacagtgtttctccaagtgtgattcctagaccagcatcagtgtca tttgggagctcgctaggatgcaggtgctacagtcccactgcagacctcctacggatcgac aaggagaacgttgaactctcccccacctctggccactgtaacagtggacgcactcgccat ggatccgcaagccaggtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcatt aagaagatcgtgtga

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