KEGG   Felis catus (domestic cat): 101101463
Entry
101101463         CDS       T02385                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X3
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
fca  Felis catus (domestic cat)
Pathway
fca01522  Endocrine resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04014  Ras signaling pathway
fca04024  cAMP signaling pathway
fca04068  FoxO signaling pathway
fca04071  Sphingolipid signaling pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04141  Protein processing in endoplasmic reticulum
fca04210  Apoptosis
fca04215  Apoptosis - multiple species
fca04217  Necroptosis
fca04310  Wnt signaling pathway
fca04380  Osteoclast differentiation
fca04510  Focal adhesion
fca04530  Tight junction
fca04620  Toll-like receptor signaling pathway
fca04621  NOD-like receptor signaling pathway
fca04622  RIG-I-like receptor signaling pathway
fca04625  C-type lectin receptor signaling pathway
fca04657  IL-17 signaling pathway
fca04658  Th1 and Th2 cell differentiation
fca04659  Th17 cell differentiation
fca04660  T cell receptor signaling pathway
fca04664  Fc epsilon RI signaling pathway
fca04668  TNF signaling pathway
fca04722  Neurotrophin signaling pathway
fca04723  Retrograde endocannabinoid signaling
fca04728  Dopaminergic synapse
fca04750  Inflammatory mediator regulation of TRP channels
fca04910  Insulin signaling pathway
fca04912  GnRH signaling pathway
fca04914  Progesterone-mediated oocyte maturation
fca04917  Prolactin signaling pathway
fca04920  Adipocytokine signaling pathway
fca04926  Relaxin signaling pathway
fca04930  Type II diabetes mellitus
fca04931  Insulin resistance
fca04932  Non-alcoholic fatty liver disease
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca04935  Growth hormone synthesis, secretion and action
fca04936  Alcoholic liver disease
fca05010  Alzheimer disease
fca05012  Parkinson disease
fca05016  Huntington disease
fca05017  Spinocerebellar ataxia
fca05020  Prion disease
fca05022  Pathways of neurodegeneration - multiple diseases
fca05132  Salmonella infection
fca05133  Pertussis
fca05135  Yersinia infection
fca05142  Chagas disease
fca05145  Toxoplasmosis
fca05152  Tuberculosis
fca05161  Hepatitis B
fca05162  Measles
fca05166  Human T-cell leukemia virus 1 infection
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05169  Epstein-Barr virus infection
fca05170  Human immunodeficiency virus 1 infection
fca05171  Coronavirus disease - COVID-19
fca05200  Pathways in cancer
fca05208  Chemical carcinogenesis - reactive oxygen species
fca05210  Colorectal cancer
fca05212  Pancreatic cancer
fca05231  Choline metabolism in cancer
fca05415  Diabetic cardiomyopathy
fca05417  Lipid and atherosclerosis
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101101463 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101101463 (MAPK10)
   04012 ErbB signaling pathway
    101101463 (MAPK10)
   04014 Ras signaling pathway
    101101463 (MAPK10)
   04310 Wnt signaling pathway
    101101463 (MAPK10)
   04668 TNF signaling pathway
    101101463 (MAPK10)
   04068 FoxO signaling pathway
    101101463 (MAPK10)
   04071 Sphingolipid signaling pathway
    101101463 (MAPK10)
   04024 cAMP signaling pathway
    101101463 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101101463 (MAPK10)
   04137 Mitophagy - animal
    101101463 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    101101463 (MAPK10)
   04215 Apoptosis - multiple species
    101101463 (MAPK10)
   04217 Necroptosis
    101101463 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101101463 (MAPK10)
   04530 Tight junction
    101101463 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101101463 (MAPK10)
   04621 NOD-like receptor signaling pathway
    101101463 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    101101463 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    101101463 (MAPK10)
   04660 T cell receptor signaling pathway
    101101463 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    101101463 (MAPK10)
   04659 Th17 cell differentiation
    101101463 (MAPK10)
   04657 IL-17 signaling pathway
    101101463 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    101101463 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101101463 (MAPK10)
   04920 Adipocytokine signaling pathway
    101101463 (MAPK10)
   04912 GnRH signaling pathway
    101101463 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    101101463 (MAPK10)
   04917 Prolactin signaling pathway
    101101463 (MAPK10)
   04926 Relaxin signaling pathway
    101101463 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    101101463 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    101101463 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    101101463 (MAPK10)
   04722 Neurotrophin signaling pathway
    101101463 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101101463 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101101463 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101101463 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    101101463 (MAPK10)
   05231 Choline metabolism in cancer
    101101463 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101101463 (MAPK10)
   05212 Pancreatic cancer
    101101463 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101101463 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    101101463 (MAPK10)
   05161 Hepatitis B
    101101463 (MAPK10)
   05171 Coronavirus disease - COVID-19
    101101463 (MAPK10)
   05162 Measles
    101101463 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101101463 (MAPK10)
   05169 Epstein-Barr virus infection
    101101463 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101101463 (MAPK10)
   05135 Yersinia infection
    101101463 (MAPK10)
   05133 Pertussis
    101101463 (MAPK10)
   05152 Tuberculosis
    101101463 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101101463 (MAPK10)
   05142 Chagas disease
    101101463 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101101463 (MAPK10)
   05012 Parkinson disease
    101101463 (MAPK10)
   05016 Huntington disease
    101101463 (MAPK10)
   05017 Spinocerebellar ataxia
    101101463 (MAPK10)
   05020 Prion disease
    101101463 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    101101463 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101101463 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    101101463 (MAPK10)
   05415 Diabetic cardiomyopathy
    101101463 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101101463 (MAPK10)
   04936 Alcoholic liver disease
    101101463 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    101101463 (MAPK10)
   04931 Insulin resistance
    101101463 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101101463 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101101463 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    101101463 (MAPK10)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101101463 (MAPK10)
Protein kinases [BR:fca01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101101463 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 101101463
NCBI-ProteinID: XP_019684831
LinkDB
Position
B1:133907681..134464378
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggtttcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccaattctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttaaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgccgttcttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacgcatgccaagagagcttaccgggagctagtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacactggaggagttccag
gatgtttacttagtaatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctc
cactctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactcgccagaacggcaggcacaagtttcatgatg
actccttatgtggttacccgttattatagagcccctgaggttattctgggaatgggctac
aaggagaacgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtgattgagcaactagga
acgccatgcccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactccgagcacaataaactcaaagccagccaagccagggacttattgtcaaagatgcta
gtgattgatccagcaaaaaggatatccgtggatgacgccttacaacacccttacatcaat
gtctggtacgaccctgccgaagtggaggcgcctccacctcagatatatgacaaacagttg
gacgaaagagaacacaccattgaagaatggaaagaacttatctacaaggaggtaatgaat
tcggaagaaaagactaaaaatggtgttgtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtctgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcctcagcaggacccctg
ggttgttgcaggtga

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