Felis catus (domestic cat): 101096568
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Entry
101096568 CDS
T02385
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca00270
Cysteine and methionine metabolism
fca00480
Glutathione metabolism
fca01100
Metabolic pathways
fca01240
Biosynthesis of cofactors
fca04216
Ferroptosis
Module
fca_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101096568 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101096568 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101096568 (GCLC)
Enzymes [BR:
fca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101096568 (GCLC)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
101096568
NCBI-ProteinID:
XP_023109831
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Position
B2:complement(50879406..50929367)
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AA seq
637 aa
AA seq
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MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPLEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFMETFPEDEEAARASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNSYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTVVDGYGKVQNTSELTTEDYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFISNHPDYKRDSVITDEMNYS
LILKCNQIADELCECPELLGPAFRKVKYSGSKTDPSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagagagtccagttggtcctgtctggagaagaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagaccagagtatggcagttac
atgattgaaggcacacctggacaaccgtacggaggaactatgtccgagttcaacacagtt
gaagacaacatgagaaaacgccggaaggaggcgacctctttattaggagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacgctgccagagttt
aaacccaatccactcgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcatccccgcttcagtaccctaacaagaaatatccgacacaggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatggaaaca
tttcctgaggatgaggaggcagcaagggcttccaagcctgatcatatttacatggatgcc
atgggatttgggatgggtaattgctgtcttcaggtaacgttccaagcctgcagcatatct
gaggccagatacctttatgatcagctggccaccatctgtccaattgtcatggctttgagt
gctgcgtctcctttttaccgaggctatgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaat
agctataggatcagtaaatcccgatatgattcaatagacagttatttatctgagtgtggg
gagaaatacaatgacatcgacttgacaattgataaagaaatctacgaacagctgctgcag
gaaggcattgatcatctcctggcccagcacgtcgctcatctcttcatcagagacccactg
actctgtttgaagagaaaatacacttggatgatgccaatgaatcggaccattttgagaac
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactctgacatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttacaagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgatgaaaacatgaaagttgcacagaaacgagatgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtgggaacactgtggtggatggc
tacgggaaggtccagaacacctcggaactgaccacggaggactacaccctgatgagcata
gacaccatcatcaacgggaaggagggtgtgtttcctgggctgatcccgattctgaactct
taccttgaaaacatggaggtggatgtggacactagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgcccgatggatgagagagttt
atctcaaaccatcctgactataagcgagacagtgtaatcactgatgaaatgaactatagc
ctcatcttaaagtgtaaccaaattgcagacgaattgtgtgagtgcccagagttacttgga
ccagcgtttaggaaagtaaaatacagtggaagtaaaacggacccttccaactga
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