Felis catus (domestic cat): 101096463
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Entry
101096463 CDS
T02385
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial isoform X1
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00220
Arginine biosynthesis
fca00330
Arginine and proline metabolism
fca01100
Metabolic pathways
fca04020
Calcium signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04066
HIF-1 signaling pathway
fca04071
Sphingolipid signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04370
VEGF signaling pathway
fca04371
Apelin signaling pathway
fca04611
Platelet activation
fca04915
Estrogen signaling pathway
fca04921
Oxytocin signaling pathway
fca04926
Relaxin signaling pathway
fca04931
Insulin resistance
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca05415
Diabetic cardiomyopathy
fca05417
Lipid and atherosclerosis
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
101096463 (NOS3)
00330 Arginine and proline metabolism
101096463 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
101096463 (NOS3)
04371 Apelin signaling pathway
101096463 (NOS3)
04066 HIF-1 signaling pathway
101096463 (NOS3)
04020 Calcium signaling pathway
101096463 (NOS3)
04071 Sphingolipid signaling pathway
101096463 (NOS3)
04022 cGMP-PKG signaling pathway
101096463 (NOS3)
04151 PI3K-Akt signaling pathway
101096463 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101096463 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
101096463 (NOS3)
04921 Oxytocin signaling pathway
101096463 (NOS3)
04926 Relaxin signaling pathway
101096463 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101096463 (NOS3)
05418 Fluid shear stress and atherosclerosis
101096463 (NOS3)
05415 Diabetic cardiomyopathy
101096463 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
101096463 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
101096463 (NOS3)
Enzymes [BR:
fca01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
101096463 (NOS3)
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GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
101096463
NCBI-ProteinID:
XP_003983267
UniProt:
M3WID9
LinkDB
All DBs
Position
A2:163142295..163160428
Genome browser
AA seq
1203 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPTAEPGRAPAPAPPPPPAPDRSSPPLT
KPPEGPKFPRVKNWEVGSITYDTLSAQAQQEGPCTPRRCLGSLVFPRKLQSRPSQDPPPT
EQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEIAAAGTYQLRESELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCNSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFALPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFHYQPDPW
KGSGSKGAGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHRSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAAA
RDIFSAKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPGEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEESGEQQELESLSQDPRRY
EEWKWFRCPTLLEALEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKAGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIDSKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSRE
PDCPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGPDT
PSP
NT seq
3612 nt
NT seq
+upstream
nt +downstream
nt
atgggcaatttgaagagtgtgggccaggagccggggcctccctgcggcctggggctgggg
ctgggcctgggcctgtgcggcaagcagggcccagcctccccgacagcagagcccggcagg
gcaccggcacccgcacccccacccccacccgcgccagaccgcagcagtcccccgctcacc
aagcccccggaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcact
tacgacaccctgagtgcccaggcacagcaggaggggccctgcacccctagacgctgcctg
ggctccctggtttttccacggaaactgcagagccggccctcccaggacccaccacccact
gagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatcaagagg
agtggctcccaggcccatgagcagaggcttcaggaggtggaagccgagatagcagccgca
ggcacataccagcttcgggagagcgagctggtgttcggggctaagcaggcttggagaaat
gcaccccgctgcgtgggccggatccagtgggggaagctgcaggtgtttgatgcccgggat
tgcaactctgcccaggagatgttcacctacatctgcaaccacatcaagtacgccaccaac
cggggcaacctccgctcggccatcacagtgttcccccagcgcgccccaggccgcggagac
ttccgaatctggaacagccaactggtgcgctacgcggggtacaggcagcaggatggctcc
gtgcggggggacccagccaacgtggagatcactgagctctgcatccagcacggctggacc
ccaggaaacggccgctttgacgtactgcccctactgctccaggccccagatgagccccca
gaactctttgccttgccccccgagctggtcctcgaggtgcccctggagcaccccacgctg
gagtggtttgcggccctgggcctgcgctggtacgccctcccggcggtgagcaacatgctg
ctggaaattggggggctggagttccccgcggcccctttcagcggctggtacatgagcact
gagatcggcacgcggaacctgtgtgacccgcaccgatacaacatcctggaggatgtggcc
gtctgcatggacttggatacccggaccacctcgtccctgtggaaagacaaggcagccgtg
gaaatcaacttggctgtgctgcacagttaccagctggccaaagtgaccattgtggaccac
catgctgccacggcctccttcatgaagcacctggagaatgagcagaaggctagggggggc
tgccctgccgactgggcctggatcgtgccccccatctccggcagcctcacccctgtgttc
catcaggagatggtcaactatgtcctgtcccctgccttccactatcagccagacccgtgg
aagggaagtgggtccaagggtgccggcatcaccaggaagaagacctttaaggaagtggcc
aatgcggtgaagatctctgcctcactcatgggcaccgtgatggcaaagcgagtaaaggca
acaatcctgtatggctccgagaccggccgggcccagagctatgcacagcagctggggaga
ctcttccggaaggctttcgatccccgggtcctgtgcatggatgagtatgatgtcgtgtcc
ctcgagcatgagacgctagtgctggtcgtgaccagcacattcgggaacggtgatcccccc
gagaatggagagagttttgcagcggccctgatggaaatgtctggtccctacaacagctcc
cctcggccagaacaacacaggagttacaaaatccgcttcaacagtgtctcctgctcagac
ccgctggtgtcctcctggaggcggaagagaaaggagtccagtaacacagacagtgcaggg
gcactgggtaccctcaggttctgtgtgttcgggctgggctcccgggcgtacccccacttc
tgtgcctttgcccgtgcggtggacacacggctggaggagctgggtggcgagcggctgctg
cagctgggccagggagatgagctgtgtggccaggaggaggccttccgtggctgggcccag
gccgccttccaggcctcctgtgagactttctgcgtgggagaggacgccaaggctgccgcc
agggacatattcagcgccaaacggagctggaagcgccaaaggtaccggctcagcacccag
gcggagggcctccagctgctgccaggcctgatccacgtgcacaggaggaagatgttccag
gctaccatcctctcagtcgaaaacctgcaaagcagcaagtccacccgggccacgatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggaccacataggc
atctgcccgcccaaccgaccgggcctcgtggaggcgctgctgagccgtgtggaggacccg
cctccgccaggagagcccgtggccgtggagcagctggagaagggcagccctggtggccca
ccccccagctgggttcgggacccccggctgcccccctgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcaactccttcgactgctcagcaccctg
gcggaagagtccggagaacagcaggagctggagagcctcagccaggacccccggcgctac
gaggagtggaagtggttccggtgccccacgctgctggaggcgctggaacagttcccgtcc
gtggcgctgcctgcccccctgctcctcacccagctgcccctgctccagccccggtactac
tccgtcagctcggcgcccagcgcccacccgggagagattcacctcacggtggccgtgctg
gcgtacaggacccaggatggactgggccccctgcactatggagtctgctccacatggctg
agccagctgaaggccggagatcccgtaccttgcttcatcaggggggctccctccttccgg
ctgccgcctgatcccagcttgccctgcatcctagtgggccctggcacaggaattgccccc
ttccggggattttggcaggagcggctgcacgacattgacagcaaagggctgcagccggcc
cccatgaccttggtgttcggctgccgatgctcccagctcgaccacctctaccgcgacgag
gtgcaggatgcccagcagcgcggggtttttggacgcgtcctcacagccttctctcgggag
cccgactgccctaagacctacgtgcaggacatcctgcggacggagctggcggctgaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtgtgcggcgacgtcaccatggca
accagcgtcctgcagacggtgcagcgaatcctagcgacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacattttc
gggctcacgctgcgcacccaggaggtcactagccgcatacgcacccagagcttttccctg
caggagcggcatctgcgcggcgcagtgccctgggcgttcgaccctcccggcccagacacc
cccagtccctga
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