KEGG   Felis catus (domestic cat): 105260786
Entry
105260786         CDS       T02385                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
fca  Felis catus (domestic cat)
Pathway
fca01522  Endocrine resistance
fca04010  MAPK signaling pathway
fca04015  Rap1 signaling pathway
fca04068  FoxO signaling pathway
fca04071  Sphingolipid signaling pathway
fca04114  Oocyte meiosis
fca04148  Efferocytosis
fca04218  Cellular senescence
fca04261  Adrenergic signaling in cardiomyocytes
fca04370  VEGF signaling pathway
fca04380  Osteoclast differentiation
fca04550  Signaling pathways regulating pluripotency of stem cells
fca04611  Platelet activation
fca04613  Neutrophil extracellular trap formation
fca04620  Toll-like receptor signaling pathway
fca04621  NOD-like receptor signaling pathway
fca04622  RIG-I-like receptor signaling pathway
fca04625  C-type lectin receptor signaling pathway
fca04657  IL-17 signaling pathway
fca04658  Th1 and Th2 cell differentiation
fca04659  Th17 cell differentiation
fca04660  T cell receptor signaling pathway
fca04664  Fc epsilon RI signaling pathway
fca04668  TNF signaling pathway
fca04670  Leukocyte transendothelial migration
fca04714  Thermogenesis
fca04722  Neurotrophin signaling pathway
fca04723  Retrograde endocannabinoid signaling
fca04728  Dopaminergic synapse
fca04750  Inflammatory mediator regulation of TRP channels
fca04912  GnRH signaling pathway
fca04914  Progesterone-mediated oocyte maturation
fca04917  Prolactin signaling pathway
fca04926  Relaxin signaling pathway
fca04932  Non-alcoholic fatty liver disease
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca04935  Growth hormone synthesis, secretion and action
fca04936  Alcoholic liver disease
fca05014  Amyotrophic lateral sclerosis
fca05020  Prion disease
fca05022  Pathways of neurodegeneration - multiple diseases
fca05132  Salmonella infection
fca05133  Pertussis
fca05135  Yersinia infection
fca05140  Leishmaniasis
fca05142  Chagas disease
fca05145  Toxoplasmosis
fca05152  Tuberculosis
fca05161  Hepatitis B
fca05163  Human cytomegalovirus infection
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05169  Epstein-Barr virus infection
fca05170  Human immunodeficiency virus 1 infection
fca05171  Coronavirus disease - COVID-19
fca05205  Proteoglycans in cancer
fca05208  Chemical carcinogenesis - reactive oxygen species
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05415  Diabetic cardiomyopathy
fca05417  Lipid and atherosclerosis
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    105260786 (MAPK11)
   04015 Rap1 signaling pathway
    105260786 (MAPK11)
   04370 VEGF signaling pathway
    105260786 (MAPK11)
   04668 TNF signaling pathway
    105260786 (MAPK11)
   04068 FoxO signaling pathway
    105260786 (MAPK11)
   04071 Sphingolipid signaling pathway
    105260786 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    105260786 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    105260786 (MAPK11)
   04218 Cellular senescence
    105260786 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    105260786 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105260786 (MAPK11)
   04613 Neutrophil extracellular trap formation
    105260786 (MAPK11)
   04620 Toll-like receptor signaling pathway
    105260786 (MAPK11)
   04621 NOD-like receptor signaling pathway
    105260786 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    105260786 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    105260786 (MAPK11)
   04660 T cell receptor signaling pathway
    105260786 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    105260786 (MAPK11)
   04659 Th17 cell differentiation
    105260786 (MAPK11)
   04657 IL-17 signaling pathway
    105260786 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    105260786 (MAPK11)
   04670 Leukocyte transendothelial migration
    105260786 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    105260786 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    105260786 (MAPK11)
   04917 Prolactin signaling pathway
    105260786 (MAPK11)
   04926 Relaxin signaling pathway
    105260786 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    105260786 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105260786 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    105260786 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    105260786 (MAPK11)
   04722 Neurotrophin signaling pathway
    105260786 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    105260786 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    105260786 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    105260786 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    105260786 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    105260786 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    105260786 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    105260786 (MAPK11)
   05161 Hepatitis B
    105260786 (MAPK11)
   05171 Coronavirus disease - COVID-19
    105260786 (MAPK11)
   05163 Human cytomegalovirus infection
    105260786 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105260786 (MAPK11)
   05169 Epstein-Barr virus infection
    105260786 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    105260786 (MAPK11)
   05135 Yersinia infection
    105260786 (MAPK11)
   05133 Pertussis
    105260786 (MAPK11)
   05152 Tuberculosis
    105260786 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    105260786 (MAPK11)
   05140 Leishmaniasis
    105260786 (MAPK11)
   05142 Chagas disease
    105260786 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    105260786 (MAPK11)
   05020 Prion disease
    105260786 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    105260786 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105260786 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    105260786 (MAPK11)
   05415 Diabetic cardiomyopathy
    105260786 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    105260786 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    105260786 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    105260786 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105260786 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    105260786 (MAPK11)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     105260786 (MAPK11)
Protein kinases [BR:fca01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   105260786 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975
Other DBs
NCBI-GeneID: 105260786
NCBI-ProteinID: XP_023113428
UniProt: M3WG00
LinkDB
Position
B4:complement(141649444..141656066)
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDTRLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFRGANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFKPPEPPQSPGSL
DIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgcgcaggcttctaccggcaggaactcaacaagacggtgtgggaggtg
cctcagcggctgcaggggctgcgcccggtgggctcgggcgcctacggctcggtctgctcg
gcctacgacacgcggctgcgccagaaggtggcagtgaagaagctgtcgcgacccttccag
tcgctgatccacgcgcggaggacctaccgcgagctgcggctgctcaaacacctgaagcac
gagaacgtcatcgggctgctggacgtgttcacgccggccacctccattgaggacttcagc
gaagtgtacctggtgaccaccctgatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtccagttcctggtttaccagctgctgcgcgggctcaagtac
atccactccgcggggatcatccaccgggacctgaagcccagcaacgtggctgtgaacgag
gactgtgagcttaggatcctggactttgggctagcccgccaggctgatgaggagatgacc
ggctatgtggccacccgctggtaccgcgcgcctgagatcatgctcaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggctgagctgctccagggaaag
gccctcttcccaggaaatgactacatcgaccagctgaagcgaatcatggaggtggtgggc
acgcccagccctgaggttctagcaaaaatatcatcggaacacgcccggacatacatccag
tccctgccccccatgccccagaaggacctcaggagcatcttccgtggagccaaccccctg
gctgtggatctcctgggaaggatgctggtgctggacagtgaccagagggtcagtgcggct
gaggccctggcccatgcctacttcagccagtaccacgaccccgacgatgagcccgaggct
gagccctatgatgaaagcgttgaggccaaggagcggaccgtggaggagtggaaggagctc
acctaccaggaggtcctcagcttcaagcccccagagccaccgcagtcacctggcagcctg
gatattgagcagtga

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