Felis catus (domestic cat): 101093692 Help Entry 101093692         CDS       T02385                                  Symbol SPG11 Name (RefSeq) spatacsin isoform X1   KO K19026   spatacsin Organism fca  Felis catus (domestic cat) Pathway fca04142   Lysosome fca05014   Amyotrophic lateral sclerosis fca05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:fca00001]  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     101093692 (SPG11)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     101093692 (SPG11)    05022 Pathways of neurodegeneration - multiple diseases     101093692 (SPG11)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:fca03400]     101093692 (SPG11) DNA repair and recombination proteins [BR:fca03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      101093692 (SPG11) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Spatacsin_C Motif Other DBs NCBI-GeneID:  101093692 NCBI-ProteinID:  XP_003987258 UniProt:  A0ABI8A2U7 LinkDB All DBs Position B3:58791365..58879666 Genome browser AA seq 2444 aa AA seqDB search MAAEEAAGRAASWGSCSSKAMERVLPMLLVPVPAEATRRLGSRAQLHREQEVLGSLTAAG SLQVLSLAPSGRSRGACCLNGPFRHFVWDQSHKSSSPTDKPKLLALSENYELFIYEFNLK DGRCDATILYSCSEETLQKLIEDQNISVSILSLRILSFHDNTSLLLINKCIIVHLIFPER DAEVGVCSCFTLPLPAQAVDRIIDTQLCRGILFVLSSLGWIYIFDTVDGRHVAHVDLALH QEDMCDEQQQEPAKVSSFTSLKVSQDLDVVVIISSSNSAIALNLNLYFRQHPGHLLCERT QEDMPVEGPKGIDEDDPVNSDYNMKLTKFSFQVDRSWKAQLSSLNETIKSSNLEVSYCAP WFQNILHLESPESGNPSTSMPGWAFIPPDIMHNQYNFPQKDHAKTRDPGRSWKTMHIHEQ EEPIELKCMSVTGFSALFTWAVERTGCTIVLWDLETQGLQCFSLGQKCIPIDSCGDQQLC LVLTENGLSLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQ LDTVDFFLKSKENLLNPSSKSSVPDQLDHFPSHLYLKNVEKLTPALDLLCSAIRESDSET QSKHFSEQLLNLTLSFLNKQIKELFLHNEELDEHLQQGVNILTSYINELRTFMIKFPWKI IDTVDEYDVNENVPKVRESDIWKKLSVEEVIADAILNNRIPEAQAFFRINSHSAQRLEEL IRIGLNLVFDNLKKNNIKEASELLKNMGFDVKDQLLKICFYTTDKDIRDFLVEILKEKNY FSENEKRTIDFVHQVEKFYSGHFQENVQIQSFARYRMKEQDFFKHKSVLDSLLKHDPKDK FNKQDHRVVLNWAQWWNQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWSSIILWIG EFQTQNSCASLQQNRWPLLTVDVIDQNTCCNNYMRNEILDKLARSGIFLQSELEDFELFL LRLNRIGGVMQDTLPVQNYRSKEGWDFHSHFILYCLEHSLQYLLYVYLDHYKLNPSNCPF LEKSELYEAHPWFEFLVQCRQVSSNLTDPKLIFQASLANAQILIPSNQASVSSMLLEGHT LLALATTMYAPGGVSQVVQNDENETCLKKVDPQLLKMALTPYPKLKTALFPQYTASNVLP PDITLYHLMQSLLPFDPSRLFGWQSANTLAIGDAGSHLPHFSSPDLVNKYAIVERLNFAY YLQHGRPSFAFGTFLVQELTKSKTPKQLVQQVGDEAYVLGLSSFYIPSIAAACVCFLELL GLDSLKLRVDMKVANIILSYKCRNEDAQYSCVRESLAEKLSKLAMGEKATIEELLTLLEE GIWSSIQQQEINRISSESSSQWALAVQFCRIHNVKLSTSYLRECAKANDWLQFIIHSQLH NYHPEEVKSLLQYFSPVLEDHLRLAFENLPLVSNSRMDSDQVCNRSPQEFQGNKEEMTDL FEVLLQCSEEPNSGSWLLAEAVKQQAPILSVLASCLQGASTIPCLCVWIITSVEESVAAE ATGHIQGSVEGHTWELQDLSVIWKTLLTRRKSKTLIRGFHLFLKDSPLLLMMEIYELCMF FKNYKEAEVKLLEFEKSFETVETTATRVHATIPAAWLKEQVCFLLKLMLQQCGTQYELGK LLQLFVGIEHLFCDGPDVKKLCVLSKILKDTSIAINPVVISSYSPENFQHECRSILEKLE TEGQFALARRVAELAELPVDNLVIEEITQEMQTLKHIDQWSLKQARIGFWKKCHENFKRN SISSKAASSFFSAQAPEACECPAEGALSSIEEAHLLLTLAAHWLAQEGLVPVDELEELEK RIWLCRIAQHTLRENPEETEPRFSQQISTSGELSFESVASEFSISMLATLNTSKYLELNG LPSKETCDNTLGRKEQESLNFLIGRLLDDGCVHEASRICRYFHFYNQDVALVLHCRALAS GEASVGDLHPEVHAVLQSAELPEEEEPGMPLRKARSTSSLDSQSLVMLPPRDEVVTNLET LTSKCLHGKNYCRQVLCLYELAKELGCSYADVAARDGEAMLRTILASQRPDRCKRAQAFI STQGLEPDTVAELVAEEVTRELLTPSEGTGLKQMFTPAEESQTFLQLTTLCQDRTLVGMK LLDKISSVPHGELSCTTELLILAHHCFTLTCHMEGISRVLQAARLLTDKHLAPSEEYGLM VRLLTGIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHN MIALCFSMCREIGENHEAAACIQLKLIESQPWEDRLKDGHHLKQLLLKALTLMLDAAESY AKDSCVRQALHCHRLTKLITLQIHFLNTGQNTMLINLGRHRLMDCITALPRFYQASIVAE AYDFVPDWAEILYQQVIVKGDFNYLEEFKQQRLLRSSVFEEISKKYKQHQPTDTAVKNLK KLLTYCEDVYLYYKLAYEHKFYDIVNMLLKDPQTGCCLKDMLAG NT seq 7335 nt NT seq  +upstreamnt  +downstreamnt atggctgcagaagaagcagccggcagggctgccagctggggcagttgcagctctaaagcc atggaacgggttctacctatgttgttggtgccagtcccagcggaggcaacacggcggctg ggatcccgggcacagttgcacagagagcaggaggttctggggagcctaacagctgcaggc agcctgcaagtgctttccttggcgccgagcggccggagtcgaggtgcctgctgcctcaat ggtccctttcggcactttgtatgggaccagtctcataagagcagctcaccaacagacaag cccaaactgcttgctcttagtgagaattatgaactgtttatctatgaatttaatttgaaa gatggaagatgcgatgcaaccattttgtatagctgtagtgaggagacattgcaaaagctc attgaagatcaaaatatcagtgtttccatattgtctttgagaattctgtcatttcacgat aacacttcactattgctcatcaacaaatgtatcatcgtacaccttatatttcctgaaaga gatgctgaggttggagtatgcagctgttttacattacccttgcctgcacaggcagtggac aggattattgacacgcagctctgcagaggaattctctttgttttgagtagtttaggctgg atctacatttttgacactgtggatggtagacatgtagctcatgtggatttagcacttcac caagaagatatgtgtgatgagcagcaacaggagccagccaaggtttcttcatttacttcg ctgaaagtgtctcaagacctagatgttgtggtgattatcagctcttccaactctgcaatt gctcttaacttaaatttgtatttcaggcaacacccaggacacctactatgtgaaagaact caagaagacatgcctgttgaaggccctaaggggatagatgaagatgatcctgttaattct gactacaacatgaaactgaccaagttttcctttcaagttgataggtcttggaaagcccag ctatcatcattgaatgaaacaataaagagttccaacctggaggtttcctattgtgctccg tggttccagaatattttgcatttggagtctcctgaatctggtaaccccagtaccagtatg ccaggctgggccttcattccaccagacataatgcacaaccagtataattttccacagaaa gatcatgccaagaccagggatccaggaagatcatggaaaacaatgcacattcatgaacaa gaggaacctattgagcttaaatgtatgtctgtgacaggattcagtgcactgtttacttgg gcagtggaaaggacgggctgcaccattgtcctttgggatttggagacccagggcctgcag tgcttttcccttggccaaaagtgtattcctatagacagttgtggagaccagcaactctgc cttgttttgacagaaaatggactctctctgattttgtttggattgactcaggaggagttt ttaaatagactaatgatccatggaagtgccagtactgtggactctctttgccatctcaat ggttgggggagatgctcaatccccatccatgcactggaggctgggatagaaaatcgtcag ctggacacagtagatttctttttgaagagcaaagaaaatcttttgaatccatcctcaaaa tcttctgtacctgatcagttggatcattttccatctcatttatatttaaaaaatgtggaa aagctgacaccagccttggatttactttgctcagcaattagagaaagtgattctgaaacc caaagcaaacacttttcagaacagttgcttaatcttacactgtcttttcttaacaaacaa ataaaggagctttttcttcacaatgaagaactagatgaacatctacagcagggagtgaac attttgaccagctacattaatgaacttcgaaccttcatgataaagtttccttggaagata atagataccgtagatgaatatgatgtaaatgaaaatgtccccaaagtaagagaaagcgat atatggaagaaactcagtgttgaggaagttattgccgatgctattttgaacaacagaata ccagaggcacaggctttcttcaggattaacagtcattctgctcaaagacttgaggagctt attagaataggcctaaatttggtctttgacaatttgaaaaagaacaacataaaggaagcc tctgaacttttgaagaacatgggctttgatgtaaaagaccagttgctcaagatctgcttc tatacaactgataaagatatacgggactttttggttgaaattttaaaagaaaaaaattat ttttctgaaaatgaaaagagaactatagacttcgtgcatcaagttgagaagttttattca ggacattttcaagaaaatgtgcagatccagtcctttgccaggtataggatgaaggaacag gattttttcaagcacaaatctgttttggactcactcctgaaacatgatcctaaagataaa tttaacaaacaggaccacagagttgtgttaaattgggctcagtggtggaatcaactaaca caagaatccatccttctccccaggataagtccagaagagtacaaatcatattctcccgaa gccctctggagatacctcacagctcgccatgattggtcaagcattatcttgtggattgga gaatttcagacccagaacagttgtgcttcacttcagcagaacagatggccccttctgact gttgatgttattgatcagaatacttgctgcaacaactacatgaggaatgaaattttagat aagctggccaggagtgggatttttcttcagtctgaactagaagactttgaactcttcctc ctaagactgaaccgaattggaggtgtgatgcaagatactctacctgttcaaaactacagg tccaaagaaggttgggatttccattctcacttcattctctattgtttggaacacagtctg cagtatcttctctatgtctatcttgaccattacaaacttaatccttcaaattgtcccttt ttggaaaaaagtgaattatatgaagctcacccttggtttgaatttttagttcagtgtcga caagtttccagtaatttaacagatcccaaattgatcttccaggctagccttgcaaatgct cagatactgattcccagcaaccaggccagtgtaagcagtatgctgttggaaggacatact ctcctggcccttgctactacaatgtatgcccctgggggtgtcagccaggttgttcagaat gatgaaaatgagacctgtttgaagaaagtagatccccagttactgaagatggcattaact ccttatcccaagctaaaaactgctctattcccacagtataccgcctctaatgtcctgcca cctgatattacactttaccaccttatgcagtcattattgccctttgatcctagcagattg tttggctggcaatctgccaacacactggctataggagatgcagggagtcatctcccgcat ttttctagccctgacctggttaataagtatgctatagtggaacgtctgaattttgcttat tatttacaacatggacggccttcgtttgcatttggtacttttctggtccaggaattaacc aagagcaagactcccaagcagctggtccagcaagtaggcgatgaggcctatgttttagga ctctcctccttctacataccttcaatagcagctgcgtgtgtttgtttcttagaactgctt ggcctcgacagcctaaagctcagagttgatatgaaagtggccaatataattttgagctac aagtgtagaaatgaagatgctcagtacagctgtgtcagagagtctctagctgaaaaacta tctaaactggctatgggtgaaaaggcaaccatagaagaattgcttactcttttagaagaa ggtatatggagcagcattcagcagcaggaaataaataggatatctagtgaatctagcagc cagtgggcattagcggtacagttctgcaggatccacaatgtgaaactgagcacatcttac ctcagagaatgtgccaaagcaaatgattggttacagttcattattcacagtcaactccat aactatcacccagaggaggtgaaatctcttcttcagtatttcagtcctgtccttgaagac cacttaagattggcttttgagaacttgcccttagtgtccaactccaggatggacagtgat caagtctgcaacaggtccccccaggaattccagggaaacaaagaagagatgactgatctc tttgaagttctgctccagtgctcggaggagccaaactccgggtcctggctcctagctgaa gctgtgaaacaacaggcccctatccttagtgtcttggcctcatgtctccagggtgccagt actattccttgtctctgtgtttggatcatcacatctgtggaggagagtgttgcagccgaa gcaacaggacacattcagggctcagtggagggccacacgtgggagcttcaagacctctca gtcatctggaaaacattattaacaaggcggaagagcaaaactctcatcagaggtttccac cttttcttgaaggattccccactactgttgatgatggagatatatgaactatgtatgttc tttaagaattataaggaagctgaagttaaacttctggagttcgaaaaaagctttgagact gttgaaacaacagccacaagggtccatgctaccatccctgctgcatggctgaaggagcag gtgtgttttcttttgaagcttatgctgcagcagtgtgggacccagtatgaactggggaag cttttacagctatttgttggaatagaacatctcttctgtgatggtccagatgtgaagaag ctctgtgtccttagcaaaattttgaaggatacatccatagccattaatcctgtagttatt agcagctacagccctgagaattttcagcatgaatgcagatctattttggaaaaactggag acagagggacagtttgctttggccaggagggtagcagaattagctgagctacctgtggac aacttggttattgaagagataacacaggaaatgcagaccttaaaacacattgaccagtgg tccctgaaacaagcaagaattggcttctggaaaaaatgtcacgagaattttaagagaaat tccatttcaagcaaagcagcttcctcctttttctcagcccaggcccctgaggcatgtgag tgcccagctgagggggcactgagcagcattgaggaggcccatctgctgctgacactggct gcacactggcttgctcaggagggcctggtgcccgtggacgagctggaggagctggagaag cggatctggctctgccgcatcgcccagcacaccctcagggaaaacccagaggaaacagag cccaggttttctcaacagatctcaactagtggggaactttcctttgaaagcgtagcgagt gagttttcaatctccatgttggccactctgaacacatcaaaatacttagaacttaatggc cttccatccaaagagacttgtgataacacactgggccggaaggagcaggaatcgctgaac ttcctgatcgggcgcctattggacgacggctgtgtgcatgaagcaagtagaatatgtcgg tattttcatttctataaccaagatgttgccttggtgttgcactgcagagcactggcttca ggggaagctagtgtgggtgacctgcacccagaagtccatgctgtcctgcaaagtgctgag ctgcctgaggaggaagaacctggcatgccactaaggaaagcccggagcacttcaagtttg gatagtcagtcacttgtgatgctgccccccagggatgaagtagtgactaatctggaaact ctgacaagcaaatgcctccatgggaagaactactgtcggcaggtcctgtgtctgtatgaa cttgccaaggagttgggctgttcctacgcagatgtggccgctcgggacggtgaggccatg ctcaggacgatcttggcctctcagcggcccgaccgatgcaagcgggcccaggctttcatc agcacccagggcctcgagccagacacagtggctgaacttgtggccgaagaggtaacccgg gagctgctgaccccatcggagggaacaggacttaagcagatgttcaccccagcagaggaa agccagacatttcttcagctgaccactctgtgtcaagaccgcacgttggtaggcatgaag ctattagacaagatttcctccgttccccatggggagttgtcttgcaccacggagctgctg atcctggcccatcattgcttcacgctgacatgccacatggagggcatcagccgagtcctg caggctgcccggctgcttacagacaaacacttggcccccagtgaggagtatgggctgatg gtgcgcctgctcactggcattggaaggtacaatgagatgacctacatatttgatttgctg cataaaaagcactactttgaagtgctgatgaggaagaagttggatccgagtggtaccctg aagacagcactgctggactacatcaaacgctgtcgcccaggagacagtgagaagcacaac atgattgctctgtgcttcagcatgtgccgggagatcggggagaaccacgaggcagctgcc tgcatccaactgaaattgatcgagtctcagccctgggaggaccgcctcaaggatgggcac cacctgaagcagctgctgctgaaagccctgactctgatgttggatgcagcagagagttat gccaaggactcctgtgtgcgacaggccctgcactgtcaccggctcaccaagttgataaca ctgcagattcactttctgaacactggccagaacacaatgctcatcaacctgggccgccac aggctgatggactgcatcactgctctacctcggttctaccaggcttctattgtagctgag gcctatgactttgttcctgattgggctgaaattctataccaacaagtgattgttaaagga gactttaattacttggaagaatttaagcagcaaaggttattaagatctagtgtattcgaa gagatttcaaaaaaatacaaacagcatcagcctactgacacagctgtgaaaaacctgaag aagttactcacttattgtgaagatgtctacttgtattacaaacttgcatatgaacacaaa ttttatgacattgtaaatatgcttctgaaggaccctcaaactggctgctgtctaaaggac atgctagcaggttag

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